Compile Data Set for Download or QSAR

Found 210 hits with Last Name = 'brambilla' and Initial = 'e'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Pteridine reductase 1 (Leishmania major)	BDBM50551183 (CHEMBL4747846) Show SMILES Oc1ccc(cc1)-c1ccc(-c2cc(O)cc(O)c2)c(c1)-c1ccccc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	5.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Leishmania major PTR1 using H2B as substrate preincubated for 10 mins followed by NADPH addition and measured up to 50 mins relative to...				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112047 BindingDB Entry DOI: 10.7270/Q2F47SSH
					More data for this Ligand-Target Pair
Pteridine reductase 1 (Leishmania major)	BDBM50551184 (CHEMBL4797185) Show SMILES Cn1cnc2c(N)nc(CCc3ccccc3)nc12 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Leishmania major PTR1 using H2B as substrate preincubated for 10 mins followed by NADPH addition and measured up to 50 mins relative to...				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112047 BindingDB Entry DOI: 10.7270/Q2F47SSH
					More data for this Ligand-Target Pair
Pteridine reductase 1 (Leishmania major)	BDBM50551180 (CHEMBL4760251) Show SMILES O=C1CCCCCNCc2ccc(Cc3ccc(CNCCCCCC(=O)N(Cc4ccccc4)CCCCCCCCN1Cc1ccccc1)cc3)cc2 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.48E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Leishmania major PTR1 using H2B as substrate preincubated for 10 mins followed by NADPH addition and measured up to 50 mins relative to...				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112047 BindingDB Entry DOI: 10.7270/Q2F47SSH
					More data for this Ligand-Target Pair
Pteridine reductase 1 (Leishmania major)	BDBM50551177 (CHEMBL4762279) Show SMILES Nc1cc(NCc2ccc(cc2)-c2ccccc2)nc(N)n1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.53E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Leishmania major PTR1 using H2B as substrate preincubated for 10 mins followed by NADPH addition and measured up to 50 mins relative to...				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112047 BindingDB Entry DOI: 10.7270/Q2F47SSH
					More data for this Ligand-Target Pair
Pteridine reductase 1 (Leishmania major)	BDBM50551178 (CHEMBL4785591) Show SMILES O=C1CCCCCNCc2ccc(cc2)-c2ccc(CNCCCCCC(=O)N(Cc3ccccc3)CCCCCCCCN1Cc1ccccc1)cc2 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.92E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Leishmania major PTR1 using H2B as substrate preincubated for 10 mins followed by NADPH addition and measured up to 50 mins relative to...				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112047 BindingDB Entry DOI: 10.7270/Q2F47SSH
					More data for this Ligand-Target Pair
Pteridine reductase 1 (Leishmania major)	BDBM50551181 (CHEMBL54725) Show SMILES COc1ccccc1CNCc1ccc(CNCCCCCCCCCCCCNCc2ccc(CNCc3ccccc3OC)cc2)cc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.72E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Leishmania major PTR1 using H2B as substrate preincubated for 10 mins followed by NADPH addition and measured up to 50 mins relative to...				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112047 BindingDB Entry DOI: 10.7270/Q2F47SSH
					More data for this Ligand-Target Pair
Pteridine reductase 1 (Leishmania major)	BDBM50551174 (CHEMBL158919) Show SMILES Nc1cc(NCc2ccccc2)nc(N)n1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Leishmania major PTR1 using H2B as substrate preincubated for 10 mins followed by NADPH addition and measured up to 50 mins relative to...				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112047 BindingDB Entry DOI: 10.7270/Q2F47SSH
