| Reaction Details |
|---|
 | Report a problem with these data |
| Target | D(1A) dopamine receptor |
|---|
| Ligand | BDBM50070191 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_58297 |
|---|
| IC50 | 3540±n/a nM |
|---|
| Citation |  Mantegani, S; Brambilla, E; Caccia, C; Damiani, G; Fornaretto, MG; McArthur, RA; Varasi, M Serotonergic ergoline derivatives. Bioorg Med Chem Lett8:1117-22 (1999) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| D(1A) dopamine receptor |
|---|
| Name: | D(1A) dopamine receptor |
|---|
| Synonyms: | DOPAMINE D1 | DRD1_RAT | Dopamine D1 high | Dopamine D1 low | Dopamine receptor | Dopamine receptor D1 | Dopamine1-like | Drd1 | Drd1a |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 49429.75 |
|---|
| Organism: | RAT |
|---|
| Description: | P18901 |
|---|
| Residue: | 446 |
|---|
| Sequence: | MAPNTSTMDEAGLPAERDFSFRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNF
FVISLAVSDLLVAVLVMPWKAVAEIAGFWPLGPFCNIWVAFDIMCSTASILNLCVISVDR
YWAISSPFQYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTWPLDGNFTSLED
TEDDNCDTRLSRTYAISSSLISFYIPVAIMIVTYTSIYRIAQKQIRRISALERAAVHAKN
CQTTAGNGNPVECAQSESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFISNCMVPFCGS
EETQPFCIDSITFDVFVWFGWANSSLNPIIYAFNADFQKAFSTLLGCYRLCPTTNNAIET
VSINNNGAVVFSSHHEPRGSISKDCNLVYLIPHAVGSSEDLKKEEAGGIAKPLEKLSPAL
SVILDYDTDVSLEKIQPVTHSGQHST
|
|
|
|---|
| BDBM50070191 |
|---|
| n/a |
|---|
| Name | BDBM50070191 |
|---|
| Synonyms: | 1-((6aR,9R,10aR)-3-tert-Butyl-7-methyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinolin-9-ylmethyl)-imidazolidine-2,4-dione | CHEMBL13464 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C23H30N4O2 |
|---|
| Mol. Mass. | 394.5099 |
|---|
| SMILES | CN1C[C@H](Cn2cc(O)[nH]c2=O)C[C@H]2[C@H]1Cc1c[nH]c3c(ccc2c13)C(C)(C)C |
|---|
| Structure | 
|
|---|
Search and Browse
