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Compile Data Set for Download or QSAR

Found 49 hits with Last Name = 'candido' and Initial = 'm'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))		BDBM50139355
PNG
(2-(6-Phenylpyridin-2-ylthio)-N,N-dimethylethan-ami...)
Show SMILES CN(C)CCSc1cccc(n1)-c1ccccc1
Show InChI InChI=1S/C15H18N2S/c1-17(2)11-12-18-15-10-6-9-14(16-15)13-7-4-3-5-8-13/h3-10H,11-12H2,1-2H3
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 0.600n/an/an/an/an/an/an/an/a



Universit£ di Catania

Curated by ChEMBL


Assay Description
Binding affinity to 5HT7 receptor (unknown origin) assessed as inhibitory constant

Eur J Med Chem 183: (2019)


Article DOI: 10.1016/j.ejmech.2019.111690
BindingDB Entry DOI: 10.7270/Q2T72MQ3
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))		BDBM50504202
PNG
(CHEMBL4443201)
Show SMILES O=c1[nH]c(CCCCN2CCN(CC2)c2ccccc2)nc2ccsc12
Show InChI InChI=1S/C20H24N4OS/c25-20-19-17(9-15-26-19)21-18(22-20)8-4-5-10-23-11-13-24(14-12-23)16-6-2-1-3-7-16/h1-3,6-7,9,15H,4-5,8,10-14H2,(H,21,22,25)
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 0.850n/an/an/an/an/an/an/an/a



Universit£ di Catania

Curated by ChEMBL


Assay Description
Displacement of [3H]-5-HT from human 5HT7 receptor expressed in CHO-K1 cells incubated for 40 mins in presence of serotonin by liquid scintillation c...

Eur J Med Chem 183: (2019)


Article DOI: 10.1016/j.ejmech.2019.111690
BindingDB Entry DOI: 10.7270/Q2T72MQ3
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))		BDBM50098551
PNG
((R)-3-(2-(2-(4-methylpiperidin-1-yl)ethyl)pyrrolid...)
Show SMILES CC1CCN(CC[C@H]2CCCN2S(=O)(=O)c2cccc(O)c2)CC1 |r|
Show InChI InChI=1S/C18H28N2O3S/c1-15-7-11-19(12-8-15)13-9-16-4-3-10-20(16)24(22,23)18-6-2-5-17(21)14-18/h2,5-6,14-16,21H,3-4,7-13H2,1H3/t16-/m1/s1
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 1.90n/an/an/an/an/an/an/an/a



Universit£ di Catania

Curated by ChEMBL


Assay Description
Displacement of [3H]-5-HT from human 5HT7 receptor expressed in CHO-K1 cells incubated for 40 mins in presence of serotonin by liquid scintillation c...

Eur J Med Chem 183: (2019)


Article DOI: 10.1016/j.ejmech.2019.111690
BindingDB Entry DOI: 10.7270/Q2T72MQ3
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))		BDBM50504208
PNG
(CHEMBL4590226)
Show SMILES NC(=O)c1sccc1NC(=O)CCCCN1CCN(CC1)c1ccccc1
Show InChI InChI=1S/C20H26N4O2S/c21-20(26)19-17(9-15-27-19)22-18(25)8-4-5-10-23-11-13-24(14-12-23)16-6-2-1-3-7-16/h1-3,6-7,9,15H,4-5,8,10-14H2,(H2,21,26)(H,22,25)
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 1.90n/an/an/an/an/an/an/an/a



Universit£ di Catania

Curated by ChEMBL


Assay Description
Displacement of [3H]-5-HT from human 5HT7 receptor expressed in CHO-K1 cells incubated for 40 mins in presence of serotonin by liquid scintillation c...

Eur J Med Chem 183: (2019)


Article DOI: 10.1016/j.ejmech.2019.111690
BindingDB Entry DOI: 10.7270/Q2T72MQ3
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))		BDBM50504195
PNG
(CHEMBL4561000)
Show SMILES Clc1cccc(c1)N1CCN(CCCCc2nc3ccsc3c(=O)[nH]2)CC1
Show InChI InChI=1S/C20H23ClN4OS/c21-15-4-3-5-16(14-15)25-11-9-24(10-12-25)8-2-1-6-18-22-17-7-13-27-19(17)20(26)23-18/h3-5,7,13-14H,1-2,6,8-12H2,(H,22,23,26)
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 2.10n/an/an/an/an/an/an/an/a



Universit£ di Catania

Curated by ChEMBL


Assay Description
Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in CHO-K1 cells incubated for 60 mins by liquid scintillation counting method

Eur J Med Chem 183: (2019)


Article DOI: 10.1016/j.ejmech.2019.111690
BindingDB Entry DOI: 10.7270/Q2T72MQ3
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))		BDBM21393
PNG
(7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-o...)
Show SMILES CCCN(CCC)C1CCc2cccc(O)c2C1
Show InChI InChI=1S/C16H25NO/c1-3-10-17(11-4-2)14-9-8-13-6-5-7-16(18)15(13)12-14/h5-7,14,18H,3-4,8-12H2,1-2H3
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 2.70n/an/an/an/an/an/an/an/a



Universit£ di Catania

Curated by ChEMBL


Assay Description
Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in CHO-K1 cells incubated for 60 mins by liquid scintillation counting method

Eur J Med Chem 183: (2019)


