Found 1446 hits with Last Name = 'foot' and Initial = 'js' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Amine oxidase [flavin-containing] B
(Homo sapiens (Human)) | BDBM50589703
(CHEMBL5196906) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| Article
PubMed
| 8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmcl.2022.128942
BindingDB Entry DOI: 10.7270/Q2639TQ8 |
More data for this
Ligand-Target Pair | |
Lysyl oxidase homolog 2
(Homo sapiens (Human)) | BDBM50505638
(CHEMBL4457578)Show SMILES Cl.CN(C)S(=O)(=O)c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2ccc(cc12)C(O)=O Show InChI InChI=1S/C22H24FN3O4S/c1-14-21(15-5-4-6-18(11-15)31(29,30)25(2)3)19-12-16(22(27)28)7-8-20(19)26(14)13-17(23)9-10-24/h4-9,11-12H,10,13,24H2,1-3H3,(H,27,28)/b17-9- | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 83 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmaxis Ltd
Curated by ChEMBL
| Assay Description
Time-dependent inhibition of recombinant human C-terminal His-tagged LOLX2 (1-774 residues) expressed in mouse myeloma cells assessed as apparent inh... |
J Med Chem 62: 9874-9889 (2019)
Article DOI: 10.1021/acs.jmedchem.9b01283
BindingDB Entry DOI: 10.7270/Q2VM4GJ2 |
More data for this
Ligand-Target Pair | |
Retina-specific copper amine oxidase
(Homo sapiens (Human)) | BDBM50589703
(CHEMBL5196906) | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 710 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmcl.2022.128942
BindingDB Entry DOI: 10.7270/Q2639TQ8 |
More data for this
Ligand-Target Pair | |
Membrane primary amine oxidase
(Homo sapiens (Human)) | BDBM50246766
(CHEMBL489079 | Mofegiline | US9302986, Mofegiline)Show InChI InChI=1S/C11H13F2N/c12-7-10(8-14)2-1-9-3-5-11(13)6-4-9/h3-7H,1-2,8,14H2/b10-7+ | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| 1.61E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmaxis Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of human SSAO/VAP1 measuring H2O2 production by Kitz and Wilson plot analysis |
Bioorg Med Chem Lett 22: 3935-40 (2012)
Article DOI: 10.1016/j.bmcl.2012.04.111
BindingDB Entry DOI: 10.7270/Q2SQ91D6 |
More data for this
Ligand-Target Pair | |
Membrane primary amine oxidase
(Homo sapiens (Human)) | BDBM50384084
(CHEMBL2029546)Show InChI InChI=1S/C17H23FN2O2/c18-14(10-11-19)12-22-16-8-6-13(7-9-16)17(21)20-15-4-2-1-3-5-15/h6-10,15H,1-5,11-12,19H2,(H,20,21)/b14-10+ | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.64E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmaxis Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of human SSAO/VAP1 measuring H2O2 production by Kitz and Wilson plot analysis |
Bioorg Med Chem Lett 22: 3935-40 (2012)
Article DOI: 10.1016/j.bmcl.2012.04.111
BindingDB Entry DOI: 10.7270/Q2SQ91D6 |
More data for this
Ligand-Target Pair | |
Amine oxidase [flavin-containing] B
(Mus musculus) | BDBM50589703
(CHEMBL5196906) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 0.400 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmcl.2022.128942
BindingDB Entry DOI: 10.7270/Q2639TQ8 |
More data for this
Ligand-Target Pair | |
Amine oxidase [flavin-containing] B
(Homo sapiens (Human)) | BDBM50246766
(CHEMBL489079 | Mofegiline | US9302986, Mofegiline)Show InChI InChI=1S/C11H13F2N/c12-7-10(8-14)2-1-9-3-5-11(13)6-4-9/h3-7H,1-2,8,14H2/b10-7+ | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmcl.2022.128942
BindingDB Entry DOI: 10.7270/Q2639TQ8 |
More data for this
Ligand-Target Pair | |
Amine oxidase [flavin-containing] B
(Homo sapiens (Human)) | BDBM50589702
