| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Transitional endoplasmic reticulum ATPase |
|---|
| Ligand | BDBM50514015 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1855348 (CHEMBL4356077) |
|---|
| Kd | 7000±n/a nM |
|---|
| Citation |  Huryn, DM; Kornfilt, DJP; Wipf, P p97: An Emerging Target for Cancer, Neurodegenerative Diseases, and Viral Infections. J Med Chem63:1892-1907 (2020) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Transitional endoplasmic reticulum ATPase |
|---|
| Name: | Transitional endoplasmic reticulum ATPase |
|---|
| Synonyms: | TERA_HUMAN | Transitional endoplasmic reticulum ATPase | VCP | Valosin containing protein, p97 subunit | Valosin-containing protein |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 89300.63 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P55072 |
|---|
| Residue: | 806 |
|---|
| Sequence: | MASGADSKGDDLSTAILKQKNRPNRLIVDEAINEDNSVVSLSQPKMDELQLFRGDTVLLK
GKKRREAVCIVLSDDTCSDEKIRMNRVVRNNLRVRLGDVISIQPCPDVKYGKRIHVLPID
DTVEGITGNLFEVYLKPYFLEAYRPIRKGDIFLVRGGMRAVEFKVVETDPSPYCIVAPDT
VIHCEGEPIKREDEEESLNEVGYDDIGGCRKQLAQIKEMVELPLRHPALFKAIGVKPPRG
ILLYGPPGTGKTLIARAVANETGAFFFLINGPEIMSKLAGESESNLRKAFEEAEKNAPAI
IFIDELDAIAPKREKTHGEVERRIVSQLLTLMDGLKQRAHVIVMAATNRPNSIDPALRRF
GRFDREVDIGIPDATGRLEILQIHTKNMKLADDVDLEQVANETHGHVGADLAALCSEAAL
QAIRKKMDLIDLEDETIDAEVMNSLAVTMDDFRWALSQSNPSALRETVVEVPQVTWEDIG
GLEDVKRELQELVQYPVEHPDKFLKFGMTPSKGVLFYGPPGCGKTLLAKAIANECQANFI
SIKGPELLTMWFGESEANVREIFDKARQAAPCVLFFDELDSIAKARGGNIGDGGGAADRV
INQILTEMDGMSTKKNVFIIGATNRPDIIDPAILRPGRLDQLIYIPLPDEKSRVAILKAN
LRKSPVAKDVDLEFLAKMTNGFSGADLTEICQRACKLAIRESIESEIRRERERQTNPSAM
EVEEDDPVPEIRRDHFEEAMRFARRSVSDNDIRKYEMFAQTLQQSRGFGSFRFPSGNQGG
AGPSQGSGGGTGGSVYTEDNDDDLYG
|
|
|
|---|
| BDBM50514015 |
|---|
| n/a |
|---|
| Name | BDBM50514015 |
|---|
| Synonyms: | CHEMBL4514514 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C24H20IN3O2 |
|---|
| Mol. Mass. | 509.339 |
|---|
| SMILES | [H][C@@]12CCCN1C(=O)c1ccccc1N\C2=C/C(=O)/C=C/c1c[nH]c2ccc(I)cc12 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
