| Reaction Details |
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 | Report a problem with these data |
| Target | Lethal(3)malignant brain tumor-like protein 3 |
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| Ligand | BDBM50496581 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1300220 (CHEMBL3136684) |
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| IC50 | 37±n/a nM |
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| Citation |  Camerino, MA; Zhong, N; Dong, A; Dickson, BM; James, LI; Baughman, BM; Norris, JL; Kireev, DB; Janzen, WP; Arrowsmith, CH; Frye, SV The structure-activity relationships of L3MBTL3 inhibitors: flexibility of the dimer interface. Medchemcomm4:1501-1507 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Lethal(3)malignant brain tumor-like protein 3 |
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| Name: | Lethal(3)malignant brain tumor-like protein 3 |
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| Synonyms: | H-l(3)mbt-like protein 3 | KIAA1798 | L(3)mbt-like protein 3 | L3MBTL3 | LMBL3_HUMAN | Lethal(3)malignant brain tumor-like protein 3 | Lethal(3)malignant brain tumor-like protein 3 (L3MBTL3) | MBT-1 | MBT1 |
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| Type: | Protein |
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| Mol. Mass.: | 88334.17 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 780 |
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| Sequence: | MTESASSTSGQEFDVFSVMDWKDGVGTLPGSDLKFRVNEFGALEVITDENEMENVKKATA
TTTWMVPTAQEAPTSPPSSRPVFPPAYWTSPPGCPTVFSEKTGMPFRLKDPVKVEGLQFC
ENCCQYGNVDECLSGGNYCSQNCARHIKDKDQKEERDVEEDNEEEDPKCSRKKKPKLSLK
ADTKEDGEERDDEMENKQDVRILRGSQRARRKRRGDSAVLKQGLPPKGKKAWCWASYLEE
EKAVAVPAKLFKEHQSFPYNKNGFKVGMKLEGVDPEHQSVYCVLTVAEVCGYRIKLHFDG
YSDCYDFWVNADALDIHPVGWCEKTGHKLHPPKGYKEEEFNWQTYLKTCKAQAAPKSLFE
NQNITVIPSGFRVGMKLEAVDKKNPSFICVATVTDMVDNRFLVHFDNWDESYDYWCEASS
PHIHPVGWCKEHRRTLITPPGYPNVKHFSWDKYLEETNSLPAPARAFKVKPPHGFQKKMK
LEVVDKRNPMFIRVATVADTDDHRVKVHFDGWNNCYDYWIDADSPDIHPVGWCSKTGHPL
QPPLSPLELMEASEHGGCSTPGCKGIGHFKRARHLGPHSAANCPYSEINLNKDRIFPDRL
SGEMPPASPSFPRNKRTDANESSSSPEIRDQHADDVKEDFEERTESEMRTSHEARGAREE
PTVQQAQRRSAVFLSFKSPIPCLPLRWEQQSKLLPTVAGIPASKVSKWSTDEVSEFIQSL
PGCEEHGKVFKDEQIDGEAFLLMTQTDIVKIMSIKLGPALKIFNSILMFKAAEKNSHNEL
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| BDBM50496581 |
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| n/a |
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| Name | BDBM50496581 |
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| Synonyms: | CHEMBL3134130 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H32ClN3 |
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| Mol. Mass. | 361.952 |
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| SMILES | Clc1cc(ccc1CCN1CCCC1)N1CCC(CC1)N1CCCC1 |
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| Structure | 
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