| Reaction Details |
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 | Report a problem with these data |
| Target | Integrase |
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| Ligand | BDBM50498473 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1506589 (CHEMBL3598342) |
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| IC50 | 20000±n/a nM |
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| Citation |  Tintori, C; Esposito, F; Morreale, F; Martini, R; Tramontano, E; Botta, M Investigation on the sucrose binding pocket of HIV-1 Integrase by molecular dynamics and synergy experiments. Bioorg Med Chem Lett25:3013-6 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Integrase |
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| Name: | Integrase |
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| Synonyms: | pol |
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| Type: | PROTEIN |
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| Mol. Mass.: | 32203.43 |
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| Organism: | Human immunodeficiency virus 1 |
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| Description: | ChEMBL_106649 |
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| Residue: | 288 |
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| Sequence: | FLDGIDKAQEEHEKYHSNWRAMASDFNLPPVVAKEIVASCDKCQLKGEAMHGQVDCSPGI
WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKTVHTDNGSN
FTSTTVKAACWWAGIKQEFGIPYNPQSQGVIESMNKELKKIIGQVRDQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIVDIIATDIQTKELQKQITKIQNFRVYYRDSRDPVWKGPAK
LLWKGEGAVVIQDNSDIKVVPRRKAKIIRDYGKQMAGDDCVASRQDED
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| BDBM50498473 |
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| n/a |
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| Name | BDBM50498473 |
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| Synonyms: | CHEMBL1230654 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H20ClNO2 |
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| Mol. Mass. | 353.842 |
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| SMILES | CCC[C@H](C(O)=O)c1c(C)nc2ccc(Cl)cc2c1-c1ccccc1 |r| |
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| Structure | 
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