					More data for this Ligand-Target Pair
Pteridine reductase 1 (Leishmania major)	BDBM50551179 (CHEMBL4778279) Show SMILES O=C1CCCCCNCc2ccc(CNCCCCCC(=O)N(Cc3ccccc3)CCCCCCCCN1Cc1ccccc1)cc2 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Leishmania major PTR1 using H2B as substrate preincubated for 10 mins followed by NADPH addition and measured up to 50 mins relative to...				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112047 BindingDB Entry DOI: 10.7270/Q2F47SSH
					More data for this Ligand-Target Pair
Pteridine reductase 1 (Leishmania major)	BDBM50551173 (CHEMBL4753331) Show SMILES COc1ccc(COc2cc(N)nc(N)n2)cc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Leishmania major PTR1 using H2B as substrate preincubated for 10 mins followed by NADPH addition and measured up to 50 mins relative to...				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112047 BindingDB Entry DOI: 10.7270/Q2F47SSH
					More data for this Ligand-Target Pair
Pteridine reductase 1 (Leishmania major)	BDBM50551176 (CHEMBL4748094) Show SMILES Nc1cc(NCc2ccc(F)cc2)nc(N)n1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Leishmania major PTR1 using H2B as substrate preincubated for 10 mins followed by NADPH addition and measured up to 50 mins relative to...				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112047 BindingDB Entry DOI: 10.7270/Q2F47SSH
					More data for this Ligand-Target Pair
Pteridine reductase 1 (Leishmania major)	BDBM50551182 (CHEMBL4754292) Show SMILES [H][C@@]12CCN(CCCCCCN)[C@]1([H])c1ccccc1OC2 |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Leishmania major PTR1 using H2B as substrate preincubated for 10 mins followed by NADPH addition and measured up to 50 mins relative to...				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112047 BindingDB Entry DOI: 10.7270/Q2F47SSH
					More data for this Ligand-Target Pair
Pteridine reductase 1 (Leishmania major)	BDBM50062821 (6-Benzyloxy-pyrimidine-2,4-diamine | CHEMBL121445) Show SMILES Nc1cc(OCc2ccccc2)nc(N)n1 Show InChI InChI=1S/C11H12N4O/c12-9-6-10(15-11(13)14-9)16-7-8-4-2-1-3-5-8/h1-6H,7H2,(H4,12,13,14,15)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Leishmania major PTR1 using H2B as substrate preincubated for 10 mins followed by NADPH addition and measured up to 50 mins relative to...				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112047 BindingDB Entry DOI: 10.7270/Q2F47SSH
					More data for this Ligand-Target Pair
Pteridine reductase 1 (Leishmania major)	BDBM50386758 (CHEMBL2046893) Show SMILES Fc1ccc(cc1)N(CCNCCCc1ccccc1)c1ccc(F)cc1 Show InChI InChI=1S/C23H24F2N2/c24-20-8-12-22(13-9-20)27(23-14-10-21(25)11-15-23)18-17-26-16-4-7-19-5-2-1-3-6-19/h1-3,5-6,8-15,26H,4,7,16-18H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Leishmania major PTR1 using H2B as substrate preincubated for 10 mins followed by NADPH addition and measured up to 50 mins relative to...				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112047 BindingDB Entry DOI: 10.7270/Q2F47SSH
					More data for this Ligand-Target Pair
Pteridine reductase 1 (Leishmania major)	BDBM50551175 (CHEMBL1993081) Show SMILES Nc1nc(NCc2ccccc2)cc(NCc2ccccc2)n1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Leishmania major PTR1 using H2B as substrate preincubated for 10 mins followed by NADPH addition and measured up to 50 mins relative to...				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112047 BindingDB Entry DOI: 10.7270/Q2F47SSH
