Compile Data Set for Download or QSAR

Found 221 hits with Last Name = 'manzanares' and Initial = 'j'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50164462 (2-[4-(4-Naphthalen-1-yl-piperazin-1-yl)-butyl]-hex...) Show SMILES O=C1CN(CCCCN2CCN(CC2)c2cccc3ccccc23)C(=O)C2CCCN12 Show InChI InChI=1S/C25H32N4O2/c30-24-19-28(25(31)23-11-6-14-29(23)24)13-4-3-12-26-15-17-27(18-16-26)22-10-5-8-20-7-1-2-9-21(20)22/h1-2,5,7-10,23H,3-4,6,11-19H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat cerebral cortex membranes				J Med Chem 48: 2548-2558 (2005) Article DOI: 10.1021/jm048999e BindingDB Entry DOI: 10.7270/Q23F4PNB
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM82517 (2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...) Show SMILES COc1ccccc1N1CCN(CCCCN2C(=O)c3ccccc3C2=O)CC1 Show InChI InChI=1S/C23H27N3O3/c1-29-21-11-5-4-10-20(21)25-16-14-24(15-17-25)12-6-7-13-26-22(27)18-8-2-3-9-19(18)23(26)28/h2-5,8-11H,6-7,12-17H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense Curated by ChEMBL					Assay Description Binding affinity towards rat 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand.				J Med Chem 39: 4439-50 (1996) Article DOI: 10.1021/jm960416g BindingDB Entry DOI: 10.7270/Q2WS8SBN
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50016825 (CHEMBL421130) Show SMILES O=C1C2CCCN2C(=O)N1CCCCN1CCN(CC1)c1cccc2[nH]cnc12 Show InChI InChI=1S/C21H28N6O2/c28-20-18-7-4-10-26(18)21(29)27(20)9-2-1-8-24-11-13-25(14-12-24)17-6-3-5-16-19(17)23-15-22-16/h3,5-6,15,18H,1-2,4,7-14H2,(H,22,23)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat cerebral cortex membranes				J Med Chem 48: 2548-2558 (2005) Article DOI: 10.1021/jm048999e BindingDB Entry DOI: 10.7270/Q23F4PNB
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50095801 (2-{4-[4-(2-Butoxy-phenyl)-piperazin-1-yl]-butyl}-t...) Show SMILES CCCCOc1ccccc1N1CCN(CCCCn2c(O)c3CCCCn3c2=O)CC1 Show InChI InChI=1S/C25H38N4O3/c1-2-3-20-32-23-12-5-4-10-21(23)27-18-16-26(17-19-27)13-8-9-15-29-24(30)22-11-6-7-14-28(22)25(29)31/h4-5,10,12,30H,2-3,6-9,11,13-20H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense Curated by ChEMBL					Assay Description In vitro binding affinity towards 5-hydroxytryptamine 1A receptor was determined using radioligand [3H]-8-OH-DPAT				J Med Chem 44: 186-97 (2001) BindingDB Entry DOI: 10.7270/Q2RN38MH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50080166 (2-{4-[4-(1H-Benzoimidazol-4-yl)-piperazin-1-yl]-bu...) Show SMILES Oc1c2CCCn2c(=O)n1CCCCN1CCN(CC1)c1cccc2[nH]cnc12 Show InChI InChI=1S/C21H28N6O2/c28-20-18-7-4-10-26(18)21(29)27(20)9-2-1-8-24-11-13-25(14-12-24)17-6-3-5-16-19(17)23-15-22-16/h3,5-6,15,28H,1-2,4,7-14H2,(H,22,23)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat cerebral cortex membranes				J Med Chem 48: 2548-2558 (2005) Article DOI: 10.1021/jm048999e BindingDB Entry DOI: 10.7270/Q23F4PNB
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50016822 (CHEMBL33150) Show SMILES O=C1C2CCCN2C(=O)N1CCCCN1CCN(CC1)c1cccc2ccccc12 Show InChI InChI=1S/C24H30N4O2/c29-23-22-11-6-14-27(22)24(30)28(23)13-4-3-12-25-15-17-26(18-16-25)21-10-5-8-19-7-1-2-9-20(19)21/h1-2,5,7-10,22H,3-4,6,11-18H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat cerebral cortex membranes				J Med Chem 48: 2548-2558 (2005) Article DOI: 10.1021/jm048999e BindingDB Entry DOI: 10.7270/Q23F4PNB
