| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Serine protease 1 |
|---|
| Ligand | BDBM50062019 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_210650 (CHEMBL811612) |
|---|
| Ki | 330±n/a nM |
|---|
| Citation |  Maduskuie, TP; McNamara, KJ; Ru, Y; Knabb, RM; Stouten, PF Rational design and synthesis of novel, potent bis-phenylamidine carboxylate factor Xa inhibitors. J Med Chem41:53-62 (1998) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Serine protease 1 |
|---|
| Name: | Serine protease 1 |
|---|
| Synonyms: | Alpha-trypsin chain 1 | Alpha-trypsin chain 2 | Beta-trypsin | Cationic trypsinogen | PRSS1 | Serine protease 1 | TRP1 | TRY1 | TRY1_HUMAN | TRYP1 | Thrombin & trypsin | Trypsin | Trypsin I | Trypsin-1 |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 26557.80 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P07477 |
|---|
| Residue: | 247 |
|---|
| Sequence: | MNPLLILTFVAAALAAPFDDDDKIVGGYNCEENSVPYQVSLNSGYHFCGGSLINEQWVVS
AGHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVIN
ARVSTISLPTAPPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKIT
SNMFCVGFLEGGKDSCQGDSGGPVVCNGQLQGVVSWGDGCAQKNKPGVYTKVYNYVKWIK
NTIAANS
|
|
|
|---|
| BDBM50062019 |
|---|
| n/a |
|---|
| Name | BDBM50062019 |
|---|
| Synonyms: | 4-[3-(3-Carbamimidoyl-phenyl)-4-methoxycarbonyl-butyl]-benzoic acid methyl ester | CHEMBL156043 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C21H24N2O4 |
|---|
| Mol. Mass. | 368.4263 |
|---|
| SMILES | COC(=O)CC(CCc1ccc(cc1)C(=O)OC)c1cccc(c1)C(N)=N |
|---|
| Structure | 
|
|---|
Search and Browse