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50289537 (1-(3-Phenyl-propyl)-3-((Z)-styryl)-piperidine | CH...) Show SMILES C(CN1CCCC(C1)\C=C/c1ccccc1)Cc1ccccc1 Show InChI InChI=1S/C22H27N/c1-3-9-20(10-4-1)13-7-17-23-18-8-14-22(19-23)16-15-21-11-5-2-6-12-21/h1-6,9-12,15-16,22H,7-8,13-14,17-19H2/b16-15-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity at sigma receptor by [3H]-(+)-SKF-10,047 displacement.				Bioorg Med Chem Lett 7: 1525-1530 (1997) Article DOI: 10.1016/S0960-894X(97)00253-9 BindingDB Entry DOI: 10.7270/Q2N58MCN
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50289553 (1-Phenethyl-3-((Z)-styryl)-piperidine | CHEMBL3697...) Show SMILES C(Cc1ccccc1)N1CCCC(C1)\C=C/c1ccccc1 Show InChI InChI=1S/C21H25N/c1-3-8-19(9-4-1)13-14-21-12-7-16-22(18-21)17-15-20-10-5-2-6-11-20/h1-6,8-11,13-14,21H,7,12,15-18H2/b14-13-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity at sigma receptor by [3H]-(+)-SKF-10,047 displacement.				Bioorg Med Chem Lett 7: 1525-1530 (1997) Article DOI: 10.1016/S0960-894X(97)00253-9 BindingDB Entry DOI: 10.7270/Q2N58MCN
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50289552 (1-(3-Methyl-but-2-enyl)-3-((Z)-styryl)-piperidine ...) Show SMILES [#6]\[#6](-[#6])=[#6]/[#6]-[#7]-1-[#6]-[#6]-[#6]-[#6](-[#6]-1)\[#6]=[#6]/c1ccccc1 Show InChI InChI=1S/C18H25N/c1-16(2)12-14-19-13-6-9-18(15-19)11-10-17-7-4-3-5-8-17/h3-5,7-8,10-12,18H,6,9,13-15H2,1-2H3/b11-10-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity at sigma receptor by [3H]-(+)-SKF-10,047 displacement.				Bioorg Med Chem Lett 7: 1525-1530 (1997) Article DOI: 10.1016/S0960-894X(97)00253-9 BindingDB Entry DOI: 10.7270/Q2N58MCN
					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)	BDBM50070198 ((6aR,9R,10aR)-3-tert-Butyl-7-methyl-4,6,6a,7,8,9,1...) Show SMILES CN1C[C@@H](C[C@H]2[C@H]1Cc1c[nH]c3c(ccc2c13)C(C)(C)C)C(=O)Nc1nccs1 Show InChI InChI=1S/C23H28N4OS/c1-23(2,3)17-6-5-15-16-9-14(21(28)26-22-24-7-8-29-22)12-27(4)18(16)10-13-11-25-20(17)19(13)15/h5-8,11,14,16,18,25H,9-10,12H2,1-4H3,(H,24,26,28)/t14-,16-,18-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia & Upjohn S.p.A.-CNS Research Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from 5-hydroxytryptamine 2 receptor in rat pre frontal cortex				Bioorg Med Chem Lett 8: 1117-22 (1999) BindingDB Entry DOI: 10.7270/Q2M61JF3
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50289539 (1-Cyclohexyl-3-((Z)-styryl)-piperidine | CHEMBL398...) Show SMILES C1CCC(CC1)N1CCCC(C1)\C=C/c1ccccc1 Show InChI InChI=1S/C19H27N/c1-3-8-17(9-4-1)13-14-18-10-7-15-20(16-18)19-11-5-2-6-12-19/h1,3-4,8-9,13-14,18-19H,2,5-7,10-12,15-16H2/b14-13-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity at sigma receptor by [3H]-(+)-SKF-10,047 displacement.				Bioorg Med Chem Lett 7: 1525-1530 (1997) Article DOI: 10.1016/S0960-894X(97)00253-9 BindingDB Entry DOI: 10.7270/Q2N58MCN
					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)	BDBM50070192 ((6aR,9R,10aR)-3-tert-Butyl-7-methyl-4,6,6a,7,8,9,1...) Show SMILES CN1C[C@@H](C[C@H]2[C@H]1Cc1c[nH]c3c(ccc2c13)C(C)(C)C)C(=O)Nc1ccc(Cl)nn1 Show InChI InChI=1S/C24H28ClN5O/c1-24(2,3)17-6-5-15-16-9-14(23(31)27-20-8-7-19(25)28-29-20)12-30(4)18(16)10-13-11-26-22(17)21(13)15/h5-8,11,14,16,18,26H,9-10,12H2,1-4H3,(H,27,29,31)/t14-,16-,18-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia & Upjohn S.p.A.-CNS Research Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from 5-hydroxytryptamine 2 receptor in rat pre frontal cortex				Bioorg Med Chem Lett 8: 1117-22 (1999) BindingDB Entry DOI: 10.7270/Q2M61JF3