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50126474 (2-[4-(4-Naphthalen-1-yl-piperazin-1-yl)-butyl]-tet...) Show SMILES Oc1c2CCCn2c(=O)n1CCCCN1CCN(CC1)c1cccc2ccccc12 Show InChI InChI=1S/C24H30N4O2/c29-23-22-11-6-14-27(22)24(30)28(23)13-4-3-12-25-15-17-26(18-16-25)21-10-5-8-19-7-1-2-9-20(19)21/h1-2,5,7-10,29H,3-4,6,11-18H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense Curated by ChEMBL					Assay Description Binding affinity of the compound towards 5-HT 1A receptor in rat cerebral cortex membranes using [3H]-8-OH-DPAT as radioligand				Bioorg Med Chem Lett 13: 1429-32 (2003) BindingDB Entry DOI: 10.7270/Q2BV7FZX
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50054393 (2-{4-[4-(3-Trifluoromethyl-phenyl)-piperazin-1-yl]...) Show SMILES Oc1c2CCCn2c(=O)n1CCCCN1CCN(CC1)c1cccc(c1)C(F)(F)F Show InChI InChI=1S/C21H27F3N4O2/c22-21(23,24)16-5-3-6-17(15-16)26-13-11-25(12-14-26)8-1-2-9-28-19(29)18-7-4-10-27(18)20(28)30/h3,5-6,15,29H,1-2,4,7-14H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense Curated by ChEMBL					Assay Description Binding affinity towards rat 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand.				J Med Chem 39: 4439-50 (1996) Article DOI: 10.1021/jm960416g BindingDB Entry DOI: 10.7270/Q2WS8SBN
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50126474 (2-[4-(4-Naphthalen-1-yl-piperazin-1-yl)-butyl]-tet...) Show SMILES Oc1c2CCCn2c(=O)n1CCCCN1CCN(CC1)c1cccc2ccccc12 Show InChI InChI=1S/C24H30N4O2/c29-23-22-11-6-14-27(22)24(30)28(23)13-4-3-12-25-15-17-26(18-16-25)21-10-5-8-19-7-1-2-9-20(19)21/h1-2,5,7-10,29H,3-4,6,11-18H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat cerebral cortex membranes				J Med Chem 48: 2548-2558 (2005) Article DOI: 10.1021/jm048999e BindingDB Entry DOI: 10.7270/Q23F4PNB
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50164454 ((S)-2-((S)-2-Methyl-4-naphthalen-1-yl-piperazin-1-...) Show SMILES C[C@H]1CN(CCN1CN1CC(=O)N2CCC[C@H]2C1=O)c1cccc2ccccc12 Show InChI InChI=1S/C23H28N4O2/c1-17-14-24(20-9-4-7-18-6-2-3-8-19(18)20)12-13-25(17)16-26-15-22(28)27-11-5-10-21(27)23(26)29/h2-4,6-9,17,21H,5,10-16H2,1H3/t17-,21-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat cerebral cortex membranes				J Med Chem 48: 2548-2558 (2005) Article DOI: 10.1021/jm048999e BindingDB Entry DOI: 10.7270/Q23F4PNB
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50016826 (CHEMBL34288) Show SMILES O=C1C2CCCCN2C(=O)N1CN1CCN(CC1)c1cccc2OC=COCc12 |c:27| Show InChI InChI=1S/C21H26N4O4/c26-20-18-4-1-2-7-24(18)21(27)25(20)15-22-8-10-23(11-9-22)17-5-3-6-19-16(17)14-28-12-13-29-19/h3,5-6,12-13,18H,1-2,4,7-11,14-15H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat cerebral cortex membranes				J Med Chem 48: 2548-2558 (2005) Article DOI: 10.1021/jm048999e BindingDB Entry DOI: 10.7270/Q23F4PNB
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50095818 (2-{4-[4-(3-Trifluoromethyl-phenyl)-piperazin-1-yl]...) Show SMILES FC(F)(F)c1cccc(c1)N1CCN(CCCCN2CC(=O)N3CCCC3C2=O)CC1 Show InChI InChI=1S/C22H29F3N4O2/c23-22(24,25)17-5-3-6-18(15-17)27-13-11-26(12-14-27)8-1-2-9-28-16-20(30)29-10-4-7-19(29)21(28)31/h3,5-6,15,19H,1-2,4,7-14,16H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	3.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense Curated by ChEMBL					Assay Description In vitro binding affinity towards 5-hydroxytryptamine 1A receptor was determined using radioligand [3H]-8-OH-DPAT				J Med Chem 44: 186-97 (2001) BindingDB Entry DOI: 10.7270/Q2RN38MH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50095817 (2-{4-[4-(1,3-Dioxo-tetrahydro-pyrrolo[1,2-c]imidaz...) Show SMILES Oc1c2CCCn2c(=O)n1CCCCN1CCN(CC1)c1ccccc1C#N Show InChI InChI=1S/C21H27N5O2/c22-16-17-6-1-2-7-18(17)24-14-12-23(13-15-24)9-3-4-10-26-20(27)19-8-5-11-25(19)21(26)28/h1-2,6-7,27H,3-5,8-15H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense Curated by ChEMBL					Assay Description In vitro binding affinity