| Reaction Details |
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 | Report a problem with these data |
| Target | Peptidyl-prolyl cis-trans isomerase A |
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| Ligand | BDBM50500613 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1548721 (CHEMBL3754980) |
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| IC50 | 5.5±n/a nM |
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| Citation |  Yang, S; K R, J; Lim, S; Choi, TG; Kim, JH; Akter, S; Jang, M; Ahn, HJ; Kim, HY; Windisch, MP; Khadka, DB; Zhao, C; Jin, Y; Kang, I; Ha, J; Oh, BC; Kim, M; Kim, SS; Cho, WJ Structure-Based Discovery of Novel Cyclophilin A Inhibitors for the Treatment of Hepatitis C Virus Infections. J Med Chem58:9546-61 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Peptidyl-prolyl cis-trans isomerase A |
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| Name: | Peptidyl-prolyl cis-trans isomerase A |
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| Synonyms: | CYPA | CYPA PPIase | Cyclophilin A | Cyclosporin A-binding protein | PPIA | PPIA_HUMAN | PPIase A | Peptidyl-prolyl cis-trans isomerase A | Rotamase A |
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| Type: | Protein |
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| Mol. Mass.: | 18015.32 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P62937 |
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| Residue: | 165 |
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| Sequence: | MVNPTVFFDIAVDGEPLGRVSFELFADKVPKTAENFRALSTGEKGFGYKGSCFHRIIPGF
MCQGGDFTRHNGTGGKSIYGEKFEDENFILKHTGPGILSMANAGPNTNGSQFFICTAKTE
WLDGKHVVFGKVKEGMNIVEAMERFGSRNGKTSKKITIADCGQLE
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| BDBM50500613 |
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| n/a |
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| Name | BDBM50500613 |
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| Synonyms: | CHEMBL3752642 |
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| Type | Small organic molecule |
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| Emp. Form. | C36H43N3O5 |
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| Mol. Mass. | 597.7437 |
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| SMILES | COc1cc(cc(OC)c1OC)C(N(C(=O)Cc1c[nH]c2ccccc12)c1ccc(cc1)C(C)C)C(=O)NC1CCCCC1 |
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| Structure | 
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