| Reaction Details |
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 | Report a problem with these data |
| Target | Sigma non-opioid intracellular receptor 1 |
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| Ligand | BDBM50289557 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_201293 |
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| IC50 | 23±n/a nM |
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| Citation |  Mantegani, S; Brambilla, E; Cremonesi, P; Caccia, C; Fornaretto, MG; Carfagna, N; Colombo, M; McArthur, RA; Varasi, M (E) and (Z)-3-Styrylpiperidines as sigma ligands Bioorg Med Chem Lett7:1525-1530 (1997) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sigma non-opioid intracellular receptor 1 |
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| Name: | Sigma non-opioid intracellular receptor 1 |
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| Synonyms: | Opioid receptor | Oprs1 | SGMR1_RAT | Sigma | Sigma non-opioid intracellular receptor 1 | Sigma opioid receptor | Sigma-1 | Sigmar1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 25266.54 |
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| Organism: | RAT |
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| Description: | Q9R0C9 |
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| Residue: | 223 |
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| Sequence: | MPWAVGRRWAWITLFLTIVAVLIQAVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSR
LIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSHGHSGRY
WAEISDTIISGTFHQWREGTTKSEVYYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLAFALSDTIFSTQDFLTLFYTLRAYARGLRLELTTYLFGQDP
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| BDBM50289557 |
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| n/a |
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| Name | BDBM50289557 |
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| Synonyms: | Adamantane-1-carboxylic acid {4-[3-((Z)-styryl)-piperidin-1-yl]-butyl}-amide | CHEMBL39017 |
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| Type | Small organic molecule |
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| Emp. Form. | C28H40N2O |
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| Mol. Mass. | 420.63 |
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| SMILES | O=C(NCCCCN1CCCC(C1)\C=C/c1ccccc1)C12C[C@H]3C[C@H](C[C@H](C3)C1)C2 |
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| Structure | 
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