towards 5-hydroxytryptamine 1A receptor was determined using radioligand [3H]-8-OH-DPAT				J Med Chem 44: 186-97 (2001) BindingDB Entry DOI: 10.7270/Q2RN38MH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50054392 (2-{3-[4-(3-Trifluoromethyl-phenyl)-piperazin-1-yl]...) Show SMILES Oc1c2CCCn2c(=O)n1CCCN1CCN(CC1)c1cccc(c1)C(F)(F)F Show InChI InChI=1S/C20H25F3N4O2/c21-20(22,23)15-4-1-5-16(14-15)25-12-10-24(11-13-25)7-3-9-27-18(28)17-6-2-8-26(17)19(27)29/h1,4-5,14,28H,2-3,6-13H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense Curated by ChEMBL					Assay Description Binding affinity towards rat 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand.				J Med Chem 39: 4439-50 (1996) Article DOI: 10.1021/jm960416g BindingDB Entry DOI: 10.7270/Q2WS8SBN
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50095800 (2-{4-[4-(1,3-Dioxo-tetrahydro-pyrrolo[1,2-c]imidaz...) Show SMILES CCCOC(=O)c1ccccc1N1CCN(CCCCn2c(O)c3CCCn3c2=O)CC1 Show InChI InChI=1S/C24H34N4O4/c1-2-18-32-23(30)19-8-3-4-9-20(19)26-16-14-25(15-17-26)11-5-6-12-28-22(29)21-10-7-13-27(21)24(28)31/h3-4,8-9,29H,2,5-7,10-18H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense Curated by ChEMBL					Assay Description In vitro binding affinity towards 5-hydroxytryptamine 1A receptor was determined using radioligand [3H]-8-OH-DPAT				J Med Chem 44: 186-97 (2001) BindingDB Entry DOI: 10.7270/Q2RN38MH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50095816 (2-{4-[4-(3-Bromo-phenyl)-piperazin-1-yl]-butyl}-te...) Show SMILES Oc1c2CCCCn2c(=O)n1CCCCN1CCN(CC1)c1cccc(Br)c1 Show InChI InChI=1S/C21H29BrN4O2/c22-17-6-5-7-18(16-17)24-14-12-23(13-15-24)9-3-4-11-26-20(27)19-8-1-2-10-25(19)21(26)28/h5-7,16,27H,1-4,8-15H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense Curated by ChEMBL					Assay Description In vitro binding affinity towards 5-hydroxytryptamine 1A receptor was determined using radioligand [3H]-8-OH-DPAT				J Med Chem 44: 186-97 (2001) BindingDB Entry DOI: 10.7270/Q2RN38MH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50126481 (2-[4-(1H-Benzoimidazol-4-yl)-piperazin-1-ylmethyl]...) Show SMILES Oc1c2CCCn2c(=O)n1CN1CCN(CC1)c1cccc2[nH]cnc12 Show InChI InChI=1S/C18H22N6O2/c25-17-15-5-2-6-23(15)18(26)24(17)12-21-7-9-22(10-8-21)14-4-1-3-13-16(14)20-11-19-13/h1,3-4,11,25H,2,5-10,12H2,(H,19,20)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense Curated by ChEMBL					Assay Description Binding affinity of the compound towards 5-HT 1A receptor in rat cerebral cortex membranes using [3H]-8-OH-DPAT as radioligand				Bioorg Med Chem Lett 13: 1429-32 (2003) BindingDB Entry DOI: 10.7270/Q2BV7FZX
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50126475 (2-(4-Naphthalen-1-yl-piperazin-1-ylmethyl)-hexahyd...) Show SMILES O=C1CN(CN2CCN(CC2)c2cccc3ccccc23)C(=O)C2CCCN12 Show InChI InChI=1S/C22H26N4O2/c27-21-15-25(22(28)20-9-4-10-26(20)21)16-23-11-13-24(14-12-23)19-8-3-6-17-5-1-2-7-18(17)19/h1-3,5-8,20H,4,9-16H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense Curated by ChEMBL					Assay Description Binding affinity of the compound towards 5-HT 1A receptor in rat cerebral cortex membranes using [3H]-8-OH-DPAT as radioligand				Bioorg Med Chem Lett 13: 1429-32 (2003) BindingDB Entry DOI: 10.7270/Q2BV7FZX
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50023228 (CHEMBL33258) Show SMILES O=C1C2CCCN2C(=O)N1CN1CCN(CC1)c1cccc2[nH]cnc12 Show InChI InChI=1S/C18H22N6O2/c25-17-15-5-2-6-23(15)18(26)24(17)12-21-7-9-22(10-8-21)14-4-1-3-13-16(14)20-11-19-13/h1,3-4,11,15H,2,5-10,12H2,(H,19,20)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	4.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat cerebral cortex membranes				J Med Chem 48: 2548-2558 (2005) Article DOI: 10.1021/jm048999e BindingDB Entry DOI: 10.7270/Q23F4PNB
