| Reaction Details |
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 | Report a problem with these data |
| Target | Histamine H3 receptor |
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| Ligand | BDBM50067472 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_86901 (CHEMBL698411) |
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| Ki | 2.3±n/a nM |
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| Citation |  Krause, M; Ligneau, X; Stark, H; Garbarg, M; Schwartz, JC; Schunack, W 4-Alkynylphenyl imidazolylpropyl ethers as selective histamine H3-receptor antagonists with high oral central nervous system activity. J Med Chem41:4171-6 (1998) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Histamine H3 receptor |
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| Name: | Histamine H3 receptor |
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| Synonyms: | HH3R | HRH3_RAT | Hrh3 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 48607.98 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | n/a |
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| Residue: | 445 |
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| Sequence: | MERAPPDGLMNASGTLAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFV
ADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCAS
SVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGG
SSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAG
PEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVEAGEAALGGGSGGGAA
ASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSL
AIIVSIFGLCWAPYTLLMIIRAACHGRCIPDYWYETSFWLLWANSAVNPVLYPLCHYSFR
RAFTKLLCPQKLKVQPHGSLEQCWK
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| BDBM50067472 |
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| n/a |
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| Name | BDBM50067472 |
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| Synonyms: | 4-[3-(4-Ethynyl-phenoxy)-propyl]-1H-imidazole | 4-[3-(4-Ethynyl-phenoxy)-propyl]-1H-imidazole (FUB 470) | CHEMBL309600 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H14N2O |
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| Mol. Mass. | 226.2738 |
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| SMILES | C#Cc1ccc(OCCCc2cnc[nH]2)cc1 |
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| Structure | 
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