| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Sterol O-acyltransferase 2 |
|---|
| Ligand | BDBM50196069 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1849336 (CHEMBL4349877) |
|---|
| IC50 | 19100±n/a nM |
|---|
| Citation |  Ohshiro, T; Kobayashi, K; Suzuki, A; Yamazaki, H; Uchida, R; Namikoshi, M; Tomoda, H Inhibition of neutral lipid synthesis by avarols from a marine sponge. Bioorg Med Chem Lett29:2283-2285 (2019) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Sterol O-acyltransferase 2 |
|---|
| Name: | Sterol O-acyltransferase 2 |
|---|
| Synonyms: | ACAT-2 | ACAT2 | Acyl-coenzyme A:cholesterol acyltransferase 2 | Cholesterol acyltransferase 2 | SOAT2 | SOAT2_CHLAE | Sterol O-acyltransferase 2 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 60426.29 |
|---|
| Organism: | Chlorocebus aethiops |
|---|
| Description: | ChEMBL_116979 |
|---|
| Residue: | 526 |
|---|
| Sequence: | MEPGGARLRLQRTEGPGGEREHQPCRDGNTETHRAPDLVKWTRHMEAVKAQLLEQAQGQL
RELLDRAMWEAIQSYPSQDKPPPLPPPDSLSRTQEPSLGKQKVFIIRKSLLDELMEVQHF
RTIYHMFIAGLCVFIISTLAIDFIDEGRLLLEFDLLIFSFGQLPLALVTWVPMFLSTLLA
PYQALRLWARPGARGTWTLGAGLGCALLAAHALVLCALPVHVAVEHQLPPASRCVLVFEQ
VRFLMKSYSFLREAVPGTLRARRGEGIQAPSFSSYLYFLFCPTLIYRETYPRTPYIRWNY
VAKNFAQALGCVLYACFILGRLCVPVFANMSREPFSTRALVLSILHATLPGIFMLLLIFF
AFLHCWLNAFAEMLRFGDRMFYRDWWNSTSFSNYYRTWNVVVHDWLYSYVYQDGLWLLGA
QARGVAMLGVFLVSAVAHEYIFCFVLGFFYPVMLILFLVIGGMLNFMMHDQHTGPAWNVL
MWTMLFLGQGIQVSLYCQEWYARRHCPLPQTTFWGLVTPRSWSCHT
|
|
|
|---|
| BDBM50196069 |
|---|
| n/a |
|---|
| Name | BDBM50196069 |
|---|
| Synonyms: | CHEMBL3965313 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C21H30O2 |
|---|
| Mol. Mass. | 314.4617 |
|---|
| SMILES | [H][C@@]12CCCC(=C)[C@@]1(C)CC[C@H](C)[C@@]2(C)Cc1cc(O)ccc1O |r| |
|---|
| Structure | 
|
|---|
Search and Browse
