| Reaction Details |
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 | Report a problem with these data |
| Target | Neuromedin-K receptor |
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| Ligand | BDBM50052516 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_209699 (CHEMBL811685) |
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| EC50 | 1000±n/a nM |
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| Citation |  Byk, G; Halle, D; Zeltser, I; Bitan, G; Selinger, Z; Gilon, C Synthesis and biological activity of NK-1 selective, N-backbone cyclic analogs of the C-terminal hexapeptide of substance P. J Med Chem39:3174-8 (1996) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Neuromedin-K receptor |
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| Name: | Neuromedin-K receptor |
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| Synonyms: | NK3R_RAT | Neurokinin 3 receptor | Tac3r | Tacr3 |
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| Type: | n/a |
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| Mol. Mass.: | 51128.60 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_10983 |
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| Residue: | 452 |
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| Sequence: | MASVPRGENWTDGTVEVGTHTGNLSSALGVTEWLALQAGNFSSALGLPATTQAPSQVRAN
LTNQFVQPSWRIALWSLAYGLVVAVAVFGNLIVIWIILAHKRMRTVTNYFLVNLAFSDAS
VAAFNTLINFIYGLHSEWYFGANYCRFQNFFPITAVFASIYSMTAIAVDRYMAIIDPLKP
RLSATATKIVIGSIWILAFLLAFPQCLYSKIKVMPGRTLCYVQWPEGPKQHFTYHIIVII
LVYCFPLLIMGVTYTIVGITLWGGEIPGDTCDKYHEQLKAKRKVVKMMIIVVVTFAICWL
PYHVYFILTAIYQQLNRWKYIQQVYLASFWLAMSSTMYNPIIYCCLNKRFRAGFKRAFRW
CPFIQVSSYDELELKTTRFHPTRQSSLYTVSRMESVTVLFDPNDGDPTKSSRKKRAVPRD
PSANGCSHRGSKSASTTSSFISSPYTSVDEYS
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| BDBM50052516 |
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| n/a |
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| Name | BDBM50052516 |
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| Synonyms: | (S)-2-{2-[(3S,6R,9S)-3,6-Dibenzyl-9-(3-guanidino-propyl)-2,5,8,11,15-pentaoxo-1,4,7,10,16pentaaza-cyclodocos-1-yl]-acetylamino}-4-methyl-pentanoic acid ((S)-1-carbamoyl-3-methylsulfanyl-propyl)-amide | CHEMBL431243 |
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| Type | Small organic molecule |
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| Emp. Form. | C48H73N11O8S |
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| Mol. Mass. | 964.227 |
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| SMILES | CSCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)CN1CCCCCCNC(=O)CCCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc2ccccc2)C(=O)N[C@@H](Cc2ccccc2)C1=O)C(N)=O |
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| Structure | 
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