					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)	BDBM50070187 (1-Acetyl-3-((6aR,9S,10aR)-3-tert-butyl-7-methyl-4,...) Show SMILES CN1C[C@H](CNC(=S)NC(C)=O)C[C@H]2[C@H]1Cc1c[nH]c3c(ccc2c13)C(C)(C)C Show InChI InChI=1S/C23H32N4OS/c1-13(28)26-22(29)25-10-14-8-17-16-6-7-18(23(2,3)4)21-20(16)15(11-24-21)9-19(17)27(5)12-14/h6-7,11,14,17,19,24H,8-10,12H2,1-5H3,(H2,25,26,28,29)/t14-,17+,19+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia & Upjohn S.p.A.-CNS Research Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from 5-hydroxytryptamine 2 receptor in rat pre frontal cortex				Bioorg Med Chem Lett 8: 1117-22 (1999) BindingDB Entry DOI: 10.7270/Q2M61JF3
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50289541 (1-(3-Phenyl-propyl)-3-((E)-styryl)-piperidine | CH...) Show SMILES C(CN1CCCC(C1)\C=C\c1ccccc1)Cc1ccccc1 Show InChI InChI=1S/C22H27N/c1-3-9-20(10-4-1)13-7-17-23-18-8-14-22(19-23)16-15-21-11-5-2-6-12-21/h1-6,9-12,15-16,22H,7-8,13-14,17-19H2/b16-15+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity at sigma receptor by [3H]-(+)-SKF-10,047 displacement.				Bioorg Med Chem Lett 7: 1525-1530 (1997) Article DOI: 10.1016/S0960-894X(97)00253-9 BindingDB Entry DOI: 10.7270/Q2N58MCN
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50289538 (1-Allyl-3-((E)-styryl)-piperidine | CHEMBL39735) Show SMILES C=CCN1CCCC(C1)\C=C\c1ccccc1 Show InChI InChI=1S/C16H21N/c1-2-12-17-13-6-9-16(14-17)11-10-15-7-4-3-5-8-15/h2-5,7-8,10-11,16H,1,6,9,12-14H2/b11-10+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity at sigma receptor by [3H]-(+)-SKF-10,047 displacement.				Bioorg Med Chem Lett 7: 1525-1530 (1997) Article DOI: 10.1016/S0960-894X(97)00253-9 BindingDB Entry DOI: 10.7270/Q2N58MCN
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50289547 (1-Phenethyl-3-((E)-styryl)-piperidine | CHEMBL2879...) Show SMILES C(Cc1ccccc1)N1CCCC(C1)\C=C\c1ccccc1 Show InChI InChI=1S/C21H25N/c1-3-8-19(9-4-1)13-14-21-12-7-16-22(18-21)17-15-20-10-5-2-6-11-20/h1-6,8-11,13-14,21H,7,12,15-18H2/b14-13+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity at sigma receptor by [3H]-(+)-SKF-10,047 displacement.				Bioorg Med Chem Lett 7: 1525-1530 (1997) Article DOI: 10.1016/S0960-894X(97)00253-9 BindingDB Entry DOI: 10.7270/Q2N58MCN
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50289549 (1-Cyclohexyl-3-((E)-styryl)-piperidine | CHEMBL291...) Show SMILES C1CCC(CC1)N1CCCC(C1)\C=C\c1ccccc1 Show InChI InChI=1S/C19H27N/c1-3-8-17(9-4-1)13-14-18-10-7-15-20(16-18)19-11-5-2-6-12-19/h1,3-4,8-9,13-14,18-19H,2,5-7,10-12,15-16H2/b14-13+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity at sigma receptor by [3H]-(+)-SKF-10,047 displacement.				Bioorg Med Chem Lett 7: 1525-1530 (1997) Article DOI: 10.1016/S0960-894X(97)00253-9 BindingDB Entry DOI: 10.7270/Q2N58MCN
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (RAT-NEONATAL RAT-Rattus norvegicus (rat))	BDBM50070193 (1-((6aR,9R,10aR)-2-tert-Butyl-7-methyl-4,6,6a,7,8,...) Show SMILES CCNC(=O)N(CCCN(C)C)C(=O)[C@@H]1C[C@H]2[C@@H](Cc3c[nH]c4cc(cc2c34)C(C)(C)C)N(C)C1 Show InChI InChI=1S/C28H43N5O2/c1-8-29-27(35)33(11-9-10-31(5)6)26(34)19-12-21-22-14-20(28(2,3)4)15-23-25(22)18(16-30-23)13-24(21)32(7)17-19/h14-16,19,21,24,30H,8-13,17H2,1-7H3,(H,29,35)/t19-,21-,24-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia & Upjohn S.p.A.-CNS Research Curated by ChEMBL					Assay Description Displacement of [3H]yohimbine from Alpha-2 adrenergic receptor in rat frontal cortex				Bioorg Med Chem Lett 8: 1117-22 (1999) BindingDB Entry DOI: 10.7270/Q2M61JF3