Article DOI: 10.1016/j.ejmech.2019.111690
BindingDB Entry DOI: 10.7270/Q2T72MQ3
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))		BDBM50504212
PNG
(CHEMBL4527987)
Show SMILES O=C1NC2C=CC=C3CCCC1(CCCCN1CCN(CC1)c1ccccc1)C23 |c:4,t:6|
Show InChI InChI=1S/C25H33N3O/c29-24-25(14-7-9-20-8-6-12-22(26-24)23(20)25)13-4-5-15-27-16-18-28(19-17-27)21-10-2-1-3-11-21/h1-3,6,8,10-12,22-23H,4-5,7,9,13-19H2,(H,26,29)
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 3.30n/an/an/an/an/an/an/an/a



Universit£ di Catania

Curated by ChEMBL


Assay Description
Displacement of [3H]-HT from human 5HT7 receptor expressed in CHO cells

Eur J Med Chem 183: (2019)


Article DOI: 10.1016/j.ejmech.2019.111690
BindingDB Entry DOI: 10.7270/Q2T72MQ3
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))		BDBM50504201
PNG
(CHEMBL4437217)
Show SMILES Cn1c(CCCCN2CCN(CC2)c2ccccc2)nc2c3ccccc3sc2c1=O
Show InChI InChI=1S/C25H28N4OS/c1-27-22(26-23-20-11-5-6-12-21(20)31-24(23)25(27)30)13-7-8-14-28-15-17-29(18-16-28)19-9-3-2-4-10-19/h2-6,9-12H,7-8,13-18H2,1H3
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 3.40n/an/an/an/an/an/an/an/a



Universit£ di Catania

Curated by ChEMBL


Assay Description
Displacement of [3H]-5-HT from human 5HT7 receptor expressed in CHO-K1 cells incubated for 40 mins in presence of serotonin by liquid scintillation c...

Eur J Med Chem 183: (2019)


Article DOI: 10.1016/j.ejmech.2019.111690
BindingDB Entry DOI: 10.7270/Q2T72MQ3
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))		BDBM50504209
PNG
(CHEMBL4441943)
Show SMILES Clc1cccc(c1)N1CCN(CCCCc2nc3c4ccccc4sc3c(=O)[nH]2)CC1
Show InChI InChI=1S/C24H25ClN4OS/c25-17-6-5-7-18(16-17)29-14-12-28(13-15-29)11-4-3-10-21-26-22-19-8-1-2-9-20(19)31-23(22)24(30)27-21/h1-2,5-9,16H,3-4,10-15H2,(H,26,27,30)
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 3.80n/an/an/an/an/an/an/an/a



Universit£ di Catania

Curated by ChEMBL


Assay Description
Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in CHO-K1 cells incubated for 60 mins by liquid scintillation counting method

Eur J Med Chem 183: (2019)


Article DOI: 10.1016/j.ejmech.2019.111690
BindingDB Entry DOI: 10.7270/Q2T72MQ3
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))		BDBM50504201
PNG
(CHEMBL4437217)
Show SMILES Cn1c(CCCCN2CCN(CC2)c2ccccc2)nc2c3ccccc3sc2c1=O
Show InChI InChI=1S/C25H28N4OS/c1-27-22(26-23-20-11-5-6-12-21(20)31-24(23)25(27)30)13-7-8-14-28-15-17-29(18-16-28)19-9-3-2-4-10-19/h2-6,9-12H,7-8,13-18H2,1H3
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 5.20n/an/an/an/an/an/an/an/a



Universit£ di Catania

Curated by ChEMBL


Assay Description
Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in CHO-K1 cells incubated for 60 mins by liquid scintillation counting method

Eur J Med Chem 183: (2019)


Article DOI: 10.1016/j.ejmech.2019.111690
BindingDB Entry DOI: 10.7270/Q2T72MQ3
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))		BDBM50504204
PNG
(CHEMBL4526441)
Show SMILES CN(C)CCSc1nc2ccsc2n2cccc12
Show InChI InChI=1S/C13H15N3S2/c1-15(2)7-9-17-12-11-4-3-6-16(11)13-10(14-12)5-8-18-13/h3-6,8H,7,9H2,1-2H3
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 5.60n/an/an/an/an/an/an/an/a



Universit£ di Catania

Curated by ChEMBL


Assay Description
Binding affinity to 5HT7 receptor (unknown origin) assessed as inhibitory constant

Eur J Med Chem 183: (2019)


Article DOI: 10.1016/j.ejmech.2019.111690
BindingDB Entry DOI: 10.7270/Q2T72MQ3
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))		BDBM50504194
PNG
(CHEMBL4453552)
Show SMILES COC(=O)c1sccc1NC(=O)CCCCN1CCN(CC1)c1ccccc1
Show InChI InChI=1S/C21H27N3O3S/c1-27-21(26)20-18(10-16-28-20)22-19(25)9-5-6-11-23-12-14-24(15-13-23)17-7-3-2-4-8-17/h2-4,7-8,10,16H,5-6,9,11-15H2,1H3,(H,22,25)
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 7.5n/an/an/an/an/an/an/an/a



Universit£ di Catania

Curated by ChEMBL


Assay Description
Displacement of [3H]-5-HT from human 5HT7 receptor expressed in CHO-K1 cells incubated for 40 mins in presence of serotonin by liquid scintillation c...

Eur J Med Chem 183: (2019)


Article DOI: 10.1016/j.ejmech.2019.111690
BindingDB Entry DOI: 10.7270/Q2T72MQ3
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))		BDBM50504210
PNG
(CHEMBL4586787)
Show SMILES O=c1[nH]c(SCCCN2CCN(Cc3ccccc3)CC2)nc2c3ccccc3sc12
Show InChI InChI=1S/C24H26N4OS2/c29-23-22-21(19-9-4-5-10-20(19)31-22)25-24(26-23)30-16-6-11-27-12-14-28(15-13-27)17-18-7-2-1-3-8-18/h1-5,7-10H,6,11-17H2,(H,25,26,29)
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 9.10n/an/an/an/an/an/an/an/a



Universit£ di Catania

Curated by ChEMBL


Assay Description
Displacement of [3H]-5-HT from human 5HT7 receptor expressed in CHO-K1 cells incubated for 40 mins in presence of serotonin by liquid scintillation c...

