| Reaction Details |
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 | Report a problem with these data |
| Target | Mitogen-activated protein kinase 15 |
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| Ligand | BDBM50509369 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1838055 (CHEMBL4338188) |
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| IC50 | >10000±n/a nM |
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| Citation |  Hansen, KØ; Andersen, JH; Bayer, A; Pandey, SK; Lorentzen, M; Jørgensen, KB; Sydnes, MO; Guttormsen, Y; Baumann, M; Koch, U; Klebl, B; Eickhoff, J; Haug, BE; Isaksson, J; Hansen, EH Kinase Chemodiversity from the Arctic: The Breitfussins. J Med Chem62:10167-10181 (2019) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Mitogen-activated protein kinase 15 |
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| Name: | Mitogen-activated protein kinase 15 |
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| Synonyms: | ERK-8 | ERK7 | ERK8 | Extracellular signal-regulated kinase 8 | MAPK15 | MK15_HUMAN | Mitogen-activated protein kinase 15 |
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| Type: | Serine/threonine-protein kinase |
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| Mol. Mass.: | 59850.14 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_95147356 |
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| Residue: | 544 |
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| Sequence: | MCTVVDPRIVRRYLLRRQLGQGAYGIVWKAVDRRTGEVVAIKKIFDAFRDKTDAQRTFRE
ITLLQEFGDHPNIISLLDVIRAENDRDIYLVFEFMDTDLNAVIRKGGLLQDVHVRSIFYQ
LLRATRFLHSGHVVHRDQKPSNVLLDANCTVKLCDFGLARSLGDLPEGPEDQAVTEYVAT
RWYRAPEVLLSSHRYTLGVDMWSLGCILGEMLRGRPLFPGTSTLHQLELILETIPPPSEE
DLLALGSGCRASVLHQLGSRPRQTLDALLPPDTSPEALDLLRRLLVFAPDKRLSATQALQ
HPYVQRFHCPSDEWAREADVRPRAHEGVQLSVPEYRSRVYQMILECGGSSGTSREKGPEG
VSPSQAHLHKPRADPQLPSRTPVQGPRPRPQSSPGHDPAEHESPRAAKNVPRQNSAPLLQ
TALLGNGERPPGAKEAPPLTLSLVKPSGRGAAPSLTSQAAAQVANQALIRGDWNRGGGVR
VASVQQVPPRLPPEARPGRRMFSTSALQGAQGGARALLGGYSQAYGTVCHSALGHLPLLE
GHHV
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| BDBM50509369 |
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| n/a |
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| Name | BDBM50509369 |
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| Synonyms: | CHEMBL4548361 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H11BrIN3O2 |
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| Mol. Mass. | 484.086 |
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| SMILES | COc1cc(Br)cc2[nH]c(I)c(-c3cnc(o3)-c3ccc[nH]3)c12 |
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| Structure | 
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