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50126481 (2-[4-(1H-Benzoimidazol-4-yl)-piperazin-1-ylmethyl]...) Show SMILES Oc1c2CCCn2c(=O)n1CN1CCN(CC1)c1cccc2[nH]cnc12 Show InChI InChI=1S/C18H22N6O2/c25-17-15-5-2-6-23(15)18(26)24(17)12-21-7-9-22(10-8-21)14-4-1-3-13-16(14)20-11-19-13/h1,3-4,11,25H,2,5-10,12H2,(H,19,20)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat cerebral cortex membranes				J Med Chem 48: 2548-2558 (2005) Article DOI: 10.1021/jm048999e BindingDB Entry DOI: 10.7270/Q23F4PNB
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50054387 (2-{3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-propyl}...) Show SMILES COc1ccccc1N1CCN(CCCn2c(O)c3CCCCn3c2=O)CC1 Show InChI InChI=1S/C21H30N4O3/c1-28-19-9-3-2-7-17(19)23-15-13-22(14-16-23)10-6-12-25-20(26)18-8-4-5-11-24(18)21(25)27/h2-3,7,9,26H,4-6,8,10-16H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense Curated by ChEMBL					Assay Description Binding affinity towards rat 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand.				J Med Chem 39: 4439-50 (1996) Article DOI: 10.1021/jm960416g BindingDB Entry DOI: 10.7270/Q2WS8SBN
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50164450 ((S)-2-(4-Naphthalen-1-yl-piperazin-1-ylmethyl)-hex...) Show SMILES O=C1CN(CN2CCN(CC2)c2cccc3ccccc23)C(=O)[C@@H]2CCCN12 Show InChI InChI=1S/C22H26N4O2/c27-21-15-25(22(28)20-9-4-10-26(20)21)16-23-11-13-24(14-12-23)19-8-3-6-17-5-1-2-7-18(17)19/h1-3,5-8,20H,4,9-16H2/t20-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat cerebral cortex membranes				J Med Chem 48: 2548-2558 (2005) Article DOI: 10.1021/jm048999e BindingDB Entry DOI: 10.7270/Q23F4PNB
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50164455 ((R)-2-[4-((R)-2-Methyl-4-naphthalen-1-yl-piperazin...) Show SMILES C[C@@H]1CN(CCN1CCCCN1CC(=O)N2CCCC2C1=O)c1cccc2ccccc12 Show InChI InChI=1S/C26H34N4O2/c1-20-18-28(23-11-6-9-21-8-2-3-10-22(21)23)17-16-27(20)13-4-5-14-29-19-25(31)30-15-7-12-24(30)26(29)32/h2-3,6,8-11,20,24H,4-5,7,12-19H2,1H3/t20-,24?/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat cerebral cortex membranes				J Med Chem 48: 2548-2558 (2005) Article DOI: 10.1021/jm048999e BindingDB Entry DOI: 10.7270/Q23F4PNB
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50054359 (2-{3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-propyl}...) Show SMILES COc1ccccc1N1CCN(CCCn2c(O)c3CCCn3c2=O)CC1 Show InChI InChI=1S/C20H28N4O3/c1-27-18-8-3-2-6-16(18)22-14-12-21(13-15-22)9-5-11-24-19(25)17-7-4-10-23(17)20(24)26/h2-3,6,8,25H,4-5,7,9-15H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense Curated by ChEMBL					Assay Description Binding affinity towards rat 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand.				J Med Chem 39: 4439-50 (1996) Article DOI: 10.1021/jm960416g BindingDB Entry DOI: 10.7270/Q2WS8SBN
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50164463 ((R)-2-(4-Naphthalen-1-yl-piperazin-1-ylmethyl)-hex...) Show SMILES O=C1CN(CN2CCN(CC2)c2cccc3ccccc23)C(=O)[C@H]2CCCN12 Show InChI InChI=1S/C22H26N4O2/c27-21-15-25(22(28)20-9-4-10-26(20)21)16-23-11-13-24(14-12-23)19-8-3-6-17-5-1-2-7-18(17)19/h1-3,5-8,20H,4,9-16H2/t20-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat cerebral cortex membranes				J Med Chem 48: 2548-2558 (2005) Article DOI: 10.1021/jm048999e BindingDB Entry DOI: 10.7270/Q23F4PNB
