| Reaction Details |
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 | Report a problem with these data |
| Target | Sensory histidine kinase DcuS |
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| Ligand | BDBM50497022 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1335394 (CHEMBL3239045) |
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| Kd | 222000±n/a nM |
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| Citation |  Murray, EJ; Crowley, RC; Truman, A; Clarke, SR; Cottam, JA; Jadhav, GP; Steele, VR; O'Shea, P; Lindholm, C; Cockayne, A; Chhabra, SR; Chan, WC; Williams, P Targeting Staphylococcus aureus quorum sensing with nonpeptidic small molecule inhibitors. J Med Chem57:2813-9 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sensory histidine kinase DcuS |
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| Name: | Sensory histidine kinase DcuS |
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| Synonyms: | Receptor-histidine kinase AgrC |
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| Type: | PROTEIN |
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| Mol. Mass.: | 49890.25 |
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| Organism: | Staphylococcus aureus |
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| Description: | ChEMBL_305973 |
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| Residue: | 430 |
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| Sequence: | MELLNSYNFVLFVLTQMILMFTIPAIISGIKYSKLDYFFIIVISTLSLFLFKMFDSASLI
ILTSFIIIMYFVKIKWYSILLIMTSQIILYCANYMYIVIYAYITKISDSIFVIFPSFFVV
YVTISILFSYIINRVLKKISTPYLILNKGFLIVISTILLLTFSLFFFYSQINSDEAKVIR
QYSFIFIGITIFLSILTFVISQFLLKEMKYKRNQEEIETYYEYTLKIEAINNEMRKFRHD
YVNILTTLSEYIREDDMPGLRDYFNKNIVPMKDNLQMNAIKLNGIENLKVREIKGLITAK
ILRAQEMNIPISIEIPDEVSSINLNMIDLSRSIGIILDNAIEASTEIDDPIIRVAFIESE
NSVTFIVMNKCADDIPRIHELFQESFSTKGEGRGLGLSTLKEIADNADNVLLDTIIENGF
FIQKVEIINN
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| BDBM50497022 |
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| n/a |
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| Name | BDBM50497022 |
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| Synonyms: | CHEMBL1213657 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H27NO4 |
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| Mol. Mass. | 297.3899 |
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| SMILES | CCCCCCCCC\C(O)=C1\C(=O)N[C@@H](CCO)C1=O |r| |
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| Structure | 
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