(CHEMBL5186190) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmcl.2022.128942
BindingDB Entry DOI: 10.7270/Q2639TQ8 |
More data for this
Ligand-Target Pair | |
Amine oxidase [flavin-containing] B
(Homo sapiens (Human)) | BDBM50589700
(CHEMBL5204901) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmcl.2022.128942
BindingDB Entry DOI: 10.7270/Q2639TQ8 |
More data for this
Ligand-Target Pair | |
Amine oxidase [flavin-containing] B
(Homo sapiens (Human)) | BDBM50589699
(CHEMBL5197971) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmcl.2022.128942
BindingDB Entry DOI: 10.7270/Q2639TQ8 |
More data for this
Ligand-Target Pair | |
Amine oxidase [flavin-containing] B
(Homo sapiens (Human)) | BDBM50589698
(CHEMBL5199917) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmcl.2022.128942
BindingDB Entry DOI: 10.7270/Q2639TQ8 |
More data for this
Ligand-Target Pair | |
Retina-specific copper amine oxidase
(Homo sapiens (Human)) | BDBM50589695
(CHEMBL5198317) | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmcl.2022.128942
BindingDB Entry DOI: 10.7270/Q2639TQ8 |
More data for this
Ligand-Target Pair | |
Amine oxidase [flavin-containing] B
(Homo sapiens (Human)) | BDBM50589695
(CHEMBL5198317) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmcl.2022.128942
BindingDB Entry DOI: 10.7270/Q2639TQ8 |
More data for this
Ligand-Target Pair | |
Retina-specific copper amine oxidase
(Homo sapiens (Human)) | BDBM50589700
(CHEMBL5204901) | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmcl.2022.128942
BindingDB Entry DOI: 10.7270/Q2639TQ8 |
More data for this
Ligand-Target Pair | |
Amine oxidase [flavin-containing] B
(Homo sapiens (Human)) | BDBM50246766
(CHEMBL489079 | Mofegiline | US9302986, Mofegiline)Show InChI InChI=1S/C11H13F2N/c12-7-10(8-14)2-1-9-3-5-11(13)6-4-9/h3-7H,1-2,8,14H2/b10-7+ | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Patents
| US Patent
| n/a | n/a | 5 | n/a | n/a | n/a | n/a | 7.4 | 37 |
BOEHRINGER INGELHEIM INTERNATIONAL GMBH
US Patent
| Assay Description
Recombinant human MAO-B (0.06 mg/mL; Sigma Aldrich) was used as source of MAO-B enzyme activities. The assay was performed in a similar way as for hu... |
US Patent US9302986 (2016)
BindingDB Entry DOI: 10.7270/Q2ZC81QZ |
More data for this
Ligand-Target Pair | |
Membrane primary amine oxidase
(Rattus norvegicus (Rat)) | BDBM50589703
(CHEMBL5196906) | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmcl.2022.128942
BindingDB Entry DOI: 10.7270/Q2639TQ8 |
More data for this
Ligand-Target Pair | |
Lysyl oxidase homolog 2
(Homo sapiens (Human)) | BDBM50505638
(CHEMBL4457578)Show SMILES Cl.CN(C)S(=O)(=O)c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2ccc(cc12)C(O)=O Show InChI InChI=1S/C22H24FN3O4S/c1-14-21(15-5-4-6-18(11-15)31(29,30)25(2)3)19-12-16(22(27)28)7-8-20(19)26(14)13-17(23)9-10-24/h4-9,11-12H,10,13,24H2,1-3H3,(H,27,28)/b17-9- | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmaxis Ltd
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human C-terminal His-tagged LOLX2 (1-774 residues) expressed in mouse myeloma cells using putrescine as substrate preincuba... |
J Med Chem 62: 9874-9889 (2019)
Article DOI: 10.1021/acs.jmedchem.9b01283
BindingDB Entry DOI: 10.7270/Q2VM4GJ2 |
More data for this
Ligand-Target Pair | |
Lysyl oxidase homolog 2
(Homo sapiens (Human)) | BDBM50505638
(CHEMBL4457578)Show SMILES Cl.CN(C)S(=O)(=O)c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2ccc(cc12)C(O)=O Show InChI InChI=1S/C22H24FN3O4S/c1-14-21(15-5-4-6-18(11-15)31(29,30)25(2)3)19-12-16(22(27)28)7-8-20(19)26(14)13-17(23)9-10-24/h4-9,11-12H,10,13,24H2,1-3H3,(H,27,28)/b17-9- | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmaxis Ltd