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50054395 (2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...) Show SMILES COc1ccccc1N1CCN(CCCCn2c(O)c3CCCn3c2=O)CC1 Show InChI InChI=1S/C21H30N4O3/c1-28-19-9-3-2-7-17(19)23-15-13-22(14-16-23)10-4-5-11-25-20(26)18-8-6-12-24(18)21(25)27/h2-3,7,9,26H,4-6,8,10-16H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense Curated by ChEMBL					Assay Description Binding affinity towards rat 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand.				J Med Chem 39: 4439-50 (1996) Article DOI: 10.1021/jm960416g BindingDB Entry DOI: 10.7270/Q2WS8SBN
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50126477 (2-(4-Naphthalen-1-yl-piperazin-1-ylmethyl)-tetrahy...) Show SMILES Oc1c2CCCCn2c(=O)n1CN1CCN(CC1)c1cccc2ccccc12 Show InChI InChI=1S/C22H26N4O2/c27-21-20-9-3-4-11-25(20)22(28)26(21)16-23-12-14-24(15-13-23)19-10-5-7-17-6-1-2-8-18(17)19/h1-2,5-8,10,27H,3-4,9,11-16H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense Curated by ChEMBL					Assay Description Binding affinity of the compound towards 5-HT 1A receptor in rat cerebral cortex membranes using [3H]-8-OH-DPAT as radioligand				Bioorg Med Chem Lett 13: 1429-32 (2003) BindingDB Entry DOI: 10.7270/Q2BV7FZX
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50126477 (2-(4-Naphthalen-1-yl-piperazin-1-ylmethyl)-tetrahy...) Show SMILES Oc1c2CCCCn2c(=O)n1CN1CCN(CC1)c1cccc2ccccc12 Show InChI InChI=1S/C22H26N4O2/c27-21-20-9-3-4-11-25(20)22(28)26(21)16-23-12-14-24(15-13-23)19-10-5-7-17-6-1-2-8-18(17)19/h1-2,5-8,10,27H,3-4,9,11-16H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat cerebral cortex membranes				J Med Chem 48: 2548-2558 (2005) Article DOI: 10.1021/jm048999e BindingDB Entry DOI: 10.7270/Q23F4PNB
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50016824 (CHEMBL445055) Show SMILES O=C1C2CCCCN2C(=O)N1CN1CCN(CC1)c1cccc2ccccc12 Show InChI InChI=1S/C22H26N4O2/c27-21-20-9-3-4-11-25(20)22(28)26(21)16-23-12-14-24(15-13-23)19-10-5-7-17-6-1-2-8-18(17)19/h1-2,5-8,10,20H,3-4,9,11-16H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat cerebral cortex membranes				J Med Chem 48: 2548-2558 (2005) Article DOI: 10.1021/jm048999e BindingDB Entry DOI: 10.7270/Q23F4PNB
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50054391 (2-{3-[4-(3-Trifluoromethyl-phenyl)-piperazin-1-yl]...) Show SMILES Oc1c2CCCCn2c(=O)n1CCCN1CCN(CC1)c1cccc(c1)C(F)(F)F Show InChI InChI=1S/C21H27F3N4O2/c22-21(23,24)16-5-3-6-17(15-16)26-13-11-25(12-14-26)8-4-10-28-19(29)18-7-1-2-9-27(18)20(28)30/h3,5-6,15,29H,1-2,4,7-14H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense Curated by ChEMBL					Assay Description Binding affinity towards rat 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand.				J Med Chem 39: 4439-50 (1996) Article DOI: 10.1021/jm960416g BindingDB Entry DOI: 10.7270/Q2WS8SBN
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50023227 (CHEMBL2113057) Show SMILES O=C1CN(CCCCN2CCN(CC2)c2cccc3OC=COCc23)C(=O)C2CCCN12 |c:21| Show InChI InChI=1S/C24H32N4O4/c29-23-17-27(24(30)21-6-4-10-28(21)23)9-2-1-8-25-11-13-26(14-12-25)20-5-3-7-22-19(20)18-31-15-16-32-22/h3,5,7,15-16,21H,1-2,4,6,8-14,17-18H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat cerebral cortex membranes				J Med Chem 48: 2548-2558 (2005) Article DOI: 10.1021/jm048999e BindingDB Entry DOI: 10.7270/Q23F4PNB
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50451842 (CHEMBL2113339) Show SMILES O=C1C2CCCCN2C(=O)N1CN1CCN(CC1)c1cccc2OCCOCc12 Show InChI InChI=1S/C21H28N4O4/c26-20-18-4-1-2-7-24(18)21(27)25(20)15-22-8-10-23(11-9-22)17-5-3-6-19-16(17)14-28-12-13-29-19/h3,5-6,18H,1-2,4,7-15H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	6.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense Curated by ChEMBL					Assay Description Binding affinity of the compound towards 5-HT 1A receptor in rat cerebral cortex membranes using [3H]-8-OH-DPAT as radioligand				Bioorg Med Chem Lett 13: 1429-32 (2003) BindingDB Entry DOI: 10.7270/Q2BV7FZX