Eur J Med Chem 183: (2019)


Article DOI: 10.1016/j.ejmech.2019.111690
BindingDB Entry DOI: 10.7270/Q2T72MQ3
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))		BDBM50504209
PNG
(CHEMBL4441943)
Show SMILES Clc1cccc(c1)N1CCN(CCCCc2nc3c4ccccc4sc3c(=O)[nH]2)CC1
Show InChI InChI=1S/C24H25ClN4OS/c25-17-6-5-7-18(16-17)29-14-12-28(13-15-29)11-4-3-10-21-26-22-19-8-1-2-9-20(19)31-23(22)24(30)27-21/h1-2,5-9,16H,3-4,10-15H2,(H,26,27,30)
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 9.40n/an/an/an/an/an/an/an/a



Universit£ di Catania

Curated by ChEMBL


Assay Description
Displacement of [3H]-5-HT from human 5HT7 receptor expressed in CHO-K1 cells incubated for 40 mins in presence of serotonin by liquid scintillation c...

Eur J Med Chem 183: (2019)


Article DOI: 10.1016/j.ejmech.2019.111690
BindingDB Entry DOI: 10.7270/Q2T72MQ3
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))		BDBM50504198
PNG
(CHEMBL4580230)
Show SMILES Nn1c(CCCCN2CCN(CC2)c2ccccc2)nc2c3ccccc3sc2c1=O
Show InChI InChI=1S/C24H27N5OS/c25-29-21(26-22-19-10-4-5-11-20(19)31-23(22)24(29)30)12-6-7-13-27-14-16-28(17-15-27)18-8-2-1-3-9-18/h1-5,8-11H,6-7,12-17,25H2
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 12n/an/an/an/an/an/an/an/a



Universit£ di Catania

Curated by ChEMBL


Assay Description
Displacement of [3H]-5-HT from human 5HT7 receptor expressed in CHO-K1 cells incubated for 40 mins in presence of serotonin by liquid scintillation c...

Eur J Med Chem 183: (2019)


Article DOI: 10.1016/j.ejmech.2019.111690
BindingDB Entry DOI: 10.7270/Q2T72MQ3
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))		BDBM50504191
PNG
(CHEMBL4516999)
Show SMILES COc1ccc(Cl)cc1N1CCN(CCCCc2nc3ccsc3c(=O)[nH]2)CC1
Show InChI InChI=1S/C21H25ClN4O2S/c1-28-18-6-5-15(22)14-17(18)26-11-9-25(10-12-26)8-3-2-4-19-23-16-7-13-29-20(16)21(27)24-19/h5-7,13-14H,2-4,8-12H2,1H3,(H,23,24,27)
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 13n/an/an/an/an/an/an/an/a



Universit£ di Catania

Curated by ChEMBL


Assay Description
Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in CHO-K1 cells incubated for 60 mins by liquid scintillation counting method

Eur J Med Chem 183: (2019)


Article DOI: 10.1016/j.ejmech.2019.111690
BindingDB Entry DOI: 10.7270/Q2T72MQ3
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))		BDBM50504192
PNG
(CHEMBL4473885)
Show SMILES O=c1[nH]c(CCCCN2CCN(CC2)c2ccccc2)nc2c3ccccc3sc12
Show InChI InChI=1S/C24H26N4OS/c29-24-23-22(19-10-4-5-11-20(19)30-23)25-21(26-24)12-6-7-13-27-14-16-28(17-15-27)18-8-2-1-3-9-18/h1-5,8-11H,6-7,12-17H2,(H,25,26,29)
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 14n/an/an/an/an/an/an/an/a



Universit£ di Catania

Curated by ChEMBL


Assay Description
Displacement of [3H]-5-HT from human 5HT7 receptor expressed in CHO-K1 cells incubated for 40 mins in presence of serotonin by liquid scintillation c...

Eur J Med Chem 183: (2019)


Article DOI: 10.1016/j.ejmech.2019.111690
BindingDB Entry DOI: 10.7270/Q2T72MQ3
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))		BDBM50504189
PNG
(CHEMBL4553199)
Show SMILES O=c1[nH]c(CCCCCN2CCN(CC2)c2ccccc2)nc2c3ccccc3sc12
Show InChI InChI=1S/C25H28N4OS/c30-25-24-23(20-11-6-7-12-21(20)31-24)26-22(27-25)13-5-2-8-14-28-15-17-29(18-16-28)19-9-3-1-4-10-19/h1,3-4,6-7,9-12H,2,5,8,13-18H2,(H,26,27,30)
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 16n/an/an/an/an/an/an/an/a



Universit£ di Catania

Curated by ChEMBL


Assay Description
Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in CHO-K1 cells incubated for 60 mins by liquid scintillation counting method

Eur J Med Chem 183: (2019)


Article DOI: 10.1016/j.ejmech.2019.111690
BindingDB Entry DOI: 10.7270/Q2T72MQ3
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))		BDBM50504189
PNG
(CHEMBL4553199)
Show SMILES O=c1[nH]c(CCCCCN2CCN(CC2)c2ccccc2)nc2c3ccccc3sc12
Show InChI InChI=1S/C25H28N4OS/c30-25-24-23(20-11-6-7-12-21(20)31-24)26-22(27-25)13-5-2-8-14-28-15-17-29(18-16-28)19-9-3-1-4-10-19/h1,3-4,6-7,9-12H,2,5,8,13-18H2,(H,26,27,30)
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 19n/an/an/an/an/an/an/an/a



Universit£ di Catania

Curated by ChEMBL


Assay Description
Displacement of [3H]-5-HT from human 5HT7 receptor expressed in CHO-K1 cells incubated for 40 mins in presence of serotonin by liquid scintillation c...