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human C-terminal His-tagged LOLX2 (1-774 residues) expressed in mouse myeloma cells using putrescine as substrate preincuba... |
J Med Chem 62: 9874-9889 (2019)
Article DOI: 10.1021/acs.jmedchem.9b01283
BindingDB Entry DOI: 10.7270/Q2VM4GJ2 |
More data for this
Ligand-Target Pair | |
Lysyl oxidase homolog 2
(Homo sapiens (Human)) | BDBM50505633
(CHEMBL4448713)Show SMILES Cl.CN(C)S(=O)(=O)c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2ccc(cc12)S(C)(=O)=O Show InChI InChI=1S/C22H26FN3O4S2/c1-15-22(16-6-5-7-19(12-16)32(29,30)25(2)3)20-13-18(31(4,27)28)8-9-21(20)26(15)14-17(23)10-11-24/h5-10,12-13H,11,14,24H2,1-4H3/b17-10- | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmaxis Ltd
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human C-terminal His-tagged LOLX2 (1-774 residues) expressed in mouse myeloma cells using putrescine as substrate preincuba... |
J Med Chem 62: 9874-9889 (2019)
Article DOI: 10.1021/acs.jmedchem.9b01283
BindingDB Entry DOI: 10.7270/Q2VM4GJ2 |
More data for this
Ligand-Target Pair | |
Amine oxidase [flavin-containing] B
(Homo sapiens (Human)) | BDBM50589703
(CHEMBL5196906) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmcl.2022.128942
BindingDB Entry DOI: 10.7270/Q2639TQ8 |
More data for this
Ligand-Target Pair | |
Retina-specific copper amine oxidase
(Homo sapiens (Human)) | BDBM50589696
(CHEMBL5201033) | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmcl.2022.128942
BindingDB Entry DOI: 10.7270/Q2639TQ8 |
More data for this
Ligand-Target Pair | |
Lysyl oxidase homolog 2
(Rattus norvegicus) | BDBM50505638
(CHEMBL4457578)Show SMILES Cl.CN(C)S(=O)(=O)c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2ccc(cc12)C(O)=O Show InChI InChI=1S/C22H24FN3O4S/c1-14-21(15-5-4-6-18(11-15)31(29,30)25(2)3)19-12-16(22(27)28)7-8-20(19)26(14)13-17(23)9-10-24/h4-9,11-12H,10,13,24H2,1-3H3,(H,27,28)/b17-9- | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmaxis Ltd
Curated by ChEMBL
| Assay Description
Inhibition of recombinant rat LOLX2 using putrescine as substrate preincubated with enzyme for 30 mins followed by substrate addition and measured ev... |
J Med Chem 62: 9874-9889 (2019)
Article DOI: 10.1021/acs.jmedchem.9b01283
BindingDB Entry DOI: 10.7270/Q2VM4GJ2 |
More data for this
Ligand-Target Pair | |
Lysyl oxidase homolog 2
(Mus musculus) | BDBM50505638
(CHEMBL4457578)Show SMILES Cl.CN(C)S(=O)(=O)c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2ccc(cc12)C(O)=O Show InChI InChI=1S/C22H24FN3O4S/c1-14-21(15-5-4-6-18(11-15)31(29,30)25(2)3)19-12-16(22(27)28)7-8-20(19)26(14)13-17(23)9-10-24/h4-9,11-12H,10,13,24H2,1-3H3,(H,27,28)/b17-9- | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmaxis Ltd
Curated by ChEMBL
| Assay Description
Inhibition of recombinant mouse C-terminal His-tagged LOLX2 (26-776 residues) expressed in mouse myeloma cells using putrescine as substrate preincub... |
J Med Chem 62: 9874-9889 (2019)
Article DOI: 10.1021/acs.jmedchem.9b01283
BindingDB Entry DOI: 10.7270/Q2VM4GJ2 |
More data for this
Ligand-Target Pair | |
Amine oxidase [flavin-containing] B
(Homo sapiens (Human)) | BDBM50589696
(CHEMBL5201033) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmcl.2022.128942
BindingDB Entry DOI: 10.7270/Q2639TQ8 |
More data for this
Ligand-Target Pair | |
Lysyl oxidase homolog 2
(Homo sapiens (Human)) | BDBM50505638
