| Reaction Details |
|---|
 | Report a problem with these data |
| Target | L-lactate dehydrogenase A chain |
|---|
| Ligand | BDBM50066975 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_96428 (CHEMBL706376) |
|---|
| Ki | 700±n/a nM |
|---|
| Citation |  Deck, LM; Royer, RE; Chamblee, BB; Hernandez, VM; Malone, RR; Torres, JE; Hunsaker, LA; Piper, RC; Makler, MT; Vander Jagt, DL Selective inhibitors of human lactate dehydrogenases and lactate dehydrogenase from the malarial parasite Plasmodium falciparum. J Med Chem41:3879-87 (1998) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| L-lactate dehydrogenase A chain |
|---|
| Name: | L-lactate dehydrogenase A chain |
|---|
| Synonyms: | Cell proliferation-inducing gene 19 protein | L-lactate dehydrogenase A | L-lactate dehydrogenase A Chain | LDH muscle subunit | LDH-A | LDH-M | LDHA | LDHA_HUMAN | Lactate dehydrogenase A (LDHA) | Renal carcinoma antigen NY-REN-59 |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 36694.85 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P00338::PDB Code: 4ajp |
|---|
| Residue: | 332 |
|---|
| Sequence: | MATLKDQLIYNLLKEEQTPQNKITVVGVGAVGMACAISILMKDLADELALVDVIEDKLKG
EMMDLQHGSLFLRTPKIVSGKDYNVTANSKLVIITAGARQQEGESRLNLVQRNVNIFKFI
IPNVVKYSPNCKLLIVSNPVDILTYVAWKISGFPKNRVIGSGCNLDSARFRYLMGERLGV
HPLSCHGWVLGEHGDSSVPVWSGMNVAGVSLKTLHPDLGTDKDKEQWKEVHKQVVESAYE
VIKLKGYTSWAIGLSVADLAESIMKNLRRVHPVSTMIKGLYGIKDDVFLSVPCILGQNGI
SDLVKVTLTSEEEARLKKSADTLWGIQKELQF
|
|
|
|---|
| BDBM50066975 |
|---|
| n/a |
|---|
| Name | BDBM50066975 |
|---|
| Synonyms: | 7-Benzyl-2,3-dihydroxy-4-isopropyl-6-methyl-naphthalene-1-carboxylic acid | CHEMBL341463 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C22H22O4 |
|---|
| Mol. Mass. | 350.4077 |
|---|
| SMILES | CC(C)c1c(O)c(O)c(C(O)=O)c2cc(Cc3ccccc3)c(C)cc12 |
|---|
| Structure | 
|
|---|
Search and Browse