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50289551 (1-(4-Phenyl-butyl)-3-((Z)-styryl)-piperidine | CHE...) Show SMILES C(CCc1ccccc1)CN1CCCC(C1)\C=C/c1ccccc1 Show InChI InChI=1S/C23H29N/c1-3-10-21(11-4-1)14-7-8-18-24-19-9-15-23(20-24)17-16-22-12-5-2-6-13-22/h1-6,10-13,16-17,23H,7-9,14-15,18-20H2/b17-16-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity at sigma receptor by [3H]-(+)-SKF-10,047 displacement.				Bioorg Med Chem Lett 7: 1525-1530 (1997) Article DOI: 10.1016/S0960-894X(97)00253-9 BindingDB Entry DOI: 10.7270/Q2N58MCN
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50289545 (1-(2-Cyclohexyl-ethyl)-3-((Z)-styryl)-piperidine |...) Show SMILES C(CN1CCCC(C1)\C=C/c1ccccc1)C1CCCCC1 Show InChI InChI=1S/C21H31N/c1-3-8-19(9-4-1)13-14-21-12-7-16-22(18-21)17-15-20-10-5-2-6-11-20/h1,3-4,8-9,13-14,20-21H,2,5-7,10-12,15-18H2/b14-13-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity at sigma receptor by [3H]-(+)-SKF-10,047 displacement.				Bioorg Med Chem Lett 7: 1525-1530 (1997) Article DOI: 10.1016/S0960-894X(97)00253-9 BindingDB Entry DOI: 10.7270/Q2N58MCN
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50289536 (1-Benzyl-3-((E)-styryl)-piperidine | CHEMBL39855) Show SMILES C(N1CCCC(C1)\C=C\c1ccccc1)c1ccccc1 Show InChI InChI=1S/C20H23N/c1-3-8-18(9-4-1)13-14-20-12-7-15-21(17-20)16-19-10-5-2-6-11-19/h1-6,8-11,13-14,20H,7,12,15-17H2/b14-13+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity at sigma receptor by [3H]-(+)-SKF-10,047 displacement.				Bioorg Med Chem Lett 7: 1525-1530 (1997) Article DOI: 10.1016/S0960-894X(97)00253-9 BindingDB Entry DOI: 10.7270/Q2N58MCN
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50289554 (1-Pent-4-enyl-3-((E)-styryl)-piperidine | CHEMBL38...) Show SMILES C=CCCCN1CCCC(C1)\C=C\c1ccccc1 Show InChI InChI=1S/C18H25N/c1-2-3-7-14-19-15-8-11-18(16-19)13-12-17-9-5-4-6-10-17/h2,4-6,9-10,12-13,18H,1,3,7-8,11,14-16H2/b13-12+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity at sigma receptor by [3H]-(+)-SKF-10,047 displacement.				Bioorg Med Chem Lett 7: 1525-1530 (1997) Article DOI: 10.1016/S0960-894X(97)00253-9 BindingDB Entry DOI: 10.7270/Q2N58MCN
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50070203 (CHEMBL14048 | N-((6aR,9S,10aR)-7-Methyl-4,6,6a,7,8...) Show SMILES CN1C[C@H](CNC(=O)c2ccccc2)C[C@H]2[C@H]1Cc1c[nH]c3cccc2c13 Show InChI InChI=1S/C23H25N3O/c1-26-14-15(12-25-23(27)16-6-3-2-4-7-16)10-19-18-8-5-9-20-22(18)17(13-24-20)11-21(19)26/h2-9,13,15,19,21,24H,10-12,14H2,1H3,(H,25,27)/t15-,19+,21+/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia & Upjohn S.p.A.-CNS Research Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor in rat hippocampus				Bioorg Med Chem Lett 8: 1117-22 (1999) BindingDB Entry DOI: 10.7270/Q2M61JF3
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50289544 (1-Phenyl-4-[3-((Z)-styryl)-piperidin-1-yl]-butan-1...) Show SMILES O=C(CCCN1CCCC(C1)\C=C/c1ccccc1)c1ccccc1 Show InChI InChI=1S/C23H27NO/c25-23(22-12-5-2-6-13-22)14-8-18-24-17-7-11-21(19-24)16-15-20-9-3-1-4-10-20/h1-6,9-10,12-13,15-16,21H,7-8,11,14,17-19H2/b16-15-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity at sigma receptor by [3H]-(+)-SKF-10,047 displacement.				Bioorg Med Chem Lett 7: 1525-1530 (1997) Article DOI: 10.1016/S0960-894X(97)00253-9 BindingDB Entry DOI: 10.7270/Q2N58MCN
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50070201 (((6aR,9S,10aR)-2-tert-Butyl-7-methyl-4,6,6a,7,8,9,...) Show SMILES CN1C[C@H](CNC(=O)OCc2ccccc2)C[C@H]2[C@H]1Cc1c[nH]c3cc(cc2c13)C(C)(C)C Show InChI InChI=1S/C28H35N3O2/c1-28(2,3)21-12-23-22-10-19(14-30-27(32)33-17-18-8-6-5-7-9-18)16-31(4)25(22)11-20-15-29-24(13-21)26(20)23/h5-9,12-13,15,19,22,25,29H,10-11,14,16-17H2,1-4H3,(H,30,32)/t19-,22+,25+/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia & Upjohn S.p.A.-CNS Research Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor in rat hippocampus				Bioorg Med Chem Lett 8: 1117-22 (1999) BindingDB Entry DOI: 10.7270/Q2M61JF3
