| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Retinoic acid receptor gamma |
|---|
| Ligand | BDBM50066904 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_195993 (CHEMBL800482) |
|---|
| EC50 | 330±n/a nM |
|---|
| Citation |  Benbrook, DM; Subramanian, S; Gale, JB; Liu, S; Brown, CW; Boehm, MF; Berlin, KD Synthesis and characterization of heteroarotinoids demonstrate structure specificity relationships. J Med Chem41:3753-7 (1998) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Retinoic acid receptor gamma |
|---|
| Name: | Retinoic acid receptor gamma |
|---|
| Synonyms: | NR1B3 | Nuclear receptor subfamily 1 group B member 3 | RAR-gamma | RARG | RARG_HUMAN | Retinoic acid receptor RXR-alpha/gamma | Retinoic acid receptor gamma | Retinoid receptor |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 50345.43 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_1458016 |
|---|
| Residue: | 454 |
|---|
| Sequence: | MATNKERLFAAGALGPGSGYPGAGFPFAFPGALRGSPPFEMLSPSFRGLGQPDLPKEMAS
LSVETQSTSSEEMVPSSPSPPPPPRVYKPCFVCNDKSSGYHYGVSSCEGCKGFFRRSIQK
NMVYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKEAVRNDRNKKKKEVKEEGSPDSY
ELSPQLEELITKVSKAHQETFPSLCQLGKYTTNSSADHRVQLDLGLWDKFSELATKCIIK
IVEFAKRLPGFTGLSIADQITLLKAACLDILMLRICTRYTPEQDTMTFSDGLTLNRTQMH
NAGFGPLTDLVFAFAGQLLPLEMDDTETGLLSAICLICGDRMDLEEPEKVDKLQEPLLEA
LRLYARRRRPSQPYMFPRMLMKITDLRGISTKGAERAITLKMEIPGPMPPLIREMLENPE
MFEDDSSQPGPHPNASSEDEVPGGQGKGGLKSPA
|
|
|
|---|
| BDBM50066904 |
|---|
| n/a |
|---|
| Name | BDBM50066904 |
|---|
| Synonyms: | 4-[(E)-2-(4,4-Dimethyl-chroman-6-yl)-propenyl]-benzoic acid methyl ester | 4-[2-(4,4-Dimethyl-chroman-6-yl)-propenyl]-benzoic acid methyl ester | CHEMBL34464 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C22H24O3 |
|---|
| Mol. Mass. | 336.4242 |
|---|
| SMILES | COC(=O)c1ccc(\C=C(/C)c2ccc3OCCC(C)(C)c3c2)cc1 |
|---|
| Structure | 
|
|---|
Search and Browse