Eur J Med Chem 183: (2019)


Article DOI: 10.1016/j.ejmech.2019.111690
BindingDB Entry DOI: 10.7270/Q2T72MQ3
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))		BDBM50504194
PNG
(CHEMBL4453552)
Show SMILES COC(=O)c1sccc1NC(=O)CCCCN1CCN(CC1)c1ccccc1
Show InChI InChI=1S/C21H27N3O3S/c1-27-21(26)20-18(10-16-28-20)22-19(25)9-5-6-11-23-12-14-24(15-13-23)17-7-3-2-4-8-17/h2-4,7-8,10,16H,5-6,9,11-15H2,1H3,(H,22,25)
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 21n/an/an/an/an/an/an/an/a



Universit£ di Catania

Curated by ChEMBL


Assay Description
Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in CHO-K1 cells incubated for 60 mins by liquid scintillation counting method

Eur J Med Chem 183: (2019)


Article DOI: 10.1016/j.ejmech.2019.111690
BindingDB Entry DOI: 10.7270/Q2T72MQ3
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))		BDBM50504188
PNG
(CHEMBL4475894)
Show SMILES O=c1[nH]c(SCCCN2CCN(CC2)c2ccccc2)nc2c3ccccc3sc12
Show InChI InChI=1S/C23H24N4OS2/c28-22-21-20(18-9-4-5-10-19(18)30-21)24-23(25-22)29-16-6-11-26-12-14-27(15-13-26)17-7-2-1-3-8-17/h1-5,7-10H,6,11-16H2,(H,24,25,28)
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 23n/an/an/an/an/an/an/an/a



Universit£ di Catania

Curated by ChEMBL


Assay Description
Displacement of [3H]-5-HT from human 5HT7 receptor expressed in CHO-K1 cells incubated for 40 mins in presence of serotonin by liquid scintillation c...

Eur J Med Chem 183: (2019)


Article DOI: 10.1016/j.ejmech.2019.111690
BindingDB Entry DOI: 10.7270/Q2T72MQ3
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))		BDBM50504195
PNG
(CHEMBL4561000)
Show SMILES Clc1cccc(c1)N1CCN(CCCCc2nc3ccsc3c(=O)[nH]2)CC1
Show InChI InChI=1S/C20H23ClN4OS/c21-15-4-3-5-16(14-15)25-11-9-24(10-12-25)8-2-1-6-18-22-17-7-13-27-19(17)20(26)23-18/h3-5,7,13-14H,1-2,6,8-12H2,(H,22,23,26)
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 28n/an/an/an/an/an/an/an/a



Universit£ di Catania

Curated by ChEMBL


Assay Description
Displacement of [3H]-5-HT from human 5HT7 receptor expressed in CHO-K1 cells incubated for 40 mins in presence of serotonin by liquid scintillation c...

Eur J Med Chem 183: (2019)


Article DOI: 10.1016/j.ejmech.2019.111690
BindingDB Entry DOI: 10.7270/Q2T72MQ3
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))		BDBM50504208
PNG
(CHEMBL4590226)
Show SMILES NC(=O)c1sccc1NC(=O)CCCCN1CCN(CC1)c1ccccc1
Show InChI InChI=1S/C20H26N4O2S/c21-20(26)19-17(9-15-27-19)22-18(25)8-4-5-10-23-11-13-24(14-12-23)16-6-2-1-3-7-16/h1-3,6-7,9,15H,4-5,8,10-14H2,(H2,21,26)(H,22,25)
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 39n/an/an/an/an/an/an/an/a



Universit£ di Catania

Curated by ChEMBL


Assay Description
Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in CHO-K1 cells incubated for 60 mins by liquid scintillation counting method

Eur J Med Chem 183: (2019)


Article DOI: 10.1016/j.ejmech.2019.111690
BindingDB Entry DOI: 10.7270/Q2T72MQ3
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))		BDBM50504202
PNG
(CHEMBL4443201)
Show SMILES O=c1[nH]c(CCCCN2CCN(CC2)c2ccccc2)nc2ccsc12
Show InChI InChI=1S/C20H24N4OS/c25-20-19-17(9-15-26-19)21-18(22-20)8-4-5-10-23-11-13-24(14-12-23)16-6-2-1-3-7-16/h1-3,6-7,9,15H,4-5,8,10-14H2,(H,21,22,25)
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 40n/an/an/an/an/an/an/an/a



Universit£ di Catania

Curated by ChEMBL


Assay Description
Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in CHO-K1 cells incubated for 60 mins by liquid scintillation counting method

Eur J Med Chem 183: (2019)


Article DOI: 10.1016/j.ejmech.2019.111690
BindingDB Entry DOI: 10.7270/Q2T72MQ3
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))		BDBM50504190
PNG
(CHEMBL4473636)
Show SMILES O=c1[nH]c(CCCCN2CCN(CC2)c2ccccc2)nc2cc(sc12)-c1ccccc1
Show InChI InChI=1S/C26H28N4OS/c31-26-25-22(19-23(32-25)20-9-3-1-4-10-20)27-24(28-26)13-7-8-14-29-15-17-30(18-16-29)21-11-5-2-6-12-21/h1-6,9-12,19H,7-8,13-18H2,(H,27,28,31)
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 40n/an/an/an/an/an/an/an/a



