| Reaction Details |
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 | Report a problem with these data |
| Target | Retinoic acid receptor alpha |
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| Ligand | BDBM50066904 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_197392 (CHEMBL799711) |
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| EC50 | 1100±n/a nM |
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| Citation |  Benbrook, DM; Subramanian, S; Gale, JB; Liu, S; Brown, CW; Boehm, MF; Berlin, KD Synthesis and characterization of heteroarotinoids demonstrate structure specificity relationships. J Med Chem41:3753-7 (1998) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Retinoic acid receptor alpha |
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| Name: | Retinoic acid receptor alpha |
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| Synonyms: | NR1B1 | Nuclear receptor subfamily 1 group B member 1 | RAR-alpha | RARA | RARA_HUMAN | Retinoic acid receptor alpha | Retinoic acid receptor alpha/Retinoid X receptor alpha | Retinoid X receptor gamma/retinoic acid receptor alpha | Retinoid receptor |
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| Type: | PROTEIN |
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| Mol. Mass.: | 50778.87 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1466191 |
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| Residue: | 462 |
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| Sequence: | MASNSSSCPTPGGGHLNGYPVPPYAFFFPPMLGGLSPPGALTTLQHQLPVSGYSTPSPAT
IETQSSSSEEIVPSPPSPPPLPRIYKPCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNM
VYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKESVRNDRNKKKKEVPKPECSESYTL
TPEVGELIEKVRKAHQETFPALCQLGKYTTNNSSEQRVSLDIDLWDKFSELSTKCIIKTV
EFAKQLPGFTTLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRTQMHNA
GFGPLTDLVFAFANQLLPLEMDDAETGLLSAICLICGDRQDLEQPDRVDMLQEPLLEALK
VYVRKRRPSRPHMFPKMLMKITDLRSISAKGAERVITLKMEIPGSMPPLIQEMLENSEGL
DTLSGQPGGGGRDGGGLAPPPGSCSPSLSPSSNRSSPATHSP
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| BDBM50066904 |
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| n/a |
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| Name | BDBM50066904 |
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| Synonyms: | 4-[(E)-2-(4,4-Dimethyl-chroman-6-yl)-propenyl]-benzoic acid methyl ester | 4-[2-(4,4-Dimethyl-chroman-6-yl)-propenyl]-benzoic acid methyl ester | CHEMBL34464 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H24O3 |
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| Mol. Mass. | 336.4242 |
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| SMILES | COC(=O)c1ccc(\C=C(/C)c2ccc3OCCC(C)(C)c3c2)cc1 |
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| Structure | 
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