| Reaction Details |
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 | Report a problem with these data |
| Target | Lethal(3)malignant brain tumor-like protein 3 |
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| Ligand | BDBM50440614 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1300220 (CHEMBL3136684) |
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| IC50 | 24±n/a nM |
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| Citation |  Camerino, MA; Zhong, N; Dong, A; Dickson, BM; James, LI; Baughman, BM; Norris, JL; Kireev, DB; Janzen, WP; Arrowsmith, CH; Frye, SV The structure-activity relationships of L3MBTL3 inhibitors: flexibility of the dimer interface. Medchemcomm4:1501-1507 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Lethal(3)malignant brain tumor-like protein 3 |
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| Name: | Lethal(3)malignant brain tumor-like protein 3 |
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| Synonyms: | H-l(3)mbt-like protein 3 | KIAA1798 | L(3)mbt-like protein 3 | L3MBTL3 | LMBL3_HUMAN | Lethal(3)malignant brain tumor-like protein 3 | Lethal(3)malignant brain tumor-like protein 3 (L3MBTL3) | MBT-1 | MBT1 |
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| Type: | Protein |
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| Mol. Mass.: | 88334.17 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 780 |
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| Sequence: | MTESASSTSGQEFDVFSVMDWKDGVGTLPGSDLKFRVNEFGALEVITDENEMENVKKATA
TTTWMVPTAQEAPTSPPSSRPVFPPAYWTSPPGCPTVFSEKTGMPFRLKDPVKVEGLQFC
ENCCQYGNVDECLSGGNYCSQNCARHIKDKDQKEERDVEEDNEEEDPKCSRKKKPKLSLK
ADTKEDGEERDDEMENKQDVRILRGSQRARRKRRGDSAVLKQGLPPKGKKAWCWASYLEE
EKAVAVPAKLFKEHQSFPYNKNGFKVGMKLEGVDPEHQSVYCVLTVAEVCGYRIKLHFDG
YSDCYDFWVNADALDIHPVGWCEKTGHKLHPPKGYKEEEFNWQTYLKTCKAQAAPKSLFE
NQNITVIPSGFRVGMKLEAVDKKNPSFICVATVTDMVDNRFLVHFDNWDESYDYWCEASS
PHIHPVGWCKEHRRTLITPPGYPNVKHFSWDKYLEETNSLPAPARAFKVKPPHGFQKKMK
LEVVDKRNPMFIRVATVADTDDHRVKVHFDGWNNCYDYWIDADSPDIHPVGWCSKTGHPL
QPPLSPLELMEASEHGGCSTPGCKGIGHFKRARHLGPHSAANCPYSEINLNKDRIFPDRL
SGEMPPASPSFPRNKRTDANESSSSPEIRDQHADDVKEDFEERTESEMRTSHEARGAREE
PTVQQAQRRSAVFLSFKSPIPCLPLRWEQQSKLLPTVAGIPASKVSKWSTDEVSEFIQSL
PGCEEHGKVFKDEQIDGEAFLLMTQTDIVKIMSIKLGPALKIFNSILMFKAAEKNSHNEL
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| BDBM50440614 |
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| n/a |
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| Name | BDBM50440614 |
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| Synonyms: | CHEMBL2426364 |
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| Type | Small organic molecule |
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| Emp. Form. | C32H43N5O2 |
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| Mol. Mass. | 529.7161 |
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| SMILES | O=C(N1CCC(CC1)N1CCCC1)c1ccc(C(=O)N2CCC(CC2)N2CCCC2)c(Nc2ccccc2)c1 |
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| Structure | 
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