| Reaction Details |
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 | Report a problem with these data |
| Target | Glucagon receptor |
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| Ligand | BDBM50068640 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_72990 (CHEMBL680803) |
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| Ki | >500000±n/a nM |
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| Citation |  Madsen, P; Knudsen, LB; Wiberg, FC; Carr, RD Discovery and structure-activity relationship of the first non-peptide competitive human glucagon receptor antagonists. J Med Chem41:5150-7 (1999) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Glucagon receptor |
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| Name: | Glucagon receptor |
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| Synonyms: | GCGR | GL-R | GLR_HUMAN | Glucagon Receptor (GCGR) | Glucagon receptor (GlucR) |
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| Type: | Enzyme |
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| Mol. Mass.: | 54026.92 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P47871 |
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| Residue: | 477 |
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| Sequence: | MPPCQPQRPLLLLLLLLACQPQVPSAQVMDFLFEKWKLYGDQCHHNLSLLPPPTELVCNR
TFDKYSCWPDTPANTTANISCPWYLPWHHKVQHRFVFKRCGPDGQWVRGPRGQPWRDASQ
CQMDGEEIEVQKEVAKMYSSFQVMYTVGYSLSLGALLLALAILGGLSKLHCTRNAIHANL
FASFVLKASSVLVIDGLLRTRYSQKIGDDLSVSTWLSDGAVAGCRVAAVFMQYGIVANYC
WLLVEGLYLHNLLGLATLPERSFFSLYLGIGWGAPMLFVVPWAVVKCLFENVQCWTSNDN
MGFWWILRFPVFLAILINFFIFVRIVQLLVAKLRARQMHHTDYKFRLAKSTLTLIPLLGV
HEVVFAFVTDEHAQGTLRSAKLFFDLFLSSFQGLLVAVLYCFLNKEVQSELRRRWHRWRL
GKVLWEERNTSNHRASSSPGHGPPSKELQFGRGGGSQDSSAETPLAGGLPRLAESPF
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| BDBM50068640 |
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| n/a |
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| Name | BDBM50068640 |
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| Synonyms: | 1-(3,4-Dihydroxy-phenyl)-2-(1-methyl-1H-benzoimidazol-2-ylsulfanyl)-ethanone | CHEMBL147679 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H14N2O3S |
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| Mol. Mass. | 314.359 |
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| SMILES | Cn1c(SCC(=O)c2ccc(O)c(O)c2)nc2ccccc12 |
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| Structure | 
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