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50289540 (1-(3-Phenoxy-propyl)-3-((Z)-styryl)-piperidine | C...) Show SMILES C(COc1ccccc1)CN1CCCC(C1)\C=C/c1ccccc1 Show InChI InChI=1S/C22H27NO/c1-3-9-20(10-4-1)14-15-21-11-7-16-23(19-21)17-8-18-24-22-12-5-2-6-13-22/h1-6,9-10,12-15,21H,7-8,11,16-19H2/b15-14-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity at sigma receptor by [3H]-(+)-SKF-10,047 displacement.				Bioorg Med Chem Lett 7: 1525-1530 (1997) Article DOI: 10.1016/S0960-894X(97)00253-9 BindingDB Entry DOI: 10.7270/Q2N58MCN
					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)	BDBM50070191 (1-((6aR,9R,10aR)-3-tert-Butyl-7-methyl-4,6,6a,7,8,...) Show SMILES CN1C[C@H](Cn2cc(O)[nH]c2=O)C[C@H]2[C@H]1Cc1c[nH]c3c(ccc2c13)C(C)(C)C Show InChI InChI=1S/C23H30N4O2/c1-23(2,3)17-6-5-15-16-7-13(11-27-12-19(28)25-22(27)29)10-26(4)18(16)8-14-9-24-21(17)20(14)15/h5-6,9,12-13,16,18,24,28H,7-8,10-11H2,1-4H3,(H,25,29)/t13-,16-,18-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia & Upjohn S.p.A.-CNS Research Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from 5-hydroxytryptamine 2 receptor in rat pre frontal cortex				Bioorg Med Chem Lett 8: 1117-22 (1999) BindingDB Entry DOI: 10.7270/Q2M61JF3
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50289556 (1,1-Dioxo-2-{4-[3-((E)-styryl)-piperidin-1-yl]-but...) Show SMILES O=C1N(CCCCN2CCCC(C2)\C=C\c2ccccc2)S(=O)(=O)c2ccccc12 Show InChI InChI=1S/C24H28N2O3S/c27-24-22-12-4-5-13-23(22)30(28,29)26(24)18-7-6-16-25-17-8-11-21(19-25)15-14-20-9-2-1-3-10-20/h1-5,9-10,12-15,21H,6-8,11,16-19H2/b15-14+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity at sigma receptor by [3H]-(+)-SKF-10,047 displacement.				Bioorg Med Chem Lett 7: 1525-1530 (1997) Article DOI: 10.1016/S0960-894X(97)00253-9 BindingDB Entry DOI: 10.7270/Q2N58MCN
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50289557 (Adamantane-1-carboxylic acid {4-[3-((Z)-styryl)-pi...) Show SMILES O=C(NCCCCN1CCCC(C1)\C=C/c1ccccc1)C12C[C@H]3C[C@H](C[C@H](C3)C1)C2 Show InChI InChI=1S/C28H40N2O/c31-27(28-18-24-15-25(19-28)17-26(16-24)20-28)29-12-4-5-13-30-14-6-9-23(21-30)11-10-22-7-2-1-3-8-22/h1-3,7-8,10-11,23-26H,4-6,9,12-21H2,(H,29,31)/b11-10-/t23?,24-,25+,26-,28?	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity at sigma receptor by [3H]-(+)-SKF-10,047 displacement.				Bioorg Med Chem Lett 7: 1525-1530 (1997) Article DOI: 10.1016/S0960-894X(97)00253-9 BindingDB Entry DOI: 10.7270/Q2N58MCN
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50070185 (CHEMBL273526 | N-((6aR,9S,10aR)-2-tert-Butyl-7-met...) Show SMILES CN1C[C@H](CNC(=O)c2ccccc2)C[C@H]2[C@H]1Cc1c[nH]c3cc(cc2c13)C(C)(C)C Show InChI InChI=1S/C27H33N3O/c1-27(2,3)20-12-22-21-10-17(14-29-26(31)18-8-6-5-7-9-18)16-30(4)24(21)11-19-15-28-23(13-20)25(19)22/h5-9,12-13,15,17,21,24,28H,10-11,14,16H2,1-4H3,(H,29,31)/t17-,21+,24+/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia & Upjohn S.p.A.-CNS Research Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor in rat hippocampus				Bioorg Med Chem Lett 8: 1117-22 (1999) BindingDB Entry DOI: 10.7270/Q2M61JF3
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50289543 (2-{3-[3-((Z)-Styryl)-piperidin-1-yl]-propylsulfany...) Show SMILES C(CSc1nc2ccccc2s1)CN1CCCC(C1)\C=C/c1ccccc1 Show InChI InChI=1S/C23H26N2S2/c1-2-8-19(9-3-1)13-14-20-10-6-15-25(18-20)16-7-17-26-23-24-21-11-4-5-12-22(21)27-23/h1-5,8-9,11-14,20H,6-7,10,15-18H2/b14-13-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity at sigma receptor by [3H]-(+)-SKF-10,047 displacement.				Bioorg Med Chem Lett 7: 1525-1530 (1997) Article DOI: 10.1016/S0960-894X(97)00253-9 BindingDB Entry DOI: 10.7270/Q2N58MCN
