| Reaction Details |
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 | Report a problem with these data |
| Target | Protein-lysine 6-oxidase |
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| Ligand | BDBM50232678 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1823506 (CHEMBL4323270) |
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| IC50 | 1995±n/a nM |
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| Citation |  Findlay, AD; Foot, JS; Buson, A; Deodhar, M; Jarnicki, AG; Hansbro, PM; Liu, G; Schilter, H; Turner, CI; Zhou, W; Jarolimek, W Identification and Optimization of Mechanism-Based Fluoroallylamine Inhibitors of Lysyl Oxidase-like 2/3. J Med Chem62:9874-9889 (2019) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Protein-lysine 6-oxidase |
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| Name: | Protein-lysine 6-oxidase |
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| Synonyms: | 1.4.3.13 | LOX | LYOX_BOVIN | Lysyl oxidase | Protein-lysine 6-oxidase | Protein-lysine 6-oxidase, long form | Protein-lysine 6-oxidase, short form |
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| Type: | PROTEIN |
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| Mol. Mass.: | 47015.72 |
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| Organism: | Bos taurus |
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| Description: | ChEMBL_118967 |
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| Residue: | 417 |
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| Sequence: | MRFAWTALLGSLQLCALVRCAPPAASHRQPPREQAAAPGAWRQKIQWENNGQVFSLLSLG
SQYQPQRRRDPGATAPGAANATAPQMRTPILLLRNNRTAAARVRTAGPSAAAAGRPRPAA
RHWFQAGYSTSGAHDAGTSRADNQTAPGEVPTLSNLRPPNRVEVDGMVGDDPYNPYKYTD
DNPYYNYYDTYERPRPGSRYRPGYGTGYFQYGLPDLVPDPYYIQASTYVQKMAMYNLRCA
AEENCLASSAYRDVRDYDHRVLLRFPQRVKNQGTSDFLPSRPRYSWEWHSCHQHYHSMDE
FSHYDLLDASTQRRVAEGHKASFCLEDTSCDYGYHRRFACTAHTQGLSPGCYDTYNADID
CQWIDITDVKPGNYILKVSVNPSYLVPESDYSNNVVRCEIRYTGHHAYASGCTISPY
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| BDBM50232678 |
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| n/a |
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| Name | BDBM50232678 |
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| Synonyms: | CHEBI:27413 | CHEMBL1618272 | US10717734, Compound BAPN | US11098045, Compound BAPN |
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| Type | Small organic molecule |
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| Emp. Form. | C3H6N2 |
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| Mol. Mass. | 70.0931 |
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| SMILES | NCCC#N |
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| Structure | 
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