| Reaction Details |
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 | Report a problem with these data |
| Target | Neuraminidase |
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| Ligand | BDBM50028503 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1337293 (CHEMBL3241017) |
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| IC50 | 1.3±n/a nM |
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| Citation |  Mooney, CA; Johnson, SA; 't Hart, P; Quarles van Ufford, L; de Haan, CA; Moret, EE; Martin, NI Oseltamivir analogues bearing N-substituted guanidines as potent neuraminidase inhibitors. J Med Chem57:3154-60 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Neuraminidase |
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| Name: | Neuraminidase |
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| Synonyms: | NA | NRAM_I33A0 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 49687.56 |
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| Organism: | Influenza A virus |
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| Description: | ChEMBL_1347422 |
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| Residue: | 453 |
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| Sequence: | MNPNQKIITIGSICMVVGIISLILQIGNIISIWISHSIQTGNQNHTGICNQGIITYNVVA
GQDSTSVILTGNSSLCPIRGWAIHSKDNGIRIGSKGDVFVIREPFISCSHLECRTFFLTQ
GALLNDKHSNGTVKDRSPYRALMSCPVGEAPSPYNSRFESVAWSASACHDGMGWLTIGIS
GPDNGAVAVLKYNGIITETIKSWRKKILRTQESECTCVNGSCFTIMTDGPSNGLASYKIF
KIEKGKVTKSIELNAPNSHYEECSCYPDTGKVMCVCRDNWHGSNRPWVSFDQNLDYQIGY
ICSGVFGDNPRPKDGPGSCGPVSADGANGVKGFSYRYGNGVWIGRTKSDSSRHGFEMIWD
PNGWTETDSRFSVRQDVVAMTDRSGYSGSFVQHPELTGLDCMRPCFWVELIRGRPEEETI
WTSGSIISFCGVNSDTVDWSWPDGAELPFTIDK
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| BDBM50028503 |
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| n/a |
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| Name | BDBM50028503 |
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| Synonyms: | CHEMBL81717 | Guanidino-Oseltamivir Carboxylicacid |
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| Type | Small organic molecule |
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| Emp. Form. | C15H26N4O4 |
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| Mol. Mass. | 326.3913 |
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| SMILES | CCC(CC)O[C@@H]1C=C(C[C@H](NC(N)=N)[C@H]1NC(C)=O)C(O)=O |r,c:7| |
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| Structure | 
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