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TargetCathepsin G
LigandBDBM50060330
Substrate/Competitorn/a
Meas. Tech.ChEMBL_45530
pH7.5±n/a
Ki>15000±n/a nM
Commentsextracted
Citation Regan JMcGarry DBruno JGreen DNewman JHsu CYKline JBarton JTravis JChoi YMVolz FPauls HHarrison RZilberstein ABen-Sasson SAChang M Anionic- and lipophilic-mediated surface binding inhibitors of human leukocyte elastase. J Med Chem 40:3408-22 (1997) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Cathepsin G
Name:Cathepsin G
Synonyms:CG
Type:PROTEIN
Mol. Mass.:28860.08
Organism:Homo sapiens (Human)
Description:ChEMBL_1469016
Residue:255
Sequence:
MQPLLLLLAFLLPTGAEAGEIIGGRESRPHSRPYMAYLQIQSPAGQSRCGGFLVREDFVL
TAAHCWGSNINVTLGAHNIQRRENTQQHITARRAIRHPQYNQRTIQNDIMLLQLSRRVRR
NRNVNPVALPRAQEGLRPGTLCTVAGWGRVSMRRGTDTLREVQLRVQRDRQCLRIFGSYD
PRRQICVGDRRERKAAFKGDSGGPLLCNNVAHGIVSYGKSSGVPPEVFTRVSSFLPWIRT
TMRSFKLLDQMETPL
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  Blast E-value cutoff:
BDBM50060330
n/a
NameBDBM50060330
Synonyms:CHEMBL265335 | {5-[4-(2-Carboxymethoxy-5-methoxy-benzyl)-5-methoxy-2-(3-phenyl-propoxy)-benzyl]-2-[4-{5-carboxymethoxy-2-methoxy-4-[2-methoxy-4-methyl-5-(3-phenyl-propoxy)-benzyl]-benzyl}-2-methoxy-5-(3-phenyl-propoxy)-benzyl]-4-methoxy-phenoxy}-acetic acid
TypeSmall organic molecule
Emp. Form.C81H86O18
Mol. Mass.1347.5387
SMILESCOc1ccc(OCC(O)=O)c(Cc2cc(OCCCc3ccccc3)c(Cc3cc(OCC(O)=O)c(Cc4cc(OCCCc5ccccc5)c(Cc5cc(OCC(O)=O)c(Cc6cc(OCCCc7ccccc7)c(C)cc6OC)cc5OC)cc4OC)cc3OC)cc2OC)c1
Structure
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