| Reaction Details |
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 | Report a problem with these data |
| Target | Histamine H3 receptor |
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| Ligand | BDBM50051213 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_86902 (CHEMBL698412) |
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| Ki | 18±n/a nM |
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| Citation |  Stark, H; Purand, K; Ligneau, X; Rouleau, A; Arrang, JM; Garbarg, M; Schwartz, JC; Schunack, W Novel carbamates as potent histamine H3 receptor antagonists with high in vitro and oral in vivo activity. J Med Chem39:1157-63 (1996) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Histamine H3 receptor |
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| Name: | Histamine H3 receptor |
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| Synonyms: | HH3R | HRH3_RAT | Hrh3 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 48607.98 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | n/a |
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| Residue: | 445 |
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| Sequence: | MERAPPDGLMNASGTLAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFV
ADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCAS
SVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGG
SSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAG
PEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVEAGEAALGGGSGGGAA
ASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSL
AIIVSIFGLCWAPYTLLMIIRAACHGRCIPDYWYETSFWLLWANSAVNPVLYPLCHYSFR
RAFTKLLCPQKLKVQPHGSLEQCWK
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| BDBM50051213 |
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| n/a |
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| Name | BDBM50051213 |
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| Synonyms: | CHEMBL278025 | Thiophen-2-ylmethyl-carbamic acid 3-(1H-imidazol-4-yl)-propyl ester |
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| Type | Small organic molecule |
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| Emp. Form. | C12H15N3O2S |
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| Mol. Mass. | 265.331 |
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| SMILES | O=C(NCc1cccs1)OCCCc1cnc[nH]1 |
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| Structure | 
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