| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Retinoic acid receptor alpha |
|---|
| Ligand | BDBM50045269 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_163483 |
|---|
| EC50 | 5000±n/a nM |
|---|
| Citation |  Jong, L; Lehmann, JM; Hobbs, PD; Harlev, E; Huffman, JC; Pfahl, M; Dawson, MI Conformational effects on retinoid receptor selectivity. 1. Effect of 9-double bond geometry on retinoid X receptor activity. J Med Chem36:2605-13 (1993) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Retinoic acid receptor alpha |
|---|
| Name: | Retinoic acid receptor alpha |
|---|
| Synonyms: | NR1B1 | Nuclear receptor subfamily 1 group B member 1 | RAR-alpha | RARA | RARA_HUMAN | Retinoic acid receptor alpha | Retinoic acid receptor alpha/Retinoid X receptor alpha | Retinoid X receptor gamma/retinoic acid receptor alpha | Retinoid receptor |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 50778.87 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_1466191 |
|---|
| Residue: | 462 |
|---|
| Sequence: | MASNSSSCPTPGGGHLNGYPVPPYAFFFPPMLGGLSPPGALTTLQHQLPVSGYSTPSPAT
IETQSSSSEEIVPSPPSPPPLPRIYKPCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNM
VYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKESVRNDRNKKKKEVPKPECSESYTL
TPEVGELIEKVRKAHQETFPALCQLGKYTTNNSSEQRVSLDIDLWDKFSELSTKCIIKTV
EFAKQLPGFTTLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRTQMHNA
GFGPLTDLVFAFANQLLPLEMDDAETGLLSAICLICGDRQDLEQPDRVDMLQEPLLEALK
VYVRKRRPSRPHMFPKMLMKITDLRSISAKGAERVITLKMEIPGSMPPLIQEMLENSEGL
DTLSGQPGGGGRDGGGLAPPPGSCSPSLSPSSNRSSPATHSP
|
|
|
|---|
| BDBM50045269 |
|---|
| n/a |
|---|
| Name | BDBM50045269 |
|---|
| Synonyms: | 4-[2-Methyl-4-(2,6,6-trimethyl-cyclohex-1-enyl)-buta-1,3-dienyl]-benzoic acid | CHEMBL26129 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C21H26O2 |
|---|
| Mol. Mass. | 310.4299 |
|---|
| SMILES | C\C(\C=C\C1=C(C)CCCC1(C)C)=C\c1ccc(cc1)C(O)=O |c:4| |
|---|
| Structure | 
|
|---|
Search and Browse