Universit£ di Catania

Curated by ChEMBL


Assay Description
Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in CHO-K1 cells incubated for 60 mins by liquid scintillation counting method

Eur J Med Chem 183: (2019)


Article DOI: 10.1016/j.ejmech.2019.111690
BindingDB Entry DOI: 10.7270/Q2T72MQ3
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))		BDBM50504197
PNG
(CHEMBL4437211)
Show SMILES O=c1[nH]c(SCCCN2CCC(Cc3ccccc3)CC2)nc2c3ccccc3sc12
Show InChI InChI=1S/C25H27N3OS2/c29-24-23-22(20-9-4-5-10-21(20)31-23)26-25(27-24)30-16-6-13-28-14-11-19(12-15-28)17-18-7-2-1-3-8-18/h1-5,7-10,19H,6,11-17H2,(H,26,27,29)
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 40n/an/an/an/an/an/an/an/a



Universit£ di Catania

Curated by ChEMBL


Assay Description
Displacement of [3H]-5-HT from human 5HT7 receptor expressed in CHO-K1 cells incubated for 40 mins in presence of serotonin by liquid scintillation c...

Eur J Med Chem 183: (2019)


Article DOI: 10.1016/j.ejmech.2019.111690
BindingDB Entry DOI: 10.7270/Q2T72MQ3
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))		BDBM50504191
PNG
(CHEMBL4516999)
Show SMILES COc1ccc(Cl)cc1N1CCN(CCCCc2nc3ccsc3c(=O)[nH]2)CC1
Show InChI InChI=1S/C21H25ClN4O2S/c1-28-18-6-5-15(22)14-17(18)26-11-9-25(10-12-26)8-3-2-4-19-23-16-7-13-29-20(16)21(27)24-19/h5-7,13-14H,2-4,8-12H2,1H3,(H,23,24,27)
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 44n/an/an/an/an/an/an/an/a



Universit£ di Catania

Curated by ChEMBL


Assay Description
Displacement of [3H]-5-HT from human 5HT7 receptor expressed in CHO-K1 cells incubated for 40 mins in presence of serotonin by liquid scintillation c...

Eur J Med Chem 183: (2019)


Article DOI: 10.1016/j.ejmech.2019.111690
BindingDB Entry DOI: 10.7270/Q2T72MQ3
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))		BDBM50504211
PNG
(CHEMBL4466596)
Show SMILES O=c1[nH]c(CCCCN2CCN(Cc3ccccc3)CC2)nc2c3ccccc3sc12
Show InChI InChI=1S/C25H28N4OS/c30-25-24-23(20-10-4-5-11-21(20)31-24)26-22(27-25)12-6-7-13-28-14-16-29(17-15-28)18-19-8-2-1-3-9-19/h1-5,8-11H,6-7,12-18H2,(H,26,27,30)
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 56n/an/an/an/an/an/an/an/a



Universit£ di Catania

Curated by ChEMBL


Assay Description
Displacement of [3H]-5-HT from human 5HT7 receptor expressed in CHO-K1 cells incubated for 40 mins in presence of serotonin by liquid scintillation c...

Eur J Med Chem 183: (2019)


Article DOI: 10.1016/j.ejmech.2019.111690
BindingDB Entry DOI: 10.7270/Q2T72MQ3
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))		BDBM50504205
PNG
(CHEMBL4483687)
Show SMILES O=c1[nH]c(CCCCN2CCC(Cc3ccccc3)CC2)nc2c3ccccc3sc12
Show InChI InChI=1S/C26H29N3OS/c30-26-25-24(21-10-4-5-11-22(21)31-25)27-23(28-26)12-6-7-15-29-16-13-20(14-17-29)18-19-8-2-1-3-9-19/h1-5,8-11,20H,6-7,12-18H2,(H,27,28,30)
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 65n/an/an/an/an/an/an/an/a



Universit£ di Catania

Curated by ChEMBL


Assay Description
Displacement of [3H]-5-HT from human 5HT7 receptor expressed in CHO-K1 cells incubated for 40 mins in presence of serotonin by liquid scintillation c...

Eur J Med Chem 183: (2019)


Article DOI: 10.1016/j.ejmech.2019.111690
BindingDB Entry DOI: 10.7270/Q2T72MQ3
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))		BDBM50504203
PNG
(CHEMBL4555702)
Show SMILES O=c1[nH]c(CCCCN2CCC(Cc3ccccc3)CC2)nc2ccsc12
Show InChI InChI=1S/C22H27N3OS/c26-22-21-19(11-15-27-21)23-20(24-22)8-4-5-12-25-13-9-18(10-14-25)16-17-6-2-1-3-7-17/h1-3,6-7,11,15,18H,4-5,8-10,12-14,16H2,(H,23,24,26)
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 76n/an/an/an/an/an/an/an/a



Universit£ di Catania

Curated by ChEMBL


Assay Description
Displacement of [3H]-5-HT from human 5HT7 receptor expressed in CHO-K1 cells incubated for 40 mins in presence of serotonin by liquid scintillation c...

