| Reaction Details |
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 | Report a problem with these data |
| Target | Cannabinoid receptor 1 |
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| Ligand | BDBM50500799 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1550698 (CHEMBL3760366) |
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| EC50 | 27±n/a nM |
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| Citation |  Kulkarni, PM; Kulkarni, AR; Korde, A; Tichkule, RB; Laprairie, RB; Denovan-Wright, EM; Zhou, H; Janero, DR; Zvonok, N; Makriyannis, A; Cascio, MG; Pertwee, RG; Thakur, GA Novel Electrophilic and Photoaffinity Covalent Probes for Mapping the Cannabinoid 1 Receptor Allosteric Site(s). J Med Chem59:44-60 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cannabinoid receptor 1 |
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| Name: | Cannabinoid receptor 1 |
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| Synonyms: | Brain-type cannabinoid receptor | CANNABINOID CB1 | CB-R | CB1 | CNR1_MOUSE | Cannabinoid CB1 receptor | Cannabinoid receptor | Cnr1 |
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| Type: | Enzyme |
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| Mol. Mass.: | 52842.52 |
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| Organism: | Mus musculus (Mouse) |
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| Description: | P47746 |
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| Residue: | 473 |
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| Sequence: | MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQE
KMTAGDNSPLVPAGDTTNITEFYNKSLSSFKENEDNIQCGENFMDMECFMILNPSQQLAI
AVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFVDFHV
FHRKDSPNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCL
MWTIAIVIAVLPLLGWNCKKLQSVCSDIFPLIDETYLMFWIGVTSVLLLFIVYAYMYILW
KAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPL
LAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTA
QPLDNSMGDSDCLHKHANNTASMHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
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| BDBM50500799 |
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| n/a |
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| Name | BDBM50500799 |
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| Synonyms: | CHEMBL3758877 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H28N4OS |
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| Mol. Mass. | 432.581 |
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| SMILES | CCc1c([nH]c2ccc(cc12)N=C=S)C(=O)NCCc1ccc(cc1)N1CCCCC1 |
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| Structure | 
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