(CHEMBL4457578)Show SMILES Cl.CN(C)S(=O)(=O)c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2ccc(cc12)C(O)=O Show InChI InChI=1S/C22H24FN3O4S/c1-14-21(15-5-4-6-18(11-15)31(29,30)25(2)3)19-12-16(22(27)28)7-8-20(19)26(14)13-17(23)9-10-24/h4-9,11-12H,10,13,24H2,1-3H3,(H,27,28)/b17-9- | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmaxis Ltd
Curated by ChEMBL
| Assay Description
Inhibition of LOXL2 in human IMR90 cells using putrescine as substrate preincubated with enzyme for 30 mins followed by substrate addition and measur... |
J Med Chem 62: 9874-9889 (2019)
Article DOI: 10.1021/acs.jmedchem.9b01283
BindingDB Entry DOI: 10.7270/Q2VM4GJ2 |
More data for this
Ligand-Target Pair | |
Retina-specific copper amine oxidase
(Homo sapiens (Human)) | BDBM50246766
(CHEMBL489079 | Mofegiline | US9302986, Mofegiline)Show InChI InChI=1S/C11H13F2N/c12-7-10(8-14)2-1-9-3-5-11(13)6-4-9/h3-7H,1-2,8,14H2/b10-7+ | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmcl.2022.128942
BindingDB Entry DOI: 10.7270/Q2639TQ8 |
More data for this
Ligand-Target Pair | |
Membrane primary amine oxidase
(Mus musculus) | BDBM50246766
(CHEMBL489079 | Mofegiline | US9302986, Mofegiline)Show InChI InChI=1S/C11H13F2N/c12-7-10(8-14)2-1-9-3-5-11(13)6-4-9/h3-7H,1-2,8,14H2/b10-7+ | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmaxis Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of SSAO/VAP1 in mouse adipocytes measuring H2O2 production by Resorufin/Amplex Red assay |
Bioorg Med Chem Lett 22: 3935-40 (2012)
Article DOI: 10.1016/j.bmcl.2012.04.111
BindingDB Entry DOI: 10.7270/Q2SQ91D6 |
More data for this
Ligand-Target Pair | |
Amine oxidase [flavin-containing] B
(Homo sapiens (Human)) | BDBM50384098
(CHEMBL2029537)Show InChI InChI=1S/C10H11FN2O3/c11-8(5-6-12)7-16-10-3-1-9(2-4-10)13(14)15/h1-5H,6-7,12H2/b8-5+ | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmaxis Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant MAO-B assessed as H2O2 production by Resorufin/Amplex Red assay |
Bioorg Med Chem Lett 22: 3935-40 (2012)
Article DOI: 10.1016/j.bmcl.2012.04.111
BindingDB Entry DOI: 10.7270/Q2SQ91D6 |
More data for this
Ligand-Target Pair | |
Amine oxidase [flavin-containing] B
(Homo sapiens (Human)) | BDBM50246766
(CHEMBL489079 | Mofegiline | US9302986, Mofegiline)Show InChI InChI=1S/C11H13F2N/c12-7-10(8-14)2-1-9-3-5-11(13)6-4-9/h3-7H,1-2,8,14H2/b10-7+ | PDB
UniProtKB/SwissProt
antibodypedia
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| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmaxis Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant MAO-B assessed as H2O2 production by Resorufin/Amplex Red assay |
Bioorg Med Chem Lett 22: 3935-40 (2012)
Article DOI: 10.1016/j.bmcl.2012.04.111
BindingDB Entry DOI: 10.7270/Q2SQ91D6 |
More data for this
Ligand-Target Pair | |
Membrane primary amine oxidase
(Homo sapiens (Human)) | BDBM50384084
(CHEMBL2029546)Show InChI InChI=1S/C17H23FN2O2/c18-14(10-11-19)12-22-16-8-6-13(7-9-16)17(21)20-15-4-2-1-3-5-15/h6-10,15H,1-5,11-12,19H2,(H,20,21)/b14-10+ | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmaxis Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant SSAO/VAP1 assessed as H2O2 production by Resorufin/Amplex Red assay |
Bioorg Med Chem Lett 22: 3935-40 (2012)
Article DOI: 10.1016/j.bmcl.2012.04.111
BindingDB Entry DOI: 10.7270/Q2SQ91D6 |
More data for this
Ligand-Target Pair | |
Retina-specific copper amine oxidase
(Homo sapiens (Human)) | BDBM50589702
(CHEMBL5186190) | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmcl.2022.128942
