| Reaction Details |
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 | Report a problem with these data |
| Target | Carbonic anhydrase 3 |
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| Ligand | BDBM50449831 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1816900 (CHEMBL4316474) |
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| Kd | 8300±n/a nM |
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| Citation |  Zak?auskas, A; ?apkauskait?, E; Jezep?ikas, L; Linkuvien?, V; Paketuryt?, V; Smirnov, A; Leitans, J; Kazaks, A; Dvinskis, E; Manakova, E; Gra?ulis, S; Tars, K; Matulis, D Halogenated and di-substituted benzenesulfonamides as selective inhibitors of carbonic anhydrase isoforms. Eur J Med Chem185:0 (2020) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Carbonic anhydrase 3 |
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| Name: | Carbonic anhydrase 3 |
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| Synonyms: | CA-III | CA3 | CAH3_HUMAN | Carbonate dehydratase III | Carbonic Anhydrase III | Carbonic anhydrase | Carbonic anhydrase 3 (CA III) | Carbonic anhydrase III (CA III) |
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| Type: | Enzyme |
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| Mol. Mass.: | 29562.11 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Human cloned isozyme. |
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| Residue: | 260 |
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| Sequence: | MAKEWGYASHNGPDHWHELFPNAKGENQSPVELHTKDIRHDPSLQPWSVSYDGGSAKTIL
NNGKTCRVVFDDTYDRSMLRGGPLPGPYRLRQFHLHWGSSDDHGSEHTVDGVKYAAELHL
VHWNPKYNTFKEALKQRDGIAVIGIFLKIGHENGEFQIFLDALDKIKTKGKEAPFTKFDP
SCLFPACRDYWTYQGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLLSSAENEPPVPL
VSNWRPPQPINNRVVRASFK
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| BDBM50449831 |
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| n/a |
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| Name | BDBM50449831 |
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| Synonyms: | CHEMBL4172331 |
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| Type | Small organic molecule |
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| Emp. Form. | C9H10Cl2N2O4S |
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| Mol. Mass. | 313.158 |
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| SMILES | NS(=O)(=O)c1cc(C(=O)NCCO)c(Cl)cc1Cl |
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| Structure | 
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