| Reaction Details |
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 | Report a problem with these data |
| Target | GTPase KRas |
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| Ligand | BDBM50496837 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1331356 (CHEMBL3223234) |
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| Kd | 830±n/a nM |
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| Citation |  Wu, X; Upadhyaya, P; Villalona-Calero, MA; Briesewitz, R; Pei, D Inhibition of Ras-Effector Interaction by Cyclic Peptides. Medchemcomm4:378-382 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| GTPase KRas |
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| Name: | GTPase KRas |
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| Synonyms: | GTPase KRas, N-terminally processed | K-Ras 2 | KRAS | KRAS2 | Ki-Ras | RASK2 | RASK_HUMAN | c-K-ras | c-Ki-ras |
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| Type: | PROTEIN |
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| Mol. Mass.: | 21656.10 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1476955 |
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| Residue: | 189 |
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| Sequence: | MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG
QEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDL
PSRTVDTKQAQDLARSYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLKKISKEEKTPGC
VKIKKCIIM
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| BDBM50496837 |
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| n/a |
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| Name | BDBM50496837 |
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| Synonyms: | CHEMBL3218641 |
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| Type | Small organic molecule |
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| Emp. Form. | C74H104FN19O13 |
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| Mol. Mass. | 1486.7355 |
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| SMILES | [H][C@@]12[#6]-[#6]-[#6]-[#6]-[#7]1-[#6](=O)-[#6](=O)C([#6])([#6])[#6]-[#8]-[#6](=O)-[#6@@H](-[#6]-[#6]-[#6]-[#6])-[#7]-[#6](=O)-[#6@H](-[#6]-c1ccc(F)cc1)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#7]-[#6](=O)-[#6@@H](-[#6]-c1ccc3ccccc3c1)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6](-[#7])=O)-[#7]-[#6](=O)-[#6]-[#6@@H](-[#6]-[#6]-c1ccccc1)-[#7]-[#6]2=O |r| |
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| Structure | 
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