| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-lactamase |
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| Ligand | BDBM26140 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_35528 (CHEMBL649554) |
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| Ki | 220±n/a nM |
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| Citation |  Weston, GS; Blázquez, J; Baquero, F; Shoichet, BK Structure-based enhancement of boronic acid-based inhibitors of AmpC beta-lactamase. J Med Chem41:4577-86 (1998) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Beta-lactamase |
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| Name: | Beta-lactamase |
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| Synonyms: | AMPC_ECOLI | Beta-lactamase | Beta-lactamase (AmpC) | Beta-lactamase AmpC | Cephalosporinase | Escherichia coli K-12 | ampA | ampC |
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| Type: | Protien |
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| Mol. Mass.: | 41561.62 |
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| Organism: | Escherichia coli |
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| Description: | P00811 |
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| Residue: | 377 |
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| Sequence: | MFKTTLCALLITASCSTFAAPQQINDIVHRTITPLIEQQKIPGMAVAVIYQGKPYYFTWG
YADIAKKQPVTQQTLFELGSVSKTFTGVLGGDAIARGEIKLSDPTTKYWPELTAKQWNGI
TLLHLATYTAGGLPLQVPDEVKSSSDLLRFYQNWQPAWAPGTQRLYANSSIGLFGALAVK
PSGLSFEQAMQTRVFQPLKLNHTWINVPPAEEKNYAWGYREGKAVHVSPGALDAEAYGVK
STIEDMARWVQSNLKPLDINEKTLQQGIQLAQSRYWQTGDMYQGLGWEMLDWPVNPDSII
NGSDNKIALAARPVKAITPPTPAVRASWVHKTGATGGFGSYVAFIPEKELGIVMLANKNY
PNPARVDAAWQILNALQ
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| BDBM26140 |
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| n/a |
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| Name | BDBM26140 |
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| Synonyms: | 1-benzofuran-2-ylboranediol | 1-benzofuran-2-ylboronic acid, 19 | CHEMBL143399 | Phenylboronic acid, 21 |
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| Type | Small organic molecule |
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| Emp. Form. | C8H7BO3 |
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| Mol. Mass. | 161.95 |
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| SMILES | OB(O)c1cc2ccccc2o1 |
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| Structure | 
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