| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 7 |
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| Ligand | BDBM50504212 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1813999 (CHEMBL4313573) |
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| Ki | 3.3±n/a nM |
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| Citation |  Romeo, G; Salerno, L; Pittalą, V; Candido, M; Intagliata, S; Amata, E; Salmona, M; Cagnotto, A; Rescifina, A; Floresta, G; Modica, MN [1]Benzothieno[3,2-d]pyrimidine derivatives as ligands for the serotonergic 5-HT Eur J Med Chem183:0 (2019) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 7 |
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| Name: | 5-hydroxytryptamine receptor 7 |
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| Synonyms: | 5-HT-7 | 5-HT-X | 5-HT7 | 5-HT7L | 5-HT7S | 5-HT7b | 5HT7 | 5HT7R_HUMAN | HTR7 | Serotonin receptor 7 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 53573.08 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P34969 |
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| Residue: | 479 |
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| Sequence: | MMDVNSSGRPDLYGHLRSFLLPEVGRGLPDLSPDGGADPVAGSWAPHLLSEVTASPAPTW
DAPPDNASGCGEQINYGRVEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLI
VSLALADLSVAVAVMPFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDR
YLGITRPLTYPVRQNGKCMAKMILSVWLLSASITLPPLFGWAQNVNDDKVCLISQDFGYT
IYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFPGFPRVEPDSVIALNGIVKLQKEVE
ECANLSRLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSC
IPLWVERTFLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYRNINRKLSAAGMHEALK
LAERPERPEFVLRACTRRVLLRPEKRPPVSVWVLQSPDHHNWLADKMLTTVEKKVMIHD
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| BDBM50504212 |
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| n/a |
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| Name | BDBM50504212 |
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| Synonyms: | CHEMBL4527987 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H33N3O |
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| Mol. Mass. | 391.549 |
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| SMILES | O=C1NC2C=CC=C3CCCC1(CCCCN1CCN(CC1)c1ccccc1)C23 |c:4,t:6| |
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| Structure | 
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