| Reaction Details |
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 | Report a problem with these data |
| Target | Coagulation factor X |
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| Ligand | BDBM50067530 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_48482 (CHEMBL662060) |
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| Ki | 4800±n/a nM |
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| Citation |  Gabriel, B; Stubbs, MT; Bergner, A; Hauptmann, J; Bode, W; Stürzebecher, J; Moroder, L Design of benzamidine-type inhibitors of factor Xa. J Med Chem41:4240-50 (1998) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Coagulation factor X |
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| Name: | Coagulation factor X |
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| Synonyms: | Coagulation factor X | F10 | FA10_BOVIN | Factor Xa (fXa) |
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| Type: | PROTEIN |
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| Mol. Mass.: | 54498.45 |
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| Organism: | Bos taurus |
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| Description: | ChEMBL_1364435 |
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| Residue: | 492 |
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| Sequence: | MAGLLHLVLLSTALGGLLRPAGSVFLPRDQAHRVLQRARRANSFLEEVKQGNLERECLEE
ACSLEEAREVFEDAEQTDEFWSKYKDGDQCEGHPCLNQGHCKDGIGDYTCTCAEGFEGKN
CEFSTREICSLDNGGCDQFCREERSEVRCSCAHGYVLGDDSKSCVSTERFPCGKFTQGRS
RRWAIHTSEDALDASELEHYDPADLSPTESSLDLLGLNRTEPSAGEDGSQVVRIVGGRDC
AEGECPWQALLVNEENEGFCGGTILNEFYVLTAAHCLHQAKRFTVRVGDRNTEQEEGNEM
AHEVEMTVKHSRFVKETYDFDIAVLRLKTPIRFRRNVAPACLPEKDWAEATLMTQKTGIV
SGFGRTHEKGRLSSTLKMLEVPYVDRSTCKLSSSFTITPNMFCAGYDTQPEDACQGDSGG
PHVTRFKDTYFVTGIVSWGEGCARKGKFGVYTKVSNFLKWIDKIMKARAGAAGSRGHSEA
PATWTVPPPLPL
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| BDBM50067530 |
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| n/a |
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| Name | BDBM50067530 |
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| Synonyms: | 3-(4-Carbamimidoyl-phenyl)-2-[2-(4-cyano-benzenesulfonylamino)-acetylamino]-propionic acid ethyl ester | CHEMBL135198 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H23N5O5S |
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| Mol. Mass. | 457.503 |
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| SMILES | CCOC(=O)C(Cc1ccc(cc1)C(N)=N)NC(=O)CNS(=O)(=O)c1ccc(cc1)C#N |
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| Structure | 
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