| Reaction Details |
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 | Report a problem with these data |
| Target | D(2) dopamine receptor |
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| Ligand | BDBM50054714 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_58195 (CHEMBL670363) |
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| IC50 | 24±n/a nM |
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| Citation |  Norman, MH; Navas, F; Thompson, JB; Rigdon, GC Synthesis and evaluation of heterocyclic carboxamides as potential antipsychotic agents. J Med Chem39:4692-703 (1997) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| D(2) dopamine receptor |
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| Name: | D(2) dopamine receptor |
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| Synonyms: | DOPAMINE D2 | DRD2_MOUSE | Dopamine D2 receptor | Dopamine Receptor D2 | Drd2 |
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| Type: | Enzyme |
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| Mol. Mass.: | 50957.64 |
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| Organism: | Mus musculus (Mouse) |
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| Description: | P61168 |
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| Residue: | 444 |
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| Sequence: | MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVS
REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTA
SILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQN
ECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPL
KGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPP
SHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMS
RRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNS
AVNPIIYTTFNIEFRKAFMKILHC
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| BDBM50054714 |
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| n/a |
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| Name | BDBM50054714 |
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| Synonyms: | 3-Amino-pyridine-2-carboxylic acid [4-(4-benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-amide | CHEMBL142211 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H26N6OS |
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| Mol. Mass. | 410.536 |
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| SMILES | Nc1cccnc1C(=O)NCCCCN1CCN(CC1)c1nsc2ccccc12 |
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| Structure | 
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