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50070190 (((6aR,9S,10aR)-3-tert-Butyl-7-methyl-4,6,6a,7,8,9,...) Show SMILES CN1C[C@H](CNC(=O)OCc2ccccc2)C[C@H]2[C@H]1Cc1c[nH]c3c(ccc2c13)C(C)(C)C Show InChI InChI=1S/C28H35N3O2/c1-28(2,3)23-11-10-21-22-12-19(14-30-27(32)33-17-18-8-6-5-7-9-18)16-31(4)24(22)13-20-15-29-26(23)25(20)21/h5-11,15,19,22,24,29H,12-14,16-17H2,1-4H3,(H,30,32)/t19-,22+,24+/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia & Upjohn S.p.A.-CNS Research Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor in rat hippocampus				Bioorg Med Chem Lett 8: 1117-22 (1999) BindingDB Entry DOI: 10.7270/Q2M61JF3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50070202 (CHEMBL267799 | N-((6aR,9S,10aR)-3-tert-Butyl-7-met...) Show SMILES CN1C[C@H](CNC(=O)c2ccccc2)C[C@H]2[C@H]1Cc1c[nH]c3c(ccc2c13)C(C)(C)C Show InChI InChI=1S/C27H33N3O/c1-27(2,3)22-11-10-20-21-12-17(14-29-26(31)18-8-6-5-7-9-18)16-30(4)23(21)13-19-15-28-25(22)24(19)20/h5-11,15,17,21,23,28H,12-14,16H2,1-4H3,(H,29,31)/t17-,21+,23+/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia & Upjohn S.p.A.-CNS Research Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor in rat hippocampus				Bioorg Med Chem Lett 8: 1117-22 (1999) BindingDB Entry DOI: 10.7270/Q2M61JF3
					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)	BDBM50070188 (1-((6aR,9R,10aR)-3-tert-Butyl-7-methyl-4,6,6a,7,8,...) Show SMILES CCNC(=O)N(CCCN(C)C)C(=O)[C@@H]1C[C@H]2[C@@H](Cc3c[nH]c4c(ccc2c34)C(C)(C)C)N(C)C1 Show InChI InChI=1S/C28H43N5O2/c1-8-29-27(35)33(13-9-12-31(5)6)26(34)19-14-21-20-10-11-22(28(2,3)4)25-24(20)18(16-30-25)15-23(21)32(7)17-19/h10-11,16,19,21,23,30H,8-9,12-15,17H2,1-7H3,(H,29,35)/t19-,21-,23-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia & Upjohn S.p.A.-CNS Research Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from 5-hydroxytryptamine 2 receptor in rat pre frontal cortex				Bioorg Med Chem Lett 8: 1117-22 (1999) BindingDB Entry DOI: 10.7270/Q2M61JF3
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50289550 (1-(3-Phenoxy-propyl)-3-((E)-styryl)-piperidine | C...) Show SMILES C(COc1ccccc1)CN1CCCC(C1)\C=C\c1ccccc1 Show InChI InChI=1S/C22H27NO/c1-3-9-20(10-4-1)14-15-21-11-7-16-23(19-21)17-8-18-24-22-12-5-2-6-13-22/h1-6,9-10,12-15,21H,7-8,11,16-19H2/b15-14+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity at sigma receptor by [3H]-(+)-SKF-10,047 displacement.				Bioorg Med Chem Lett 7: 1525-1530 (1997) Article DOI: 10.1016/S0960-894X(97)00253-9 BindingDB Entry DOI: 10.7270/Q2N58MCN
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50289546 (1-(3-Methyl-but-2-enyl)-3-((E)-styryl)-piperidine ...) Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-[#7]-1-[#6]-[#6]-[#6]-[#6](-[#6]-1)\[#6]=[#6]\c1ccccc1 Show InChI InChI=1S/C18H25N/c1-16(2)12-14-19-13-6-9-18(15-19)11-10-17-7-4-3-5-8-17/h3-5,7-8,10-12,18H,6,9,13-15H2,1-2H3/b11-10+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity at sigma receptor by [3H]-(+)-SKF-10,047 displacement.				Bioorg Med Chem Lett 7: 1525-1530 (1997) Article DOI: 10.1016/S0960-894X(97)00253-9 BindingDB Entry DOI: 10.7270/Q2N58MCN
					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)	BDBM50070202 (CHEMBL267799 | N-((6aR,9S,10aR)-3-tert-Butyl-7-met...) Show SMILES CN1C[C@H](CNC(=O)c2ccccc2)C[C@H]2[C@H]1Cc1c[nH]c3c(ccc2c13)C(C)(C)C Show InChI InChI=1S/C27H33N3O/c1-27(2,3)22-11-10-20-21-12-17(14-29-26(31)18-8-6-5-7-9-18)16-30(4)23(21)13-19-15-28-25(22)24(19)20/h5-11,15,17,21,23,28H,12-14,16H2,1-4H3,(H,29,31)/t17-,21+,23+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia & Upjohn S.p.A.-CNS Research Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from 5-hydroxytryptamine 2 receptor in rat pre frontal cortex				Bioorg Med Chem Lett 8: 1117-22 (1999) BindingDB Entry DOI: 10.7270/Q2M61JF3
