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TargetMu-type opioid receptor
LigandBDBM50058152
Substrate/Competitorn/a
Meas. Tech.ChEMBL_148517 (CHEMBL758127)
Ki 1.50±n/a nM
Citation Fang, XLarson, DLPortoghese, PS 7-spirobenzocyclohexyl derivatives of naltrexone, oxymorphone, and hydromorphone as selective opioid receptor ligands. J Med Chem40:3064-70 (1997) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Mu-type opioid receptor
Name:Mu-type opioid receptor
Synonyms:M-OR-1 | MOR-1 | Mor | OPIATE Mu | OPRM_MOUSE | Opioid receptors; mu and delta | Oprm | Oprm1
Type:Enzyme Catalytic Domain
Mol. Mass.:44431.62
Organism:MOUSE
Description:OPIATE Mu OPRM1 MOUSE::P42866
Residue:398
Sequence:
MDSSAGPGNISDCSDPLAPASCSPAPGSWLNLSHVDGNQSDPCGPNRTGLGGSHSLCPQT
GSPSMVTAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATST
LPFQSVNYLMGTWPFGNILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRT
PRNAKIVNVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFA
FIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYV
IIKALITIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSTIEQ
QNSARIRQNTREHPSTANTVDRTNHQLENLEAETAPLP
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  Blast E-value cutoff:
BDBM50058152
n/a
NameBDBM50058152
Synonyms:7-(2''-spiroindanyl)naltrexone | CHEMBL610293
TypeSmall organic molecule
Emp. Form.C28H29NO4
Mol. Mass.443.5342
SMILES[H][C@@]12Oc3c4c(C[C@@]5([H])N(CC6CC6)CC[C@@]14[C@@]5(O)CC1(Cc4ccccc4C1)C2=O)ccc3O |r,THB:10:9:17:6.5.4|
Structure
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