| Reaction Details |
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 | Report a problem with these data |
| Target | Tubulin beta-2B chain |
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| Ligand | BDBM50060956 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_211335 (CHEMBL820778) |
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| IC50 | 2800±n/a nM |
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| Citation |  Miller, TA; Bulman, AL; Thompson, CD; Garst, ME; Macdonald, TL Synthesis and structure-activity profiles of A-homoestranes, the estratropones. J Med Chem40:3836-41 (1997) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Tubulin beta-2B chain |
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| Name: | Tubulin beta-2B chain |
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| Synonyms: | TBB2B_BOVIN | TUBB2B | Tubulin | Tubulin beta chain |
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| Type: | PROTEIN |
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| Mol. Mass.: | 49932.38 |
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| Organism: | Bos taurus |
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| Description: | ChEMBL_211651 |
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| Residue: | 445 |
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| Sequence: | MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYV
PRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVV
RKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVV
EPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCL
RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDSKNMM
AACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRG
LKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS
EYQQYQDATADEQGEFEEEEGEDEA
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| BDBM50060956 |
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| n/a |
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| Name | BDBM50060956 |
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| Synonyms: | (1S,3aS,3bR,10bS,12aS)-8-Chloro-1-hydroxy-12a-methyl-2,3,3a,3b,4,5,10b,11,12,12a-decahydro-1H-cyclohepta[a]cyclopenta[f]naphthalen-7-one | CHEMBL339413 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H23ClO2 |
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| Mol. Mass. | 318.838 |
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| SMILES | C[C@]12CC[C@H]3[C@@H](CCc4cc(=O)c(Cl)ccc34)[C@@H]1CC[C@@H]2O |
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| Structure | 
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