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TargetPeroxisome proliferator-activated receptor alpha
LigandBDBM28699
Substrate/Competitorn/a
Meas. Tech.ChEMBL_153485
EC50 51000±n/a nM
Citation Willson TMCobb JECowan DJWiethe RWCorrea IDPrakash SRBeck KDMoore LBKliewer SALehmann JM The structure-activity relationship between peroxisome proliferator-activated receptor gamma agonism and the antihyperglycemic activity of thiazolidinediones. J Med Chem 39:665-8 (1996) [PubMed]  Article
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Peroxisome proliferator-activated receptor alpha
Name:Peroxisome proliferator-activated receptor alpha
Synonyms:Nuclear receptor subfamily 1 group C member 1 | PPAR-alpha
Type:PROTEIN
Mol. Mass.:52343.28
Organism:Mus musculus
Description:ChEMBL_572395
Residue:468
Sequence:
MVDTESPICPLSPLEADDLESPLSEEFLQEMGNIQEISQSIGEESSGSFGFADYQYLGSC
PGSEGSVITDTLSPASSPSSVSCPVIPASTDESPGSALNIECRICGDKASGYHYGVHACE
GCKGFFRRTIRLKLVYDKCDRSCKIQKKNRNKCQYCRFHKCLSVGMSHNAIRFGRMPRSE
KAKLKAEILTCEHDLKDSETADLKSLGKRIHEAYLKNFNMNKVKARVILAGKTSNNPPFV
IHDMETLCMAEKTLVAKMVANGVEDKEAEVRFFHCCQCMSVETVTELTEFAKAIPGFANL
DLNDQVTLLKYGVYEAIFTMLSSLMNKDGMLIAYGNGFITREFLKNLRKPFCDIMEPKFD
FAMKFNALELDDSDISLFVAAIICCGDRPGLLNIGYIEKLQEGIVHVLKLHLQSNHPDDT
FLFPKLLQKMVDLRQLVTEHAQLVQVIKKTESDAALHPLLQEIYRDMY
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  Blast E-value cutoff:
BDBM28699
n/a
NameBDBM28699
Synonyms:2-(4-chlorophenoxy)-2-methylpropanoic acid | CHEMBL683 | Clofibrate | Clofibrinic acid | clofibric acid
TypeSmall organic molecule
Emp. Form.C10H11ClO3
Mol. Mass.214.646
SMILESCC(C)(Oc1ccc(Cl)cc1)C(O)=O
Structure
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