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50164456 ((S)-2-((R)-2-Methyl-4-naphthalen-1-yl-piperazin-1-...) Show SMILES C[C@@H]1CN(CCN1CN1CC(=O)N2CCC[C@H]2C1=O)c1cccc2ccccc12 Show InChI InChI=1S/C23H28N4O2/c1-17-14-24(20-9-4-7-18-6-2-3-8-19(18)20)12-13-25(17)16-26-15-22(28)27-11-5-10-21(27)23(26)29/h2-4,6-9,17,21H,5,10-16H2,1H3/t17-,21+/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat cerebral cortex membranes				J Med Chem 48: 2548-2558 (2005) Article DOI: 10.1021/jm048999e BindingDB Entry DOI: 10.7270/Q23F4PNB
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50164458 ((R)-2-((S)-2-Methyl-4-naphthalen-1-yl-piperazin-1-...) Show SMILES C[C@H]1CN(CCN1CN1CC(=O)N2CCC[C@@H]2C1=O)c1cccc2ccccc12 Show InChI InChI=1S/C23H28N4O2/c1-17-14-24(20-9-4-7-18-6-2-3-8-19(18)20)12-13-25(17)16-26-15-22(28)27-11-5-10-21(27)23(26)29/h2-4,6-9,17,21H,5,10-16H2,1H3/t17-,21+/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat cerebral cortex membranes				J Med Chem 48: 2548-2558 (2005) Article DOI: 10.1021/jm048999e BindingDB Entry DOI: 10.7270/Q23F4PNB
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50095829 (2-{4-[4-(2-Butoxy-phenyl)-piperazin-1-yl]-butyl}-h...) Show SMILES CCCCOc1ccccc1N1CCN(CCCCN2CC(=O)N3CCCC3C2=O)CC1 Show InChI InChI=1S/C25H38N4O3/c1-2-3-19-32-23-11-5-4-9-21(23)27-17-15-26(16-18-27)12-6-7-13-28-20-24(30)29-14-8-10-22(29)25(28)31/h4-5,9,11,22H,2-3,6-8,10,12-20H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	6.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense Curated by ChEMBL					Assay Description In vitro binding affinity towards 5-hydroxytryptamine 1A receptor was determined using radioligand [3H]-8-OH-DPAT				J Med Chem 44: 186-97 (2001) BindingDB Entry DOI: 10.7270/Q2RN38MH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50126475 (2-(4-Naphthalen-1-yl-piperazin-1-ylmethyl)-hexahyd...) Show SMILES O=C1CN(CN2CCN(CC2)c2cccc3ccccc23)C(=O)C2CCCN12 Show InChI InChI=1S/C22H26N4O2/c27-21-15-25(22(28)20-9-4-10-26(20)21)16-23-11-13-24(14-12-23)19-8-3-6-17-5-1-2-7-18(17)19/h1-3,5-8,20H,4,9-16H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat cerebral cortex membranes				J Med Chem 48: 2548-2558 (2005) Article DOI: 10.1021/jm048999e BindingDB Entry DOI: 10.7270/Q23F4PNB
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50054354 (2-{4-[4-(3-Chloro-phenyl)-piperazin-1-yl]-butyl}-t...) Show SMILES Oc1c2CCCCn2c(=O)n1CCCCN1CCN(CC1)c1cccc(Cl)c1 Show InChI InChI=1S/C21H29ClN4O2/c22-17-6-5-7-18(16-17)24-14-12-23(13-15-24)9-3-4-11-26-20(27)19-8-1-2-10-25(19)21(26)28/h5-7,16,27H,1-4,8-15H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense Curated by ChEMBL					Assay Description Binding affinity towards rat 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand.				J Med Chem 39: 4439-50 (1996) Article DOI: 10.1021/jm960416g BindingDB Entry DOI: 10.7270/Q2WS8SBN
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50164462 (2-[4-(4-Naphthalen-1-yl-piperazin-1-yl)-butyl]-hex...) Show SMILES O=C1CN(CCCCN2CCN(CC2)c2cccc3ccccc23)C(=O)C2CCCN12 Show InChI InChI=1S/C25H32N4O2/c30-24-19-28(25(31)23-11-6-14-29(23)24)13-4-3-12-26-15-17-27(18-16-26)22-10-5-8-20-7-1-2-9-21(20)22/h1-2,5,7-10,23H,3-4,6,11-19H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of [3H]prazosin binding to Alpha-1 adrenergic receptor in rat cerebral cortex membranes				J Med Chem 48: 2548-2558 (2005) Article DOI: 10.1021/jm048999e BindingDB Entry DOI: 10.7270/Q23F4PNB
