Reaction Details |
| Report a problem with these data |
Target | Retinoic acid receptor gamma |
---|
Ligand | BDBM50045266 |
---|
Substrate/Competitor | n/a |
---|
Meas. Tech. | ChEBML_163495 |
---|
EC50 | 30±n/a nM |
---|
Citation | Jong, L; Lehmann, JM; Hobbs, PD; Harlev, E; Huffman, JC; Pfahl, M; Dawson, MI Conformational effects on retinoid receptor selectivity. 1. Effect of 9-double bond geometry on retinoid X receptor activity. J Med Chem36:2605-13 (1993) [PubMed] |
---|
More Info.: | Get all data from this article, Assay Method |
---|
|
Retinoic acid receptor gamma |
---|
Name: | Retinoic acid receptor gamma |
Synonyms: | NR1B3 | Nuclear receptor subfamily 1 group B member 3 | RAR-gamma | RARG | RARG_HUMAN | Retinoic acid receptor RXR-alpha/gamma | Retinoic acid receptor gamma | Retinoid receptor |
Type: | PROTEIN |
Mol. Mass.: | 50345.43 |
Organism: | Homo sapiens (Human) |
Description: | ChEMBL_1458016 |
Residue: | 454 |
Sequence: | MATNKERLFAAGALGPGSGYPGAGFPFAFPGALRGSPPFEMLSPSFRGLGQPDLPKEMAS
LSVETQSTSSEEMVPSSPSPPPPPRVYKPCFVCNDKSSGYHYGVSSCEGCKGFFRRSIQK
NMVYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKEAVRNDRNKKKKEVKEEGSPDSY
ELSPQLEELITKVSKAHQETFPSLCQLGKYTTNSSADHRVQLDLGLWDKFSELATKCIIK
IVEFAKRLPGFTGLSIADQITLLKAACLDILMLRICTRYTPEQDTMTFSDGLTLNRTQMH
NAGFGPLTDLVFAFAGQLLPLEMDDTETGLLSAICLICGDRMDLEEPEKVDKLQEPLLEA
LRLYARRRRPSQPYMFPRMLMKITDLRGISTKGAERAITLKMEIPGPMPPLIREMLENPE
MFEDDSSQPGPHPNASSEDEVPGGQGKGGLKSPA
|
|
|
BDBM50045266 |
---|
n/a |
---|
Name | BDBM50045266 |
Synonyms: | 4-[(E)-2-(4,4-Dimethyl-thiochroman-6-yl)-propenyl]-benzoic acid | 4-[2-(4,4-Dimethyl-thiochroman-6-yl)-propenyl]-benzoic acid | CHEMBL39344 |
Type | Small organic molecule |
Emp. Form. | C21H22O2S |
Mol. Mass. | 338.463 |
SMILES | C\C(=C/c1ccc(cc1)C(O)=O)c1ccc2SCCC(C)(C)c2c1 |
Structure |
|