Eur J Med Chem 183: (2019)


Article DOI: 10.1016/j.ejmech.2019.111690
BindingDB Entry DOI: 10.7270/Q2T72MQ3
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))		BDBM50504203
PNG
(CHEMBL4555702)
Show SMILES O=c1[nH]c(CCCCN2CCC(Cc3ccccc3)CC2)nc2ccsc12
Show InChI InChI=1S/C22H27N3OS/c26-22-21-19(11-15-27-21)23-20(24-22)8-4-5-12-25-13-9-18(10-14-25)16-17-6-2-1-3-7-17/h1-3,6-7,11,15,18H,4-5,8-10,12-14,16H2,(H,23,24,26)
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 102n/an/an/an/an/an/an/an/a



Universit£ di Catania

Curated by ChEMBL


Assay Description
Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in CHO-K1 cells incubated for 60 mins by liquid scintillation counting method

Eur J Med Chem 183: (2019)


Article DOI: 10.1016/j.ejmech.2019.111690
BindingDB Entry DOI: 10.7270/Q2T72MQ3
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))		BDBM50504190
PNG
(CHEMBL4473636)
Show SMILES O=c1[nH]c(CCCCN2CCN(CC2)c2ccccc2)nc2cc(sc12)-c1ccccc1
Show InChI InChI=1S/C26H28N4OS/c31-26-25-22(19-23(32-25)20-9-3-1-4-10-20)27-24(28-26)13-7-8-14-29-15-17-30(18-16-29)21-11-5-2-6-12-21/h1-6,9-12,19H,7-8,13-18H2,(H,27,28,31)
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 106n/an/an/an/an/an/an/an/a



Universit£ di Catania

Curated by ChEMBL


Assay Description
Displacement of [3H]-5-HT from human 5HT7 receptor expressed in CHO-K1 cells incubated for 40 mins in presence of serotonin by liquid scintillation c...

Eur J Med Chem 183: (2019)


Article DOI: 10.1016/j.ejmech.2019.111690
BindingDB Entry DOI: 10.7270/Q2T72MQ3
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))		BDBM50504196
PNG
(CHEMBL4513482)
Show SMILES O=c1[nH]c(CCCCN2CCN(Cc3ccccc3)CC2)nc2ccsc12
Show InChI InChI=1S/C21H26N4OS/c26-21-20-18(9-15-27-20)22-19(23-21)8-4-5-10-24-11-13-25(14-12-24)16-17-6-2-1-3-7-17/h1-3,6-7,9,15H,4-5,8,10-14,16H2,(H,22,23,26)
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 133n/an/an/an/an/an/an/an/a



Universit£ di Catania

Curated by ChEMBL


Assay Description
Displacement of [3H]-5-HT from human 5HT7 receptor expressed in CHO-K1 cells incubated for 40 mins in presence of serotonin by liquid scintillation c...

Eur J Med Chem 183: (2019)


Article DOI: 10.1016/j.ejmech.2019.111690
BindingDB Entry DOI: 10.7270/Q2T72MQ3
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))		BDBM50504198
PNG
(CHEMBL4580230)
Show SMILES Nn1c(CCCCN2CCN(CC2)c2ccccc2)nc2c3ccccc3sc2c1=O
Show InChI InChI=1S/C24H27N5OS/c25-29-21(26-22-19-10-4-5-11-20(19)31-23(22)24(29)30)12-6-7-13-27-14-16-28(17-15-27)18-8-2-1-3-9-18/h1-5,8-11H,6-7,12-17,25H2
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 134n/an/an/an/an/an/an/an/a



Universit£ di Catania

Curated by ChEMBL


Assay Description
Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in CHO-K1 cells incubated for 60 mins by liquid scintillation counting method

Eur J Med Chem 183: (2019)


Article DOI: 10.1016/j.ejmech.2019.111690
BindingDB Entry DOI: 10.7270/Q2T72MQ3
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))		BDBM50504205
PNG
(CHEMBL4483687)
Show SMILES O=c1[nH]c(CCCCN2CCC(Cc3ccccc3)CC2)nc2c3ccccc3sc12
Show InChI InChI=1S/C26H29N3OS/c30-26-25-24(21-10-4-5-11-22(21)31-25)27-23(28-26)12-6-7-15-29-16-13-20(14-17-29)18-19-8-2-1-3-9-19/h1-5,8-11,20H,6-7,12-18H2,(H,27,28,30)
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 328n/an/an/an/an/an/an/an/a



Universit£ di Catania

Curated by ChEMBL


Assay Description
Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in CHO-K1 cells incubated for 60 mins by liquid scintillation counting method

Eur J Med Chem 183: (2019)


Article DOI: 10.1016/j.ejmech.2019.111690
BindingDB Entry DOI: 10.7270/Q2T72MQ3
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))		BDBM50504200
PNG
(CHEMBL4469984)
Show SMILES O=c1[nH]c(CCCCCN2CCC(Cc3ccccc3)CC2)nc2c3ccccc3sc12
Show InChI InChI=1S/C27H31N3OS/c31-27-26-25(22-11-6-7-12-23(22)32-26)28-24(29-27)13-5-2-8-16-30-17-14-21(15-18-30)19-20-9-3-1-4-10-20/h1,3-4,6-7,9-12,21H,2,5,8,13-19H2,(H,28,29,31)
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 366n/an/an/an/an/an/an/an/a



Universit£ di Catania

Curated by ChEMBL


Assay Description
Displacement of [3H]-5-HT from human 5HT7 receptor expressed in CHO-K1 cells incubated for 40 mins in presence of serotonin by liquid scintillation c...

