| Reaction Details |
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 | Report a problem with these data |
| Target | Gastricsin |
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| Ligand | BDBM50045290 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_71514 |
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| Ki | 9±n/a nM |
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| Citation |  Rao, CM; Scarborough, PE; Kay, J; Batley, B; Rapundalo, S; Klutchko, S; Taylor, MD; Lunney, EA; Humblet, CC; Dunn, BM Specificity in the binding of inhibitors to the active site of human/primate aspartic proteinases: analysis of P2-P1-P1'-P2' variation. J Med Chem36:2614-20 (1993) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Gastricsin |
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| Name: | Gastricsin |
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| Synonyms: | Gastricsin | PEPC_HUMAN | PGC | Pepsinogen C |
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| Type: | PROTEIN |
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| Mol. Mass.: | 42409.17 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1452207 |
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| Residue: | 388 |
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| Sequence: | MKWMVVVLVCLQLLEAAVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLS
VTYEPMAYMDAAYFGEISIGTPPQNFLVLFDTGSSNLWVPSVYCQSQACTSHSRFNPSES
STYSTNGQTFSLQYGSGSLTGFFGYDTLTVQSIQVPNQEFGLSENEPGTNFVYAQFDGIM
GLAYPALSVDEATTAMQGMVQEGALTSPVFSVYLSNQQGSSGGAVVFGGVDSSLYTGQIY
WAPVTQELYWQIGIEEFLIGGQASGWCSEGCQAIVDTGTSLLTVPQQYMSALLQATGAQE
DEYGQFLVNCNSIQNLPSLTFIINGVEFPLPPSSYILSNNGYCTVGVEPTYLSSQNGQPL
WILGDVFLRSYYSVYDLGNNRVGFATAA
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| BDBM50045290 |
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| n/a |
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| Name | BDBM50045290 |
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| Synonyms: | 2-[2-(Morpholine-4-sulfonylamino)-3-phenyl-propionylamino]-pent-4-enoic acid [1-cyclohexylmethyl-3,3-difluoro-3-(2-methyl-butylcarbamoyl)-2-oxo-propyl]-amide | CHEMBL88415 |
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| Type | Small organic molecule |
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| Emp. Form. | C34H51F2N5O7S |
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| Mol. Mass. | 711.86 |
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| SMILES | CC[C@H](C)CNC(=O)C(F)(F)C(=O)[C@H](CC1CCCCC1)NC(=O)[C@H](CC=C)NC(=O)[C@H](Cc1ccccc1)NS(=O)(=O)N1CCOCC1 |
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| Structure | 
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