BindingDB Entry DOI: 10.7270/Q2639TQ8 |
More data for this
Ligand-Target Pair | |
Retina-specific copper amine oxidase
(Homo sapiens (Human)) | BDBM50589699
(CHEMBL5197971) | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmcl.2022.128942
BindingDB Entry DOI: 10.7270/Q2639TQ8 |
More data for this
Ligand-Target Pair | |
Lysyl oxidase homolog 2
(Homo sapiens (Human)) | BDBM50505638
(CHEMBL4457578)Show SMILES Cl.CN(C)S(=O)(=O)c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2ccc(cc12)C(O)=O Show InChI InChI=1S/C22H24FN3O4S/c1-14-21(15-5-4-6-18(11-15)31(29,30)25(2)3)19-12-16(22(27)28)7-8-20(19)26(14)13-17(23)9-10-24/h4-9,11-12H,10,13,24H2,1-3H3,(H,27,28)/b17-9- | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmaxis Ltd
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human LOXL2 assessed as inhibition of collagen cross linking compound replenishment for 5 days and measured on day 7 by UPL... |
J Med Chem 62: 9874-9889 (2019)
Article DOI: 10.1021/acs.jmedchem.9b01283
BindingDB Entry DOI: 10.7270/Q2VM4GJ2 |
More data for this
Ligand-Target Pair | |
Amine oxidase [flavin-containing] B
(Homo sapiens (Human)) | BDBM50589697
(CHEMBL5194056) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmcl.2022.128942
BindingDB Entry DOI: 10.7270/Q2639TQ8 |
More data for this
Ligand-Target Pair | |
Lysyl oxidase homolog 2
(Homo sapiens (Human)) | BDBM50505640
(CHEMBL4556859)Show SMILES Cl.CN(C)S(=O)(=O)c1ccc(Cc2cn(C\C(F)=C\CN)nn2)cc1 Show InChI InChI=1S/C15H20FN5O2S/c1-20(2)24(22,23)15-5-3-12(4-6-15)9-14-11-21(19-18-14)10-13(16)7-8-17/h3-7,11H,8-10,17H2,1-2H3/b13-7- | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmaxis Ltd
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human C-terminal His-tagged LOLX2 (1-774 residues) expressed in mouse myeloma cells using putrescine as substrate preincuba... |
J Med Chem 62: 9874-9889 (2019)
Article DOI: 10.1021/acs.jmedchem.9b01283
BindingDB Entry DOI: 10.7270/Q2VM4GJ2 |
More data for this
Ligand-Target Pair | |
Lysyl oxidase homolog 2
(Homo sapiens (Human)) | BDBM50505638
(CHEMBL4457578)Show SMILES Cl.CN(C)S(=O)(=O)c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2ccc(cc12)C(O)=O Show InChI InChI=1S/C22H24FN3O4S/c1-14-21(15-5-4-6-18(11-15)31(29,30)25(2)3)19-12-16(22(27)28)7-8-20(19)26(14)13-17(23)9-10-24/h4-9,11-12H,10,13,24H2,1-3H3,(H,27,28)/b17-9- | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmaxis Ltd
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human C-terminal His-tagged LOLX2 (1-774 residues) expressed in mouse myeloma cells assessed as inhibition of collagen oxid... |
J Med Chem 62: 9874-9889 (2019)
Article DOI: 10.1021/acs.jmedchem.9b01283
BindingDB Entry DOI: 10.7270/Q2VM4GJ2 |
More data for this
Ligand-Target Pair | |
Lysyl oxidase homolog 3
(Homo sapiens (Human)) | BDBM50505638
(CHEMBL4457578)Show SMILES Cl.CN(C)S(=O)(=O)c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2ccc(cc12)C(O)=O Show InChI InChI=1S/C22H24FN3O4S/c1-14-21(15-5-4-6-18(11-15)31(29,30)25(2)3)19-12-16(22(27)28)7-8-20(19)26(14)13-17(23)9-10-24/h4-9,11-12H,10,13,24H2,1-3H3,(H,27,28)/b17-9- | UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmaxis Ltd
Curated by ChEMBL
| Assay Description
Inhibition of recombinant C-terminal His-tagged human LOXL3 (1 to 753 residues) expressed in CHO cells using putrescine as substrate preincubated wit... |
J Med Chem 62: 9874-9889 (2019)
Article DOI: 10.1021/acs.jmedchem.9b01283
BindingDB Entry DOI: 10.7270/Q2VM4GJ2 |
More data for this
Ligand-Target Pair | |
Retina-specific copper amine oxidase
