| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Carbonic anhydrase 5B, mitochondrial |
|---|
| Ligand | BDBM50504950 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1816915 (CHEMBL4316489) |
|---|
| Kd | 0.050000±n/a nM |
|---|
| Citation |  Zak?auskas, A; ?apkauskait?, E; Jezep?ikas, L; Linkuvien?, V; Paketuryt?, V; Smirnov, A; Leitans, J; Kazaks, A; Dvinskis, E; Manakova, E; Gra?ulis, S; Tars, K; Matulis, D Halogenated and di-substituted benzenesulfonamides as selective inhibitors of carbonic anhydrase isoforms. Eur J Med Chem185:0 (2020) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Carbonic anhydrase 5B, mitochondrial |
|---|
| Name: | Carbonic anhydrase 5B, mitochondrial |
|---|
| Synonyms: | CA-VB | CA5B | CAH5B_HUMAN | Carbonate dehydratase VB | Carbonic Anhydrase VB | Carbonic anhydrase 5B (CA VB) | Carbonic anhydrase 5B, mitochondrial | Carbonic anhydrase 5B, mitochondrial precursor | Carbonic anhydrase V | Carbonic anhydrase VB (CA VB) |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 36440.83 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Human (cloned) isozyme |
|---|
| Residue: | 317 |
|---|
| Sequence: | MVVMNSLRVILQASPGKLLWRKFQIPRFMPARPCSLYTCTYKTRNRALHPLWESVDLVPG
GDRQSPINIRWRDSVYDPGLKPLTISYDPATCLHVWNNGYSFLVEFEDSTDKSVIKGGPL
EHNYRLKQFHFHWGAIDAWGSEHTVDSKCFPAELHLVHWNAVRFENFEDAALEENGLAVI
GVFLKLGKHHKELQKLVDTLPSIKHKDALVEFGSFDPSCLMPTCPDYWTYSGSLTTPPLS
ESVTWIIKKQPVEVDHDQLEQFRTLLFTSEGEKEKRMVDNFRPLQPLMNRTVRSSFRHDY
VLNVQAKPKPATSQATP
|
|
|
|---|
| BDBM50504950 |
|---|
| n/a |
|---|
| Name | BDBM50504950 |
|---|
| Synonyms: | CHEMBL4573963 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C20H23ClN2O5S2 |
|---|
| Mol. Mass. | 470.99 |
|---|
| SMILES | NS(=O)(=O)c1cc(C(=O)NCc2ccccc2)c(cc1Cl)S(=O)(=O)C1CCCCC1 |
|---|
| Structure | 
|
|---|
Search and Browse
