| Reaction Details |
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 | Report a problem with these data |
| Target | Reverse transcriptase |
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| Ligand | BDBM2469 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1513506 (CHEMBL3611932) |
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| IC50 | 4000±n/a nM |
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| Citation |  Patel, RV; Park, SW Pyrroloaryls and pyrroloheteroaryls: Inhibitors of the HIV fusion/attachment, reverse transcriptase and integrase. Bioorg Med Chem23:5247-63 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Reverse transcriptase |
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| Name: | Reverse transcriptase |
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| Synonyms: | n/a |
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| Type: | Protein |
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| Mol. Mass.: | 29598.37 |
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| Organism: | Human immunodeficiency virus 1 |
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| Description: | Q9WKE8 |
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| Residue: | 254 |
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| Sequence: | PISPITVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKIEKIGPENPYNTPVF
AIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLD
KDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIY
QYMDDLYVGSDLEIEQHRAKIEELRQHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWTV
QPIVLPEKDSWTVN
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| BDBM2469 |
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| n/a |
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| Name | BDBM2469 |
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| Synonyms: | 9-(prop-2-en-1-yl)-2-thia-3,9-diazatricyclo[8.4.0.0^{3,7}]tetradeca-1(10),4,6,11,13-pentaene-2,2,8-trione | Pyrrolobenzothiadiazepine (PBTD) 10h |
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| Type | Small organic molecule |
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| Emp. Form. | C14H12N2O3S |
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| Mol. Mass. | 288.322 |
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| SMILES | C=CCN1c2ccccc2S(=O)(=O)n2cccc2C1=O |
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| Structure | 
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