| Reaction Details |
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 | Report a problem with these data |
| Target | D(2) dopamine receptor |
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| Ligand | BDBM50047442 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_62225 |
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| Ki | 2.8±n/a nM |
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| Citation |  Mewshaw, RE; Silverman, LS; Mathew, RM; Kaiser, C; Sherrill, RG; Cheng, M; Tiffany, CW; Karbon, EW; Bailey, MA; Borosky, SA Bridged gamma-carbolines and derivatives possessing selective and combined affinity for 5-HT2 and D2 receptors. J Med Chem36:1488-95 (1993) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| D(2) dopamine receptor |
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| Name: | D(2) dopamine receptor |
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| Synonyms: | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2_RAT | Dopamine D2 receptor | Dopamine2-like | Drd2 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 50931.60 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | P61169 |
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| Residue: | 444 |
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| Sequence: | MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVS
REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTA
SILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQN
ECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPL
KGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPP
SHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMS
RRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNS
AVNPIIYTTFNIEFRKAFMKILHC
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| BDBM50047442 |
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| n/a |
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| Name | BDBM50047442 |
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| Synonyms: | 5-[5-fluoro-9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]-1-phenyl-1-pentanone | CHEMBL37385 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H25FN2O |
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| Mol. Mass. | 376.4665 |
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| SMILES | Fc1ccc2[nH]c3CC4CCC(N4CCCCC(=O)c4ccccc4)c3c2c1 |TLB:13:12:25.6.7:10.9,26:25:12:10.9,5:6:12:10.9| |
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| Structure | 
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