| Reaction Details |
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 | Report a problem with these data |
| Target | C3a anaphylatoxin chemotactic receptor |
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| Ligand | BDBM50499184 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1538088 (CHEMBL3738949) |
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| EC50 | 72±n/a nM |
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| Citation |  Singh, R; Reed, AN; Chu, P; Scully, CC; Yau, MK; Suen, JY; Durek, T; Reid, RC; Fairlie, DP Potent complement C3a receptor agonists derived from oxazole amino acids: Structure-activity relationships. Bioorg Med Chem Lett25:5604-8 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| C3a anaphylatoxin chemotactic receptor |
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| Name: | C3a anaphylatoxin chemotactic receptor |
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| Synonyms: | AZ3B | C3AR | C3AR1 | C3AR_HUMAN | C3R1 | C3a-R | HNFAG09 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 53864.66 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_642034 |
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| Residue: | 482 |
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| Sequence: | MASFSAETNSTDLLSQPWNEPPVILSMVILSLTFLLGLPGNGLVLWVAGLKMQRTVNTIW
FLHLTLADLLCCLSLPFSLAHLALQGQWPYGRFLCKLIPSIIVLNMFASVFLLTAISLDR
CLVVFKPIWCQNHRNVGMACSICGCIWVVAFVMCIPVFVYREIFTTDNHNRCGYKFGLSS
SLDYPDFYGDPLENRSLENIVQPPGEMNDRLDPSSFQTNDHPWTVPTVFQPQTFQRPSAD
SLPRGSARLTSQNLYSNVFKPADVVSPKIPSGFPIEDHETSPLDNSDAFLSTHLKLFPSA
SSNSFYESELPQGFQDYYNLGQFTDDDQVPTPLVAITITRLVVGFLLPSVIMIACYSFIV
FRMQRGRFAKSQSKTFRVAVVVVAVFLVCWTPYHIFGVLSLLTDPETPLGKTLMSWDHVC
IALASANSCFNPFLYALLGKDFRKKARQSIQGILEAAFSEELTRSTHCPSNNVISERNST
TV
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| BDBM50499184 |
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| n/a |
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| Name | BDBM50499184 |
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| Synonyms: | CHEMBL3735993 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H33N7O5 |
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| Mol. Mass. | 511.5734 |
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| SMILES | CC[C@H](C)[C@H](NC(=O)Cc1c[nH]c2ccccc12)c1nc(co1)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O |r| |
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| Structure | 
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