Eur J Med Chem 183: (2019)


Article DOI: 10.1016/j.ejmech.2019.111690
BindingDB Entry DOI: 10.7270/Q2T72MQ3
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))		BDBM50504188
PNG
(CHEMBL4475894)
Show SMILES O=c1[nH]c(SCCCN2CCN(CC2)c2ccccc2)nc2c3ccccc3sc12
Show InChI InChI=1S/C23H24N4OS2/c28-22-21-20(18-9-4-5-10-19(18)30-21)24-23(25-22)29-16-6-11-26-12-14-27(15-13-26)17-7-2-1-3-8-17/h1-5,7-10H,6,11-16H2,(H,24,25,28)
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 369n/an/an/an/an/an/an/an/a



Universit£ di Catania

Curated by ChEMBL


Assay Description
Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in CHO-K1 cells incubated for 60 mins by liquid scintillation counting method

Eur J Med Chem 183: (2019)


Article DOI: 10.1016/j.ejmech.2019.111690
BindingDB Entry DOI: 10.7270/Q2T72MQ3
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))		BDBM50504199
PNG
(CHEMBL4446978)
Show SMILES O=c1[nH]c(CCCCCN2CCN(Cc3ccccc3)CC2)nc2c3ccccc3sc12
Show InChI InChI=1S/C26H30N4OS/c31-26-25-24(21-11-6-7-12-22(21)32-25)27-23(28-26)13-5-2-8-14-29-15-17-30(18-16-29)19-20-9-3-1-4-10-20/h1,3-4,6-7,9-12H,2,5,8,13-19H2,(H,27,28,31)
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 401n/an/an/an/an/an/an/an/a



Universit£ di Catania

Curated by ChEMBL


Assay Description
Displacement of [3H]-5-HT from human 5HT7 receptor expressed in CHO-K1 cells incubated for 40 mins in presence of serotonin by liquid scintillation c...

Eur J Med Chem 183: (2019)


Article DOI: 10.1016/j.ejmech.2019.111690
BindingDB Entry DOI: 10.7270/Q2T72MQ3
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))		BDBM50504196
PNG
(CHEMBL4513482)
Show SMILES O=c1[nH]c(CCCCN2CCN(Cc3ccccc3)CC2)nc2ccsc12
Show InChI InChI=1S/C21H26N4OS/c26-21-20-18(9-15-27-20)22-19(23-21)8-4-5-10-24-11-13-25(14-12-24)16-17-6-2-1-3-7-17/h1-3,6-7,9,15H,4-5,8,10-14,16H2,(H,22,23,26)
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 489n/an/an/an/an/an/an/an/a



Universit£ di Catania

Curated by ChEMBL


Assay Description
Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in CHO-K1 cells incubated for 60 mins by liquid scintillation counting method

Eur J Med Chem 183: (2019)


Article DOI: 10.1016/j.ejmech.2019.111690
BindingDB Entry DOI: 10.7270/Q2T72MQ3
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))		BDBM50504199
PNG
(CHEMBL4446978)
Show SMILES O=c1[nH]c(CCCCCN2CCN(Cc3ccccc3)CC2)nc2c3ccccc3sc12
Show InChI InChI=1S/C26H30N4OS/c31-26-25-24(21-11-6-7-12-22(21)32-25)27-23(28-26)13-5-2-8-14-29-15-17-30(18-16-29)19-20-9-3-1-4-10-20/h1,3-4,6-7,9-12H,2,5,8,13-19H2,(H,27,28,31)
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 808n/an/an/an/an/an/an/an/a



Universit£ di Catania

Curated by ChEMBL


Assay Description
Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in CHO-K1 cells incubated for 60 mins by liquid scintillation counting method

Eur J Med Chem 183: (2019)


Article DOI: 10.1016/j.ejmech.2019.111690
BindingDB Entry DOI: 10.7270/Q2T72MQ3
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))		BDBM50504200
PNG
(CHEMBL4469984)
Show SMILES O=c1[nH]c(CCCCCN2CCC(Cc3ccccc3)CC2)nc2c3ccccc3sc12
Show InChI InChI=1S/C27H31N3OS/c31-27-26-25(22-11-6-7-12-23(22)32-26)28-24(29-27)13-5-2-8-16-30-17-14-21(15-18-30)19-20-9-3-1-4-10-20/h1,3-4,6-7,9-12,21H,2,5,8,13-19H2,(H,28,29,31)
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 856n/an/an/an/an/an/an/an/a



Universit£ di Catania

Curated by ChEMBL


Assay Description
Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in CHO-K1 cells incubated for 60 mins by liquid scintillation counting method

Eur J Med Chem 183: (2019)


Article DOI: 10.1016/j.ejmech.2019.111690
BindingDB Entry DOI: 10.7270/Q2T72MQ3
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))		BDBM50504211
PNG
(CHEMBL4466596)
Show SMILES O=c1[nH]c(CCCCN2CCN(Cc3ccccc3)CC2)nc2c3ccccc3sc12
Show InChI InChI=1S/C25H28N4OS/c30-25-24-23(20-10-4-5-11-21(20)31-24)26-22(27-25)12-6-7-13-28-14-16-29(17-15-28)18-19-8-2-1-3-9-19/h1-5,8-11H,6-7,12-18H2,(H,26,27,30)
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 964n/an/an/an/an/an/an/an/a



Universit£ di Catania

Curated by ChEMBL


Assay Description
Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in CHO-K1 cells incubated for 60 mins by liquid scintillation counting method

Eur J Med Chem 183: (2019)


Article DOI: 10.1016/j.ejmech.2019.111690
BindingDB Entry DOI: 10.7270/Q2T72MQ3
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))		BDBM50504197
PNG
(CHEMBL4437211)
Show SMILES O=c1[nH]c(SCCCN2CCC(Cc3ccccc3)CC2)nc2c3ccccc3sc12
Show InChI InChI=1S/C25H27N3OS2/c29-24-23-22(20-9-4-5-10-21(20)31-23)26-25(27-24)30-16-6-13-28-14-11-19(12-15-28)17-18-7-2-1-3-8-18/h1-5,7-10,19H,6,11-17H2,(H,26,27,29)
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 993n/an/an/an/an/an/an/an/a



