| Reaction Details |
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 | Report a problem with these data |
| Target | Oxygen-insensitive NAD(P)H nitroreductase |
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| Ligand | BDBM50505033 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1817031 (CHEMBL4316691) |
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| IC50 | 48000±n/a nM |
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| Citation |  Nepali, K; Lee, HY; Liou, JP Nitro-Group-Containing Drugs. J Med Chem62:2851-2893 (2019) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Oxygen-insensitive NAD(P)H nitroreductase |
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| Name: | Oxygen-insensitive NAD(P)H nitroreductase |
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| Synonyms: | 1.-.-.- | 1.5.1.34 | Dihydropteridine reductase | FMN-dependent nitroreductase | NFSB_ECOLI | Oxygen-insensitive NAD(P)H nitroreductase | Synonyms=dprA | dprA | nfnB | nfsB | nfsI | ntr |
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| Type: | PROTEIN |
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| Mol. Mass.: | 23903.39 |
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| Organism: | Escherichia coli K-12 |
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| Description: | ChEMBL_102605 |
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| Residue: | 217 |
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| Sequence: | MDIISVALKRHSTKAFDASKKLTPEQAEQIKTLLQYSPSSTNSQPWHFIVASTEEGKARV
AKSAAGNYVFNERKMLDASHVVVFCAKTAMDDVWLKLVVDQEDADGRFATPEAKAANDKG
RKFFADMHRKDLHDDAEWMAKQVYLNVGNFLLGVAALGLDAVPIEGFDAAILDAEFGLKE
KGYTSLVVVPVGHHSVEDFNATLPKSRLPQNITLTEV
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| BDBM50505033 |
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| n/a |
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| Name | BDBM50505033 |
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| Synonyms: | CHEMBL4518887 |
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| Type | Small organic molecule |
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| Emp. Form. | C11H14Cl2N3O4P |
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| Mol. Mass. | 354.126 |
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| SMILES | [O-][N+](=O)c1ccc2CNP(=O)(Oc2c1)N(CCCl)CCCl |
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| Structure | 
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