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50070181 (1-(3-Dimethylamino-propyl)-3-ethyl-1-((6aR,9R,10aR...) Show SMILES CCNC(=O)N(CCCN(C)C)C(=O)[C@@H]1C[C@H]2[C@@H](Cc3c[nH]c4cccc2c34)N(C)C1 Show InChI InChI=1S/C24H35N5O2/c1-5-25-24(31)29(11-7-10-27(2)3)23(30)17-12-19-18-8-6-9-20-22(18)16(14-26-20)13-21(19)28(4)15-17/h6,8-9,14,17,19,21,26H,5,7,10-13,15H2,1-4H3,(H,25,31)/t17-,19-,21-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia & Upjohn S.p.A.-CNS Research Curated by ChEMBL					Assay Description Displacement of [3H]-spiroperidol from D2 receptor in rat striatum				Bioorg Med Chem Lett 8: 1117-22 (1999) BindingDB Entry DOI: 10.7270/Q2M61JF3
					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)	BDBM50070190 (((6aR,9S,10aR)-3-tert-Butyl-7-methyl-4,6,6a,7,8,9,...) Show SMILES CN1C[C@H](CNC(=O)OCc2ccccc2)C[C@H]2[C@H]1Cc1c[nH]c3c(ccc2c13)C(C)(C)C Show InChI InChI=1S/C28H35N3O2/c1-28(2,3)23-11-10-21-22-12-19(14-30-27(32)33-17-18-8-6-5-7-9-18)16-31(4)24(22)13-20-15-29-26(23)25(20)21/h5-11,15,19,22,24,29H,12-14,16-17H2,1-4H3,(H,30,32)/t19-,22+,24+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	54	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia & Upjohn S.p.A.-CNS Research Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from 5-hydroxytryptamine 2 receptor in rat pre frontal cortex				Bioorg Med Chem Lett 8: 1117-22 (1999) BindingDB Entry DOI: 10.7270/Q2M61JF3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50070184 (((6aR,9S,10aR)-7-Methyl-4,6,6a,7,8,9,10,10a-octahy...) Show SMILES CN1C[C@H](CNC(=O)OCc2ccccc2)C[C@H]2[C@H]1Cc1c[nH]c3cccc2c13 Show InChI InChI=1S/C24H27N3O2/c1-27-14-17(12-26-24(28)29-15-16-6-3-2-4-7-16)10-20-19-8-5-9-21-23(19)18(13-25-21)11-22(20)27/h2-9,13,17,20,22,25H,10-12,14-15H2,1H3,(H,26,28)/t17-,20+,22+/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia & Upjohn S.p.A.-CNS Research Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor in rat hippocampus				Bioorg Med Chem Lett 8: 1117-22 (1999) BindingDB Entry DOI: 10.7270/Q2M61JF3
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50289542 (3-((Z)-Styryl)-piperidine | CHEMBL38345) Show SMILES C1CNCC(C1)\C=C/c1ccccc1 Show InChI InChI=1S/C13H17N/c1-2-5-12(6-3-1)8-9-13-7-4-10-14-11-13/h1-3,5-6,8-9,13-14H,4,7,10-11H2/b9-8-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	64	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity at sigma receptor by [3H]-(+)-SKF-10,047 displacement.				Bioorg Med Chem Lett 7: 1525-1530 (1997) Article DOI: 10.1016/S0960-894X(97)00253-9 BindingDB Entry DOI: 10.7270/Q2N58MCN
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50070203 (CHEMBL14048 | N-((6aR,9S,10aR)-7-Methyl-4,6,6a,7,8...) Show SMILES CN1C[C@H](CNC(=O)c2ccccc2)C[C@H]2[C@H]1Cc1c[nH]c3cccc2c13 Show InChI InChI=1S/C23H25N3O/c1-26-14-15(12-25-23(27)16-6-3-2-4-7-16)10-19-18-8-5-9-20-22(18)17(13-24-20)11-21(19)26/h2-9,13,15,19,21,24H,10-12,14H2,1H3,(H,25,27)/t15-,19+,21+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	75	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia & Upjohn S.p.A.-CNS Research Curated by ChEMBL					Assay Description Displacement of [3H]-spiroperidol from D2 receptor in rat striatum				Bioorg Med Chem Lett 8: 1117-22 (1999) BindingDB Entry DOI: 10.7270/Q2M61JF3
					More data for this Ligand-Target Pair

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