| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Reverse transcriptase |
|---|
| Ligand | BDBM50052043 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1513506 (CHEMBL3611932) |
|---|
| IC50 | 470±n/a nM |
|---|
| Citation |  Patel, RV; Park, SW Pyrroloaryls and pyrroloheteroaryls: Inhibitors of the HIV fusion/attachment, reverse transcriptase and integrase. Bioorg Med Chem23:5247-63 (2015) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Reverse transcriptase |
|---|
| Name: | Reverse transcriptase |
|---|
| Synonyms: | n/a |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 29598.37 |
|---|
| Organism: | Human immunodeficiency virus 1 |
|---|
| Description: | Q9WKE8 |
|---|
| Residue: | 254 |
|---|
| Sequence: | PISPITVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKIEKIGPENPYNTPVF
AIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLD
KDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIY
QYMDDLYVGSDLEIEQHRAKIEELRQHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWTV
QPIVLPEKDSWTVN
|
|
|
|---|
| BDBM50052043 |
|---|
| n/a |
|---|
| Name | BDBM50052043 |
|---|
| Synonyms: | 5-Ethyl-5-phenyl-6-thia-10b-aza-benzo[e]azulen-4-one | CHEMBL313804 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C20H17NOS |
|---|
| Mol. Mass. | 319.42 |
|---|
| SMILES | CCC1(Sc2ccccc2-n2cccc2C1=O)c1ccccc1 |
|---|
| Structure | 
|
|---|
Search and Browse
