| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Cathepsin G |
|---|
| Ligand | BDBM50060330 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_45530 (CHEMBL660233) |
|---|
| pH | 7.5±n/a |
|---|
| Ki | >15000±n/a nM |
|---|
| Comments | extracted |
|---|
| Citation |  Regan, J; McGarry, D; Bruno, J; Green, D; Newman, J; Hsu, CY; Kline, J; Barton, J; Travis, J; Choi, YM; Volz, F; Pauls, H; Harrison, R; Zilberstein, A; Ben-Sasson, SA; Chang, M Anionic- and lipophilic-mediated surface binding inhibitors of human leukocyte elastase. J Med Chem40:3408-22 (1997) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Cathepsin G |
|---|
| Name: | Cathepsin G |
|---|
| Synonyms: | CATG_HUMAN | CG | CTSG |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 28860.08 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_1469016 |
|---|
| Residue: | 255 |
|---|
| Sequence: | MQPLLLLLAFLLPTGAEAGEIIGGRESRPHSRPYMAYLQIQSPAGQSRCGGFLVREDFVL
TAAHCWGSNINVTLGAHNIQRRENTQQHITARRAIRHPQYNQRTIQNDIMLLQLSRRVRR
NRNVNPVALPRAQEGLRPGTLCTVAGWGRVSMRRGTDTLREVQLRVQRDRQCLRIFGSYD
PRRQICVGDRRERKAAFKGDSGGPLLCNNVAHGIVSYGKSSGVPPEVFTRVSSFLPWIRT
TMRSFKLLDQMETPL
|
|
|
|---|
| BDBM50060330 |
|---|
| n/a |
|---|
| Name | BDBM50060330 |
|---|
| Synonyms: | CHEMBL265335 | {5-[4-(2-Carboxymethoxy-5-methoxy-benzyl)-5-methoxy-2-(3-phenyl-propoxy)-benzyl]-2-[4-{5-carboxymethoxy-2-methoxy-4-[2-methoxy-4-methyl-5-(3-phenyl-propoxy)-benzyl]-benzyl}-2-methoxy-5-(3-phenyl-propoxy)-benzyl]-4-methoxy-phenoxy}-acetic acid |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C81H86O18 |
|---|
| Mol. Mass. | 1347.5387 |
|---|
| SMILES | COc1ccc(OCC(O)=O)c(Cc2cc(OCCCc3ccccc3)c(Cc3cc(OCC(O)=O)c(Cc4cc(OCCCc5ccccc5)c(Cc5cc(OCC(O)=O)c(Cc6cc(OCCCc7ccccc7)c(C)cc6OC)cc5OC)cc4OC)cc3OC)cc2OC)c1 |
|---|
| Structure | 
|
|---|
Search and Browse
