| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A1 |
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| Ligand | BDBM50067096 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_29466 (CHEMBL642195) |
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| Ki | 3200000±n/a nM |
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| Citation |  van Muijlwijk-Koezen, JE; Timmerman, H; Link, R; van der Goot, H; Ijzerman, AP A novel class of adenosine A3 receptor ligands. 2. Structure affinity profile of a series of isoquinoline and quinazoline compounds. J Med Chem41:3994-4000 (1998) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A1 |
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| Name: | Adenosine receptor A1 |
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| Synonyms: | AA1R_RAT | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | Adenosine A1 receptor (A1) | Adenosine receptor | Adenosine receptors A1 | Adora1 |
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| Type: | Protein |
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| Mol. Mass.: | 36704.13 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | n/a |
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| Residue: | 326 |
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| Sequence: | MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA
LVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVT
QRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYM
VYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALIL
FLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFL
KIWNDHFRCQPKPPIDEDLPEEKAED
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| BDBM50067096 |
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| n/a |
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| Name | BDBM50067096 |
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| Synonyms: | CHEMBL71053 | N-(3-(pyridin-2-yl)isoquinolin-1-yl)benzamide | N-(3-Pyridin-2-yl-isoquinolin-1-yl)-benzamide | N-(3-Pyridin-2-yl-isoquinolin-1-yl)-benzamide(VUF8507) | VUF-8507 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H15N3O |
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| Mol. Mass. | 325.3633 |
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| SMILES | O=C(Nc1nc(cc2ccccc12)-c1ccccn1)c1ccccc1 |
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| Structure | 
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