Universit£ di Catania

Curated by ChEMBL


Assay Description
Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in CHO-K1 cells incubated for 60 mins by liquid scintillation counting method

Eur J Med Chem 183: (2019)


Article DOI: 10.1016/j.ejmech.2019.111690
BindingDB Entry DOI: 10.7270/Q2T72MQ3
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))		BDBM50504192
PNG
(CHEMBL4473885)
Show SMILES O=c1[nH]c(CCCCN2CCN(CC2)c2ccccc2)nc2c3ccccc3sc12
Show InChI InChI=1S/C24H26N4OS/c29-24-23-22(19-10-4-5-11-20(19)30-23)25-21(26-24)12-6-7-13-27-14-16-28(17-15-27)18-8-2-1-3-9-18/h1-5,8-11H,6-7,12-17H2,(H,25,26,29)
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 1.15E+3n/an/an/an/an/an/an/an/a



Universit£ di Catania

Curated by ChEMBL


Assay Description
Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in CHO-K1 cells incubated for 60 mins by liquid scintillation counting method

Eur J Med Chem 183: (2019)


Article DOI: 10.1016/j.ejmech.2019.111690
BindingDB Entry DOI: 10.7270/Q2T72MQ3
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))		BDBM50504210
PNG
(CHEMBL4586787)
Show SMILES O=c1[nH]c(SCCCN2CCN(Cc3ccccc3)CC2)nc2c3ccccc3sc12
Show InChI InChI=1S/C24H26N4OS2/c29-23-22-21(19-9-4-5-10-20(19)31-22)25-24(26-23)30-16-6-11-27-12-14-28(15-13-27)17-18-7-2-1-3-8-18/h1-5,7-10H,6,11-17H2,(H,25,26,29)
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 2.31E+3n/an/an/an/an/an/an/an/a



Universit£ di Catania

Curated by ChEMBL


Assay Description
Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in CHO-K1 cells incubated for 60 mins by liquid scintillation counting method

Eur J Med Chem 183: (2019)


Article DOI: 10.1016/j.ejmech.2019.111690
BindingDB Entry DOI: 10.7270/Q2T72MQ3
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))		BDBM50504193
PNG
(CHEMBL4442794)
Show SMILES CN(C)CCSc1nc2c3ccccc3sc2c(=O)[nH]1
Show InChI InChI=1S/C14H15N3OS2/c1-17(2)7-8-19-14-15-11-9-5-3-4-6-10(9)20-12(11)13(18)16-14/h3-6H,7-8H2,1-2H3,(H,15,16,18)
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>1.00E+4n/an/an/an/an/an/an/an/a



Universit£ di Catania

Curated by ChEMBL


Assay Description
Displacement of [3H]-5-HT from human 5HT7 receptor expressed in CHO-K1 cells incubated for 40 mins in presence of serotonin by liquid scintillation c...

Eur J Med Chem 183: (2019)


Article DOI: 10.1016/j.ejmech.2019.111690
BindingDB Entry DOI: 10.7270/Q2T72MQ3
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))		BDBM50504213
PNG
(CHEMBL4467350)
Show SMILES O=c1[nH]c(SCCN2CCCCC2)nc2c3ccccc3sc12
Show InChI InChI=1S/C17H19N3OS2/c21-16-15-14(12-6-2-3-7-13(12)23-15)18-17(19-16)22-11-10-20-8-4-1-5-9-20/h2-3,6-7H,1,4-5,8-11H2,(H,18,19,21)
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>1.00E+4n/an/an/an/an/an/an/an/a



Universit£ di Catania

Curated by ChEMBL


Assay Description
Displacement of [3H]-5-HT from human 5HT7 receptor expressed in CHO-K1 cells incubated for 40 mins in presence of serotonin by liquid scintillation c...

Eur J Med Chem 183: (2019)


Article DOI: 10.1016/j.ejmech.2019.111690
BindingDB Entry DOI: 10.7270/Q2T72MQ3
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))		BDBM50504207
PNG
(CHEMBL4562880)
Show SMILES NCCSc1nc2c3ccccc3sc2c(=O)[nH]1
Show InChI InChI=1S/C12H11N3OS2/c13-5-6-17-12-14-9-7-3-1-2-4-8(7)18-10(9)11(16)15-12/h1-4H,5-6,13H2,(H,14,15,16)
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>1.00E+4n/an/an/an/an/an/an/an/a



Universit£ di Catania

Curated by ChEMBL


Assay Description
Displacement of [3H]-5-HT from human 5HT7 receptor expressed in CHO-K1 cells incubated for 40 mins in presence of serotonin by liquid scintillation c...

Eur J Med Chem 183: (2019)


Article DOI: 10.1016/j.ejmech.2019.111690
BindingDB Entry DOI: 10.7270/Q2T72MQ3
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))		BDBM50504206
PNG
(CHEMBL4471894)
Show SMILES O=c1[nH]c(SCCN2CCCC2)nc2c3ccccc3sc12
Show InChI InChI=1S/C16H17N3OS2/c20-15-14-13(11-5-1-2-6-12(11)22-14)17-16(18-15)21-10-9-19-7-3-4-8-19/h1-2,5-6H,3-4,7-10H2,(H,17,18,20)
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>1.00E+4n/an/an/an/an/an/an/an/a



Universit£ di Catania

Curated by ChEMBL


Assay Description
Displacement of [3H]-5-HT from human 5HT7 receptor expressed in CHO-K1 cells incubated for 40 mins in presence of serotonin by liquid scintillation c...

Eur J Med Chem 183: (2019)


Article DOI: 10.1016/j.ejmech.2019.111690
BindingDB Entry DOI: 10.7270/Q2T72MQ3
More data for this
Ligand-Target Pair