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50095803 (2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...) Show SMILES COc1ccccc1N1CCN(CCCCN2CC(=O)N3CCCC3C2=O)CC1 Show InChI InChI=1S/C22H32N4O3/c1-29-20-9-3-2-7-18(20)24-15-13-23(14-16-24)10-4-5-11-25-17-21(27)26-12-6-8-19(26)22(25)28/h2-3,7,9,19H,4-6,8,10-17H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	8.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense Curated by ChEMBL					Assay Description In vitro binding affinity towards 5-hydroxytryptamine 1A receptor was determined using radioligand [3H]-8-OH-DPAT				J Med Chem 44: 186-97 (2001) BindingDB Entry DOI: 10.7270/Q2RN38MH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50054362 (2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...) Show SMILES COc1ccccc1N1CCN(CCCCn2c(O)c3CCCCn3c2=O)CC1 Show InChI InChI=1S/C22H32N4O3/c1-29-20-10-3-2-8-18(20)24-16-14-23(15-17-24)11-6-7-13-26-21(27)19-9-4-5-12-25(19)22(26)28/h2-3,8,10,27H,4-7,9,11-17H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense Curated by ChEMBL					Assay Description Binding affinity towards rat 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand.				J Med Chem 39: 4439-50 (1996) Article DOI: 10.1021/jm960416g BindingDB Entry DOI: 10.7270/Q2WS8SBN
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A (RAT)	BDBM50164450 ((S)-2-(4-Naphthalen-1-yl-piperazin-1-ylmethyl)-hex...) Show SMILES O=C1CN(CN2CCN(CC2)c2cccc3ccccc23)C(=O)[C@@H]2CCCN12 Show InChI InChI=1S/C22H26N4O2/c27-21-15-25(22(28)20-9-4-10-26(20)21)16-23-11-13-24(14-12-23)19-8-3-6-17-5-1-2-7-18(17)19/h1-3,5-8,20H,4,9-16H2/t20-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of [3H]LY-278584 binding to 5-hydroxytryptamine 3 receptor in rat cerebral cortex membranes				J Med Chem 48: 2548-2558 (2005) Article DOI: 10.1021/jm048999e BindingDB Entry DOI: 10.7270/Q23F4PNB
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50023226 (CHEMBL34287) Show SMILES O=C1C2CCCCN2C(=O)N1CN1CCN(CC1)c1cccc2OCCOc12 Show InChI InChI=1S/C20H26N4O4/c25-19-16-4-1-2-7-23(16)20(26)24(19)14-21-8-10-22(11-9-21)15-5-3-6-17-18(15)28-13-12-27-17/h3,5-6,16H,1-2,4,7-14H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	9.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat cerebral cortex membranes				J Med Chem 48: 2548-2558 (2005) Article DOI: 10.1021/jm048999e BindingDB Entry DOI: 10.7270/Q23F4PNB
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50126480 (2-[4-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)-piperazin...) Show SMILES Oc1c2CCCCn2c(=O)n1CN1CCN(CC1)c1cccc2OCCOc12 Show InChI InChI=1S/C20H26N4O4/c25-19-16-4-1-2-7-23(16)20(26)24(19)14-21-8-10-22(11-9-21)15-5-3-6-17-18(15)28-13-12-27-17/h3,5-6,25H,1-2,4,7-14H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	9.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense Curated by ChEMBL					Assay Description Binding affinity of the compound towards 5-HT 1A receptor in rat cerebral cortex membranes using [3H]-8-OH-DPAT as radioligand				Bioorg Med Chem Lett 13: 1429-32 (2003) BindingDB Entry DOI: 10.7270/Q2BV7FZX
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50164457 ((R)-2-((R)-2-Methyl-4-naphthalen-1-yl-piperazin-1-...) Show SMILES C[C@@H]1CN(CCN1CN1CC(=O)N2CCC[C@@H]2C1=O)c1cccc2ccccc12 Show InChI InChI=1S/C23H28N4O2/c1-17-14-24(20-9-4-7-18-6-2-3-8-19(18)20)12-13-25(17)16-26-15-22(28)27-11-5-10-21(27)23(26)29/h2-4,6-9,17,21H,5,10-16H2,1H3/t17-,21-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat cerebral cortex membranes				J Med Chem 48: 2548-2558 (2005) Article DOI: 10.1021/jm048999e BindingDB Entry DOI: 10.7270/Q23F4PNB
