| Reaction Details |
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 | Report a problem with these data |
| Target | Retinoic acid receptor gamma |
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| Ligand | BDBM50045277 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_163495 |
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| EC50 | 70±n/a nM |
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| Citation |  Jong, L; Lehmann, JM; Hobbs, PD; Harlev, E; Huffman, JC; Pfahl, M; Dawson, MI Conformational effects on retinoid receptor selectivity. 1. Effect of 9-double bond geometry on retinoid X receptor activity. J Med Chem36:2605-13 (1993) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Retinoic acid receptor gamma |
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| Name: | Retinoic acid receptor gamma |
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| Synonyms: | NR1B3 | Nuclear receptor subfamily 1 group B member 3 | RAR-gamma | RARG | RARG_HUMAN | Retinoic acid receptor RXR-alpha/gamma | Retinoic acid receptor gamma | Retinoid receptor |
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| Type: | PROTEIN |
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| Mol. Mass.: | 50345.43 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1458016 |
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| Residue: | 454 |
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| Sequence: | MATNKERLFAAGALGPGSGYPGAGFPFAFPGALRGSPPFEMLSPSFRGLGQPDLPKEMAS
LSVETQSTSSEEMVPSSPSPPPPPRVYKPCFVCNDKSSGYHYGVSSCEGCKGFFRRSIQK
NMVYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKEAVRNDRNKKKKEVKEEGSPDSY
ELSPQLEELITKVSKAHQETFPSLCQLGKYTTNSSADHRVQLDLGLWDKFSELATKCIIK
IVEFAKRLPGFTGLSIADQITLLKAACLDILMLRICTRYTPEQDTMTFSDGLTLNRTQMH
NAGFGPLTDLVFAFAGQLLPLEMDDTETGLLSAICLICGDRMDLEEPEKVDKLQEPLLEA
LRLYARRRRPSQPYMFPRMLMKITDLRGISTKGAERAITLKMEIPGPMPPLIREMLENPE
MFEDDSSQPGPHPNASSEDEVPGGQGKGGLKSPA
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| BDBM50045277 |
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| n/a |
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| Name | BDBM50045277 |
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| Synonyms: | 4-[2-(1,2,3,4-Tetrahydro-1,4-methano-naphthalen-6-yl)-propenyl]-benzoic acid | CHEMBL84681 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H20O2 |
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| Mol. Mass. | 304.3823 |
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| SMILES | C\C(=C\c1ccc(cc1)C(O)=O)c1ccc2C3CCC(C3)c2c1 |
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| Structure | 
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