| Reaction Details |
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 | Report a problem with these data |
| Target | D(2) dopamine receptor |
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| Ligand | BDBM50054366 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_62555 (CHEMBL674067) |
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| Ki | >1000±n/a nM |
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| Citation |  López-Rodríguez, ML; Rosado, ML; Benhamú, B; Morcillo, MJ; Sanz, AM; Orensanz, L; Beneitez, ME; Fuentes, JA; Manzanares, J Synthesis and structure-activity relationships of a new model of arylpiperazines. 1. 2-[[4-(o-methoxyphenyl)piperazin-1-yl]methyl]-1, 3-dioxoperhydroimidazo[1,5-alpha]pyridine: a selective 5-HT1A receptor agonist. J Med Chem39:4439-50 (1996) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| D(2) dopamine receptor |
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| Name: | D(2) dopamine receptor |
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| Synonyms: | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2_RAT | Dopamine D2 receptor | Dopamine2-like | Drd2 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 50931.60 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | P61169 |
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| Residue: | 444 |
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| Sequence: | MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVS
REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTA
SILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQN
ECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPL
KGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPP
SHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMS
RRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNS
AVNPIIYTTFNIEFRKAFMKILHC
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| BDBM50054366 |
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| n/a |
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| Name | BDBM50054366 |
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| Synonyms: | 2-[4-(4-Phenyl-piperazin-1-yl)-butyl]-tetrahydro-imidazo[1,5-a]pyridine-1,3-dione | CHEMBL42404 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H30N4O2 |
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| Mol. Mass. | 370.4885 |
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| SMILES | Oc1c2CCCCn2c(=O)n1CCCCN1CCN(CC1)c1ccccc1 |
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| Structure | 
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