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50054355 (2-{4-[4-(3-Trifluoromethyl-phenyl)-piperazin-1-yl]...) Show SMILES Oc1c2CCCCn2c(=O)n1CCCCN1CCN(CC1)c1cccc(c1)C(F)(F)F Show InChI InChI=1S/C22H29F3N4O2/c23-22(24,25)17-6-5-7-18(16-17)27-14-12-26(13-15-27)9-3-4-11-29-20(30)19-8-1-2-10-28(19)21(29)31/h5-7,16,30H,1-4,8-15H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense Curated by ChEMBL					Assay Description Binding affinity towards rat 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand.				J Med Chem 39: 4439-50 (1996) Article DOI: 10.1021/jm960416g BindingDB Entry DOI: 10.7270/Q2WS8SBN
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50126476 (2-(4-Naphthalen-1-yl-piperazin-1-ylmethyl)-tetrahy...) Show SMILES Oc1c2CCCn2c(=O)n1CN1CCN(CC1)c1cccc2ccccc12 Show InChI InChI=1S/C21H24N4O2/c26-20-19-9-4-10-24(19)21(27)25(20)15-22-11-13-23(14-12-22)18-8-3-6-16-5-1-2-7-17(16)18/h1-3,5-8,26H,4,9-15H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense Curated by ChEMBL					Assay Description Binding affinity of the compound towards 5-HT 1A receptor in rat cerebral cortex membranes using [3H]-8-OH-DPAT as radioligand				Bioorg Med Chem Lett 13: 1429-32 (2003) BindingDB Entry DOI: 10.7270/Q2BV7FZX
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50016823 (CHEMBL430914) Show SMILES O=C1C2CCCN2C(=O)N1CN1CCN(CC1)c1cccc2ccccc12 Show InChI InChI=1S/C21H24N4O2/c26-20-19-9-4-10-24(19)21(27)25(20)15-22-11-13-23(14-12-22)18-8-3-6-16-5-1-2-7-17(16)18/h1-3,5-8,19H,4,9-15H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat cerebral cortex membranes				J Med Chem 48: 2548-2558 (2005) Article DOI: 10.1021/jm048999e BindingDB Entry DOI: 10.7270/Q23F4PNB
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50126476 (2-(4-Naphthalen-1-yl-piperazin-1-ylmethyl)-tetrahy...) Show SMILES Oc1c2CCCn2c(=O)n1CN1CCN(CC1)c1cccc2ccccc12 Show InChI InChI=1S/C21H24N4O2/c26-20-19-9-4-10-24(19)21(27)25(20)15-22-11-13-23(14-12-22)18-8-3-6-16-5-1-2-7-17(16)18/h1-3,5-8,26H,4,9-15H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	10.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat cerebral cortex membranes				J Med Chem 48: 2548-2558 (2005) Article DOI: 10.1021/jm048999e BindingDB Entry DOI: 10.7270/Q23F4PNB
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50095810 (2-{3-[4-(2-Butoxy-phenyl)-piperazin-1-yl]-propyl}-...) Show SMILES CCCCOc1ccccc1N1CCN(CCCn2c(O)c3CCCn3c2=O)CC1 Show InChI InChI=1S/C23H34N4O3/c1-2-3-18-30-21-10-5-4-8-19(21)25-16-14-24(15-17-25)11-7-13-27-22(28)20-9-6-12-26(20)23(27)29/h4-5,8,10,28H,2-3,6-7,9,11-18H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense Curated by ChEMBL					Assay Description In vitro binding affinity towards 5-hydroxytryptamine 1A receptor was determined using radioligand [3H]-8-OH-DPAT				J Med Chem 44: 186-97 (2001) BindingDB Entry DOI: 10.7270/Q2RN38MH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50054351 (2-{4-[4-(3-Chloro-phenyl)-piperazin-1-yl]-butyl}-t...) Show SMILES Oc1c2CCCn2c(=O)n1CCCCN1CCN(CC1)c1cccc(Cl)c1 Show InChI InChI=1S/C20H27ClN4O2/c21-16-5-3-6-17(15-16)23-13-11-22(12-14-23)8-1-2-9-25-19(26)18-7-4-10-24(18)20(25)27/h3,5-6,15,26H,1-2,4,7-14H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	11.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense Curated by ChEMBL					Assay Description Binding affinity towards rat 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand.				J Med Chem 39: 4439-50 (1996) Article DOI: 10.1021/jm960416g BindingDB Entry DOI: 10.7270/Q2WS8SBN
					More data for this Ligand-Target Pair

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