(Homo sapiens (Human)) | BDBM50589697
(CHEMBL5194056) | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmcl.2022.128942
BindingDB Entry DOI: 10.7270/Q2639TQ8 |
More data for this
Ligand-Target Pair | |
Retina-specific copper amine oxidase
(Homo sapiens (Human)) | BDBM50589703
(CHEMBL5196906) | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmcl.2022.128942
BindingDB Entry DOI: 10.7270/Q2639TQ8 |
More data for this
Ligand-Target Pair | |
Lysyl oxidase homolog 2
(Homo sapiens (Human)) | BDBM50505653
(CHEMBL4458907)Show SMILES Cl.CN(C)S(=O)(=O)c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2ccc(NS(C)(=O)=O)cc12 Show InChI InChI=1S/C22H27FN4O4S2/c1-15-22(16-6-5-7-19(12-16)33(30,31)26(2)3)20-13-18(25-32(4,28)29)8-9-21(20)27(15)14-17(23)10-11-24/h5-10,12-13,25H,11,14,24H2,1-4H3/b17-10- | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmaxis Ltd
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human C-terminal His-tagged LOLX2 (1-774 residues) expressed in mouse myeloma cells using putrescine as substrate preincuba... |
J Med Chem 62: 9874-9889 (2019)
Article DOI: 10.1021/acs.jmedchem.9b01283
BindingDB Entry DOI: 10.7270/Q2VM4GJ2 |
More data for this
Ligand-Target Pair | |
Lysyl oxidase homolog 2
(Homo sapiens (Human)) | BDBM50505658
(CHEMBL4581458)Show SMILES Cl.CN(C)S(=O)(=O)c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2cccnc12 Show InChI InChI=1S/C20H23FN4O2S/c1-14-19(15-6-4-7-17(12-15)28(26,27)24(2)3)20-18(8-5-11-23-20)25(14)13-16(21)9-10-22/h4-9,11-12H,10,13,22H2,1-3H3/b16-9- | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmaxis Ltd
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human C-terminal His-tagged LOLX2 (1-774 residues) expressed in mouse myeloma cells using putrescine as substrate preincuba... |
J Med Chem 62: 9874-9889 (2019)
Article DOI: 10.1021/acs.jmedchem.9b01283
BindingDB Entry DOI: 10.7270/Q2VM4GJ2 |
More data for this
Ligand-Target Pair | |
Lysyl oxidase homolog 2
(Homo sapiens (Human)) | BDBM50505647
(CHEMBL4531065)Show SMILES Cl.CN(C)S(=O)(=O)c1ccc(OCc2cn(C\C(F)=C\CN)nn2)c(Cl)c1 Show InChI InChI=1S/C15H19ClFN5O3S/c1-21(2)26(23,24)13-3-4-15(14(16)7-13)25-10-12-9-22(20-19-12)8-11(17)5-6-18/h3-5,7,9H,6,8,10,18H2,1-2H3/b11-5- | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmaxis Ltd
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human C-terminal His-tagged LOLX2 (1-774 residues) expressed in mouse myeloma cells using putrescine as substrate preincuba... |
J Med Chem 62: 9874-9889 (2019)
Article DOI: 10.1021/acs.jmedchem.9b01283
BindingDB Entry DOI: 10.7270/Q2VM4GJ2 |
More data for this
Ligand-Target Pair | |
Membrane primary amine oxidase
(Homo sapiens (Human)) | BDBM50246766
(CHEMBL489079 | Mofegiline | US9302986, Mofegiline)Show InChI InChI=1S/C11H13F2N/c12-7-10(8-14)2-1-9-3-5-11(13)6-4-9/h3-7H,1-2,8,14H2/b10-7+ | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
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| Article
PubMed
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmaxis Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant SSAO/VAP1 assessed as H2O2 production by Resorufin/Amplex Red assay |
Bioorg Med Chem Lett 22: 3935-40 (2012)
Article DOI: 10.1016/j.bmcl.2012.04.111
BindingDB Entry DOI: 10.7270/Q2SQ91D6 |
More data for this
Ligand-Target Pair | |
Lysyl oxidase homolog 2
(Homo sapiens (Human)) | BDBM50505657
(CHEMBL4467234)Show SMILES Cl.CN(C)S(=O)(=O)c1ccc(NCc2cn(C\C(F)=C\CN)nn2)cc1 Show InChI InChI=1S/C15H21FN6O2S/c1-21(2)25(23,24)15-5-3-13(4-6-15)18-9-14-11-22(20-19-14)10-12(16)7-8-17/h3-7,11,18H,8-10,17H2,1-2H3/b12-7- | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmaxis Ltd
