| Reaction Details |
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 | Report a problem with these data |
| Target | D(2) dopamine receptor |
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| Ligand | BDBM50056023 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_62255 (CHEMBL675482) |
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| Ki | 4.1±n/a nM |
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| Citation |  Kuipers, W; Kruse, CG; van Wijngaarden, I; Standaar, PJ; Tulp, MT; Veldman, N; Spek, AL; IJzerman, AP 5-HT1A-versus D2-receptor selectivity of flesinoxan and analogous N4-substituted N1-arylpiperazines. J Med Chem40:300-12 (1997) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| D(2) dopamine receptor |
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| Name: | D(2) dopamine receptor |
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| Synonyms: | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2_RAT | Dopamine D2 receptor | Dopamine2-like | Drd2 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 50931.60 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | P61169 |
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| Residue: | 444 |
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| Sequence: | MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVS
REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTA
SILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQN
ECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPL
KGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPP
SHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMS
RRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNS
AVNPIIYTTFNIEFRKAFMKILHC
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| BDBM50056023 |
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| n/a |
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| Name | BDBM50056023 |
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| Synonyms: | 1-[(E)-4-(4-Fluoro-phenyl)-but-3-enyl]-4-(2-methoxy-phenyl)-piperazine | CHEMBL104805 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H25FN2O |
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| Mol. Mass. | 340.4344 |
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| SMILES | COc1ccccc1N1CCN(CC\C=C\c2ccc(F)cc2)CC1 |
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| Structure | 
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