| Reaction Details |
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 | Report a problem with these data |
| Target | Gastricsin |
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| Ligand | BDBM50045291 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_71514 |
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| Ki | >4000±n/a nM |
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| Citation |  Rao, CM; Scarborough, PE; Kay, J; Batley, B; Rapundalo, S; Klutchko, S; Taylor, MD; Lunney, EA; Humblet, CC; Dunn, BM Specificity in the binding of inhibitors to the active site of human/primate aspartic proteinases: analysis of P2-P1-P1'-P2' variation. J Med Chem36:2614-20 (1993) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Gastricsin |
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| Name: | Gastricsin |
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| Synonyms: | Gastricsin | PEPC_HUMAN | PGC | Pepsinogen C |
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| Type: | PROTEIN |
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| Mol. Mass.: | 42409.17 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1452207 |
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| Residue: | 388 |
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| Sequence: | MKWMVVVLVCLQLLEAAVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLS
VTYEPMAYMDAAYFGEISIGTPPQNFLVLFDTGSSNLWVPSVYCQSQACTSHSRFNPSES
STYSTNGQTFSLQYGSGSLTGFFGYDTLTVQSIQVPNQEFGLSENEPGTNFVYAQFDGIM
GLAYPALSVDEATTAMQGMVQEGALTSPVFSVYLSNQQGSSGGAVVFGGVDSSLYTGQIY
WAPVTQELYWQIGIEEFLIGGQASGWCSEGCQAIVDTGTSLLTVPQQYMSALLQATGAQE
DEYGQFLVNCNSIQNLPSLTFIINGVEFPLPPSSYILSNNGYCTVGVEPTYLSSQNGQPL
WILGDVFLRSYYSVYDLGNNRVGFATAA
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| BDBM50045291 |
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| n/a |
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| Name | BDBM50045291 |
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| Synonyms: | CHEMBL88340 | i2-[2-(Morpholine-4-sulfonylamino)-3-phenyl-propionylamino]-pent-4-enoic acid [1-cyclohexylmethyl-3,3-difluoro-2-hydroxy-3-(2-morpholin-4-yl-ethylcarbamoyl)-propyl]-amide |
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| Type | Small organic molecule |
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| Emp. Form. | C35H54F2N6O8S |
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| Mol. Mass. | 756.9 |
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| SMILES | O[C@H]([C@H](CC1CCCCC1)NC(=O)[C@H](CC=C)NC(=O)[C@H](Cc1ccccc1)NS(=O)(=O)N1CCOCC1)C(F)(F)C(=O)NCCN1CCOCC1 |
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| Structure | 
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