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human C-terminal His-tagged LOLX2 (1-774 residues) expressed in mouse myeloma cells using putrescine as substrate preincuba... |
J Med Chem 62: 9874-9889 (2019)
Article DOI: 10.1021/acs.jmedchem.9b01283
BindingDB Entry DOI: 10.7270/Q2VM4GJ2 |
More data for this
Ligand-Target Pair | |
Membrane primary amine oxidase
(Homo sapiens (Human)) | BDBM50384083
(CHEMBL2029545)Show InChI InChI=1S/C16H21FN2O2/c17-13(9-10-18)11-21-15-7-5-12(6-8-15)16(20)19-14-3-1-2-4-14/h5-9,14H,1-4,10-11,18H2,(H,19,20)/b13-9+ | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmaxis Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant SSAO/VAP1 assessed as H2O2 production by Resorufin/Amplex Red assay |
Bioorg Med Chem Lett 22: 3935-40 (2012)
Article DOI: 10.1016/j.bmcl.2012.04.111
BindingDB Entry DOI: 10.7270/Q2SQ91D6 |
More data for this
Ligand-Target Pair | |
Membrane primary amine oxidase
(Homo sapiens (Human)) | BDBM50384095
(CHEMBL2029534)Show InChI InChI=1S/C11H14FNOS/c1-15-11-4-2-10(3-5-11)14-8-9(12)6-7-13/h2-6H,7-8,13H2,1H3/b9-6+ | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmaxis Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant SSAO/VAP1 assessed as H2O2 production by Resorufin/Amplex Red assay |
Bioorg Med Chem Lett 22: 3935-40 (2012)
Article DOI: 10.1016/j.bmcl.2012.04.111
BindingDB Entry DOI: 10.7270/Q2SQ91D6 |
More data for this
Ligand-Target Pair | |
Lysyl oxidase homolog 2
(Homo sapiens (Human)) | BDBM50505643
(CHEMBL4582216)Show SMILES Cl.CN(C)C(=O)c1ccc2n(C\C(F)=C\CN)c(C)c(-c3cccc(c3)S(=O)(=O)N(C)C)c2c1 Show InChI InChI=1S/C24H29FN4O3S/c1-16-23(17-7-6-8-20(13-17)33(31,32)28(4)5)21-14-18(24(30)27(2)3)9-10-22(21)29(16)15-19(25)11-12-26/h6-11,13-14H,12,15,26H2,1-5H3/b19-11- | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmaxis Ltd
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human C-terminal His-tagged LOLX2 (1-774 residues) expressed in mouse myeloma cells using putrescine as substrate preincuba... |
J Med Chem 62: 9874-9889 (2019)
Article DOI: 10.1021/acs.jmedchem.9b01283
BindingDB Entry DOI: 10.7270/Q2VM4GJ2 |
More data for this
Ligand-Target Pair | |
Amine oxidase [flavin-containing] B
(Homo sapiens (Human)) | BDBM50589701
(CHEMBL5186898) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 26 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmcl.2022.128942
BindingDB Entry DOI: 10.7270/Q2639TQ8 |
More data for this
Ligand-Target Pair | |
Retina-specific copper amine oxidase
(Homo sapiens (Human)) | BDBM50589703
(CHEMBL5196906) | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 29 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmcl.2022.128942
BindingDB Entry DOI: 10.7270/Q2639TQ8 |
More data for this
Ligand-Target Pair | |
Membrane primary amine oxidase
(Homo sapiens (Human)) | BDBM50384087
(CHEMBL2029549)Show SMILES C[C@@H](NC(=O)c1ccc(OC\C(F)=C/CN)cc1)c1ccccc1 |r| Show InChI InChI=1S/C19H21FN2O2/c1-14(15-5-3-2-4-6-15)22-19(23)16-7-9-18(10-8-16)24-13-17(20)11-12-21/h2-11,14H,12-13,21H2,1H3,(H,22,23)/b17-11+/t14-/m1/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmaxis Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant SSAO/VAP1 assessed as H2O2 production by Resorufin/Amplex Red assay |
Bioorg Med Chem Lett 22: 3935-40 (2012)
Article DOI: 10.1016/j.bmcl.2012.04.111
BindingDB Entry DOI: 10.7270/Q2SQ91D6 |
More data for this
Ligand-Target Pair | |
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