| Reaction Details |
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 | Report a problem with these data |
| Target | Lutropin-choriogonadotropic hormone receptor |
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| Ligand | BDBM50189778 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1328819 (CHEMBL3227403) |
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| EC50 | 220±n/a nM |
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| Citation |  Englund, EE; Neumann, S; Eliseeva, E; McCoy, JG; Titus, S; Zheng, W; Southall, N; Shin, P; Leister, W; Thomas, CJ; Inglese, J; Austin, CP; Gershengorn, MC; Huang, W The Synthesis and Evaluation of Dihydroquinazolin-4-ones and Quinazolin-4-ones as Thyroid Stimulating Hormone Receptor Agonists. Medchemcomm2:1016-1020 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Lutropin-choriogonadotropic hormone receptor |
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| Name: | Lutropin-choriogonadotropic hormone receptor |
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| Synonyms: | LCGR | LGR2 | LH/CG-R | LHCGR | LHR | LHRHR | LSH-R | LSHR_HUMAN | Luteinizing hormone receptor |
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| Type: | PROTEIN |
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| Mol. Mass.: | 78662.77 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_562598 |
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| Residue: | 699 |
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| Sequence: | MKQRFSALQLLKLLLLLQPPLPRALREALCPEPCNCVPDGALRCPGPTAGLTRLSLAYLP
VKVIPSQAFRGLNEVIKIEISQIDSLERIEANAFDNLLNLSEILIQNTKNLRYIEPGAFI
NLPRLKYLSICNTGIRKFPDVTKVFSSESNFILEICDNLHITTIPGNAFQGMNNESVTLK
LYGNGFEEVQSHAFNGTTLTSLELKENVHLEKMHNGAFRGATGPKTLDISSTKLQALPSY
GLESIQRLIATSSYSLKKLPSRETFVNLLEATLTYPSHCCAFRNLPTKEQNFSHSISENF
SKQCESTVRKVNNKTLYSSMLAESELSGWDYEYGFCLPKTPRCAPEPDAFNPCEDIMGYD
FLRVLIWLINILAIMGNMTVLFVLLTSRYKLTVPRFLMCNLSFADFCMGLYLLLIASVDS
QTKGQYYNHAIDWQTGSGCSTAGFFTVFASELSVYTLTVITLERWHTITYAIHLDQKLRL
RHAILIMLGGWLFSSLIAMLPLVGVSNYMKVSICFPMDVETTLSQVYILTILILNVVAFF
IICACYIKIYFAVRNPELMATNKDTKIAKKMAILIFTDFTCMAPISFFAISAAFKVPLIT
VTNSKVLLVLFYPINSCANPFLYAIFTKTFQRDFFLLLSKFGCCKRRAELYRRKDFSAYT
SNCKNGFTGSNKPSQSTLKLSTLHCQGTALLDKTRYTEC
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| BDBM50189778 |
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| n/a |
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| Name | BDBM50189778 |
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| Synonyms: | CHEMBL211405 | N-tert-butyl-5-amino-4-(3-methoxyphenyl)-2-(methylthio)thieno[2,3-d]pyrimidine-6-carboxamide | ORG-41841 | cid_9887381 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H22N4O2S2 |
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| Mol. Mass. | 402.534 |
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| SMILES | COc1cccc(c1)-c1nc(SC)nc2sc(C(=O)NC(C)(C)C)c(N)c12 |
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| Structure | 
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